Publications by authors named "Ruth Lyons"

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Mapping the Proteomic Landscape of Pancreatic Cancer: Prognostic Insights and Subtype Stratification.
Adel T Aref, Jason Grealey, Mohashin Pathan, Zainab Noor, Asim Anees, Ruth J Lyons

Cancer Res Commun· October 2025

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Targeting the NPY/NPY1R signaling axis in mutant p53-dependent pancreatic cancer impairs metastasis.
Cecilia R Chambers, Supitchaya Watakul, Peter Schofield, Anna E Howell, Jessie Zhu, Ruth J Lyons

Sci Adv· March 2025

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Spatial Transcriptomics Reveals Novel Mechanisms Involved in Perineural Invasion in Pancreatic Ductal Adenocarcinomas.
Vanessa Lakis, Noni L Chan, Ruth Lyons, Nicola Blackburn, Tam Hong Nguyen

Cancers (Basel)· March 2025

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Multiomic Insights into Human Health: Gut Microbiomes of Hunter-Gatherer, Agropastoral, and Western Urban Populations.
Harinder Singh, Rosana Wiscovitch-Russo, Claire Kuelbs, Josh Espinoza, Amanda E Appel, Ruth J Lyons

bioRxiv· September 2024

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Temporally resolved proteomics identifies nidogen-2 as a cotarget in pancreatic cancer that modulates fibrosis and therapy response.
Brooke A Pereira, Shona Ritchie, Cecilia R Chambers, Katie A Gordon, Astrid Magenau, Ruth J Lyons

Sci Adv· July 2024

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African-specific molecular taxonomy of prostate cancer.
Weerachai Jaratlerdsiri, Jue Jiang, Tingting Gong, Sean M Patrick, Cali Willet, Ruth J Lyons

Nature· September 2022

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Genome-wide interrogation of structural variation reveals novel African-specific prostate cancer oncogenic drivers.
Tingting Gong, Weerachai Jaratlerdsiri, Jue Jiang, Cali Willet, Tracy Chew, Ruth J Lyons

Genome Med· August 2022

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Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status.
Kendelle J Murphy, Daniel A Reed, Claire Vennin, James R W Conway, Max Nobis, Ruth J Lyons, J Guy Lyons

Sci Adv· October 2021

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Author Correction: Human origins in a southern African palaeo-wetland and first migrations.
Eva K F Chan, Axel Timmermann, Benedetta F Baldi, Andy E Moore, Ruth J Lyons

Nature· April 2021

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Prostate cancer cell-intrinsic interferon signaling regulates dormancy and metastatic outgrowth in bone.
Katie L Owen, Linden J Gearing, Damien J Zanker, Natasha K Brockwell, Weng Hua Khoo, Ruth J Lyons

EMBO Rep· June 2020

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The Impact of Whole Genome Data on Therapeutic Decision-Making in Metastatic Prostate Cancer: A Retrospective Analysis.
Megan Crumbaker, Eva K F Chan, Tingting Gong, Niall Corcoran, Weerachai Jaratlerdsiri, Ruth J Lyons

Cancers (Basel)· May 2020

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Canfam_GSD: De novo chromosome-length genome assembly of the German Shepherd Dog (Canis lupus familiaris) using a combination of long reads, optical mapping, and Hi-C.
Matt A Field, Benjamin D Rosen, Olga Dudchenko, Eva K F Chan, Andre E Minoche, Ruth J Lyons

Gigascience· April 2020

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Author Correction: Diagnosis of fusion genes using targeted RNA sequencing.
Erin E Heyer, Ira W Deveson, Danson Wooi, Christina I Selinger, Ruth J Lyons

Nat Commun· April 2020

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Metagenomic analysis reveals a rich bacterial content in high-risk prostate tumors from African men.
Ye Feng, Weerachai Jaratlerdsiri, Sean M Patrick, Ruth J Lyons, Anne-Maree Haynes

Prostate· November 2019

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TMPRSS2-ERG fusions linked to prostate cancer racial health disparities: A focus on Africa.
James Blackburn, Stefano Vecchiarelli, Erin E Heyer, Sean M Patrick, Ruth J Lyons

Prostate· July 2019

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African KhoeSan ancestry linked to high-risk prostate cancer.
Desiree C Petersen, Weerachai Jaratlerdsiri, Abraham van Wyk, Eva K F Chan, Pedro Fernandez, Ruth J Lyons

BMC Med Genomics· June 2019

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Diagnosis of fusion genes using targeted RNA sequencing.
Erin E Heyer, Ira W Deveson, Danson Wooi, Christina I Selinger, Ruth J Lyons

Nat Commun· March 2019

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Optical mapping reveals a higher level of genomic architecture of chained fusions in cancer.
Eva K F Chan, Daniel L Cameron, Desiree C Petersen, Ruth J Lyons, Benedetta F Baldi

Genome Res· May 2018

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Altered mitochondrial genome content signals worse pathology and prognosis in prostate cancer.
Anton M F Kalsbeek, Eva K F Chan, Judith Grogan, Desiree C Petersen, Weerachai Jaratlerdsiri, Ruth J Lyons

Prostate· January 2018

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Mutational load of the mitochondrial genome predicts pathological features and biochemical recurrence in prostate cancer.
Anton M F Kalsbeek, Eva F K Chan, Judith Grogan, Desiree C Petersen, Weerachai Jaratlerdsiri, Ruth J Lyons

Aging (Albany NY)· October 2016

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Spectrum of mitochondrial genomic variation and associated clinical presentation of prostate cancer in South African men.
John P McCrow, Desiree C Petersen, Melanie Louw, Eva K F Chan, Katherine Harmeyer, Ruth J Lyons

Prostate· March 2016

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Profiling the tyrosine phosphoproteome of different mouse mammary tumour models reveals distinct, model-specific signalling networks and conserved oncogenic pathways.
Naveid A Ali, Jianmin Wu, Falko Hochgräfe, Howard Chan, Radhika Nair, Ruth J Lyons

Breast Cancer Res· September 2014

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Retinal characteristics of the congenital disorder of glycosylation PMM2-CDG.
Dorothy A Thompson, Ruth J Lyons, Isabelle Russell-Eggitt, Alki Liasis, Herbert Jägle

J Inherit Metab Dis· November 2013

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PDZ-RhoGEF and LARG are essential for embryonic development and provide a link between thrombin and LPA receptors and Rho activation.
Constantinos M Mikelis, Todd R Palmby, May Simaan, Wenling Li, Roman Szabo, Ruth Lyons

J Biol Chem· April 2013

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