Publications by authors named "Rune Toftgard"

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Severe liver disease resembling PSC in mice with K5-Cre mediated deletion of Krüppel-like factor 5 (Klf5).
Åsa Bergström, Marco Gerling, Noémi Van Hul, Carlos Fernández Moro, Björn Rozell

Transgenic Res· October 2021

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GLI1-induced mammary gland tumours are transplantable and maintain major molecular features.
Jens Henrik Norum, Oliver Frings, Maria Kasper, Helga Bergholtz, Helene Zell Thime

Int J Cancer· February 2020

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Isolation and Fluorescence-Activated Cell Sorting of Mouse Keratinocytes Expressing β-Galactosidase.
Maria Kasper, Rune Toftgård, Viljar Jaks

Methods Mol Biol· January 2018

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Differential requirement of SUFU in tissue development discovered in a hypomorphic mouse model.
Maria A Hoelzl, Karin Heby-Henricson, Marco Gerling, José M Dias, Raoul V Kuiper

Dev Biol· September 2017

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Lgr6 labels a rare population of mammary gland progenitor cells that are able to originate luminal mammary tumours.
Leander Blaas, Fabio Pucci, Hendrik A Messal, Agneta B Andersson, E Josue Ruiz

Nat Cell Biol· December 2016

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Erratum: Stromal Hedgehog signalling is downregulated in colon cancer and its restoration restrains tumour growth.
Marco Gerling, Nikè V J A Büller, Leonard M Kirn, Simon Joost, Oliver Frings

Nat Commun· September 2016

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Stromal Hedgehog signalling is downregulated in colon cancer and its restoration restrains tumour growth.
Marco Gerling, Nikè V J A Büller, Leonard M Kirn, Simon Joost, Oliver Frings

Nat Commun· August 2016

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SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development.
Madalina Raducu, Ella Fung, Sébastien Serres, Paola Infante, Alessandro Barberis

EMBO J· July 2016

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FNDC4 acts as an anti-inflammatory factor on macrophages and improves colitis in mice.
Madeleen Bosma, Marco Gerling, Jenny Pasto, Anastasia Georgiadi, Evan Graham

Nat Commun· April 2016

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Suppressor of Fused Plays an Important Role in Regulating Mesodermal Differentiation of Murine Embryonic Stem Cells In Vivo.
Maria A Hoelzl, Karin Heby-Henricson, Ganna Bilousova, Björn Rozell, Raoul V Kuiper

Stem Cells Dev· November 2015

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Dynamics of Lgr6⁺ Progenitor Cells in the Hair Follicle, Sebaceous Gland, and Interfollicular Epidermis.
Anja Füllgrabe, Simon Joost, Alexandra Are, Tina Jacob, Unnikrishnan Sivan

Stem Cell Reports· November 2015

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A conditional transgenic mouse line for targeted expression of the stem cell marker LGR5.
Jens Henrik Norum, Åsa Bergström, Agneta Birgitta Andersson, Raoul V Kuiper, Maria A Hoelzl

Dev Biol· August 2015

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β-Catenin-Gli1 interaction regulates proliferation and tumor growth in medulloblastoma.
Jenny Zinke, Fabian T Schneider, Patrick N Harter, Sonja Thom, Nicole Ziegler

Mol Cancer· February 2015

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Think inside the BOCs: a mechanism underlying medulloblastoma progression.
Matthias Lauth, Rune Toftgard

Dev Cell· October 2014

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Regulated splicing of the α6 integrin cytoplasmic domain determines the fate of breast cancer stem cells.
Hira Lal Goel, Tatiana Gritsko, Bryan Pursell, Cheng Chang, Leonard D Shultz, Rune Toftgard

Cell Rep· May 2014

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Structural basis of SUFU-GLI interaction in human Hedgehog signalling regulation.
Amy L Cherry, Csaba Finta, Mikael Karlström, Qianren Jin, Thomas Schwend

Acta Crystallogr D Biol Crystallogr· December 2013

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Tumor necrosis factor receptor signaling in keratinocytes triggers interleukin-24-dependent psoriasis-like skin inflammation in mice.
Snehlata Kumari, Marion C Bonnet, Maria H Ulvmar, Kerstin Wolk, Niki Karagianni, Rune Toftgard

Immunity· November 2013

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Early and persisting response to vismodegib in a patient with bone metastasizing medulloblastoma.
Thomas Asklund, Roger Henriksson, Jan Axelsson, Åsa Bergström, Maria Kasper

Acta Oncol· May 2013

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GLI1 regulates a novel neuropilin-2/α6β1 integrin based autocrine pathway that contributes to breast cancer initiation.
Hira Lal Goel, Bryan Pursell, Cheng Chang, Leslie M Shaw, Junhao Mao, Rune Toftgard

EMBO Mol Med· April 2013

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Hedgehog signalling stimulates precursor cell accumulation and impairs epithelial maturation in the murine oesophagus.
Willemijn A van Dop, Sanne L Rosekrans, Anja Uhmann, Viljar Jaks, G Johan A Offerhaus

Gut· March 2013

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3D pancreatic carcinoma spheroids induce a matrix-rich, chemoresistant phenotype offering a better model for drug testing.
Paola Longati, Xiaohui Jia, Johannes Eimer, Annika Wagman, Michael-Robin Witt

BMC Cancer· February 2013

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Smoothing out drug resistance.
Maria Kasper, Rune Toftgård

Cancer Cell· January 2013

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Loss of Trp53 promotes medulloblastoma development but not skin tumorigenesis in Sufu heterozygous mutant mice.
Karin Heby-Henricson, Asa Bergström, Björn Rozell, Rune Toftgård, Stephan Teglund

Mol Carcinog· September 2012

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Basal cell carcinoma - molecular biology and potential new therapies.
Maria Kasper, Viljar Jaks, Daniel Hohl, Rune Toftgård

J Clin Invest· February 2012

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Targeted expression of GLI1 in the salivary glands results in an altered differentiation program and hyperplasia.
Marie Fiaschi, Asa Kolterud, Mats Nilsson, Rune Toftgård, Björn Rozell

Am J Pathol· November 2011

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