Publications by authors named "Ruth Chu"

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Potency-optimized CD28-activating bispecific antibody for the targeted treatment of Nectin-4 positive cancers.
Manpreet Kaur, Katja Rüger, Elaine C Chen, Udaya S Rangaswamy, Laura M Davison, Ruth Chu

J Immunother Cancer· April 2025

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Alternating Arenavirus Vector Immunization Generates Robust Polyfunctional Genotype Cross-Reactive Hepatitis B Virus-Specific CD8 T-Cell Responses and High Anti-Hepatitis B Surface Antigen Titers.
Sarah Schmidt, Meron Mengistu, Stephane Daffis, Sarah Ahmadi-Erber, Daniela Deutschmann, Ruth Chu

J Infect Dis· April 2024

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Therapeutic Potential of TLR8 Agonist GS-9688 (Selgantolimod) in Chronic Hepatitis B: Remodeling of Antiviral and Regulatory Mediators.
Oliver E Amin, Emily J Colbeck, Stephane Daffis, Shahzada Khan, Dhivya Ramakrishnan, Ruth Chu

Hepatology· July 2021

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Toll-Like Receptor 8 Agonist GS-9688 Induces Sustained Efficacy in the Woodchuck Model of Chronic Hepatitis B.
Stephane Daffis, Scott Balsitis, Jason Chamberlain, Jim Zheng, Rex Santos, Ruth Chu

Hepatology· January 2021

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Toll-like receptor 7 agonist GS-9620 induces prolonged inhibition of HBV via a type I interferon-dependent mechanism.
Congrong Niu, Li Li, Stephane Daffis, Julie Lucifora, Marc Bonnin, Ruth Chu

J Hepatol· May 2018

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Adenosine A₁ receptors do not play a major role in the regulation of lipogenic gene expression in hepatocytes.
Ming Yang, Ruth Chu, Jeffrey W Chisholm, Holger Doege, Luiz Belardinelli

Eur J Pharmacol· May 2012

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Selective concomitant inhibition of mTORC1 and mTORC2 activity in estrogen receptor negative breast cancer cells by BN107 and oleanolic acid.
Ruth Chu, Xiaoyue Zhao, Chandi Griffin, Richard E Staub, Mark Shoemaker

Int J Cancer· September 2010

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Uncoupling of ATP-mediated calcium signaling and dysregulated interleukin-6 secretion in dendritic cells by nanomolar thimerosal.
Samuel R Goth, Ruth A Chu, Jeffrey P Gregg, Gennady Cherednichenko, Isaac N Pessah

Environ Health Perspect· July 2006

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Oxygen tension regulates the in vitro maturation of GM-CSF expanded murine bone marrow dendritic cells by modulating class II MHC expression.
Samuel R Goth, Ruth A Chu, Isaac N Pessah

J Immunol Methods· January 2006

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