Publications by authors named "Ruth A Roberts"

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Use of new approach methodologies (NAMs) in epilepsy research and seizure risk assessment.
Ruth A Roberts, Mamta Behl, Helena T Hogberg, Eduardo Dunayevich, Michael Morton

Drug Discov Today· December 2025

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Is ChatGPT Ready for Public Use in Organ-Specific Drug Toxicity Research?
Skylar Connor, Leihong Wu, Ruth A Roberts, Weida Tong

Drug Discov Today· February 2025

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Drug-induced kidney injury: challenges and opportunities.
Skylar Connor, Ruth A Roberts, Weida Tong

Toxicol Res (Camb)· August 2024

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Academic drug discovery: Challenges and opportunities.
Angela J Murray, Liam R Cox, Holly V Adcock, Ruth A Roberts

Drug Discov Today· April 2024

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Generation of a drug-induced renal injury list to facilitate the development of new approach methodologies for nephrotoxicity.
Skylar Connor, Ting Li, Yanyan Qu, Ruth A Roberts, Weida Tong

Drug Discov Today· April 2024

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Data science in drug discovery safety: Challenges and opportunities.
Nicholas J Coltman, Ruth A Roberts, James E Sidaway

Exp Biol Med (Maywood)· November 2023

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Key Characteristics of Human Hepatotoxicants as a Basis for Identification and Characterization of the Causes of Liver Toxicity.
Ivan Rusyn, Xabier Arzuaga, Russell C Cattley, J Christopher Corton, Stephen S Ferguson, Ruth A Roberts

Hepatology· December 2021

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AI-based language models powering drug discovery and development.
Zhichao Liu, Ruth A Roberts, Madhu Lal-Nag, Xi Chen, Ruili Huang

Drug Discov Today· November 2021

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Species-Specific Urothelial Toxicity With an Anti-HIV Noncatalytic Site Integrase Inhibitor (NCINI) Is Related to Unusual pH-Dependent Physicochemical Changes.
Ruth A Roberts, Richard A Campbell, Phumzile Sikakana, Claire Sadler, Mark Osier

Toxicol Sci· August 2021

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A decade of toxicological trends: what the papers say.
Phumzile Sikakana, Ruth A Roberts

Toxicol Res (Camb)· September 2020

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New ideas for non-animal approaches to predict repeated-dose systemic toxicity: Report from an EPAA Blue Sky Workshop.
Catherine Mahony, Randolph S Ashton, Barbara Birk, Alan R Boobis, Tom Cull, Ruth A Roberts

Regul Toxicol Pharmacol· July 2020

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Innovative models for detection of seizure.
Kimberly L Rockley, Ruth A Roberts, Michael J Morton

Toxicol Res (Camb)· November 2019

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Collaboration, competition and publication in toxicology: views of British Toxicology Society members.
Emma S Walker, Ruth A Roberts, Jason H Gill

Toxicol Res (Camb)· July 2019

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Understanding drug targets: no such thing as bad news.
Ruth A Roberts

Drug Discov Today· December 2018

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Drug discovery and development: Biomarkers of neurotoxicity and neurodegeneration.
Abigail L Walker, Syed Z Imam, Ruth A Roberts

Exp Biol Med (Maywood)· September 2018

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Collaboration and competition: ethics in toxicology.
Emma S Walker, Ruth A Roberts

Toxicol Res (Camb)· July 2018

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Translational Biomarkers of Neurotoxicity: A Health and Environmental Sciences Institute Perspective on the Way Forward.
Ruth A Roberts, Michael Aschner, David Calligaro, Tomas R Guilarte, Joseph P Hanig

Toxicol Sci· December 2015

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Skin sensitization induced Langerhans' cell mobilization: variable requirements for tumour necrosis factor-α.
Laura H Eaton, Ruth A Roberts, Ian Kimber, Rebecca J Dearman, Aleksandra Metryka

Immunology· January 2015

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De novo LINE-1 retrotransposition in HepG2 cells preferentially targets gene poor regions of chromosome 13.
Pasano Bojang, Mark J Anderton, Ruth A Roberts, Kenneth S Ramos

Genomics· August 2014

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An integrated characterization of serological, pathological, and functional events in doxorubicin-induced cardiotoxicity.
Laura Cove-Smith, Neil Woodhouse, Adam Hargreaves, Jason Kirk, Susan Smith, Ruth A Roberts

Toxicol Sci· July 2014

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Reducing attrition in drug development: smart loading preclinical safety assessment.
Ruth A Roberts, Stefan L Kavanagh, Howard R Mellor, Christopher E Pollard, Sally Robinson

Drug Discov Today· March 2014

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Reprogramming of the HepG2 genome by long interspersed nuclear element-1.
Pasano Bojang, Ruth A Roberts, Mark J Anderton, Kenneth S Ramos

Mol Oncol· August 2013

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Target organ toxicities in studies conducted to support first time in man dosing: an analysis across species and therapy areas.
Steve Horner, David Ryan, Sally Robinson, Richard Callander, Katie Stamp, Ruth A Roberts

Regul Toxicol Pharmacol· April 2013

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What it means to be global.
Ruth A Roberts, Robert Wallis, Jin Ren, Jan Willem van der Laan, Peter J Sausen

Toxicol Sci· May 2012

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Low-dose 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine causes inflammatory activation of astrocytes in nuclear factor-κB reporter mice prior to loss of dopaminergic neurons.
James A Miller, Briana R Trout, Kelly A Sullivan, Russell A Bialecki, Ruth A Roberts

J Neurosci Res· March 2011

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