Publications by authors named "Ruth March"

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Divergent trajectories to structural diversity impact patient survival in high grade serous ovarian cancer.
Ailith Ewing, Alison Meynert, Ryan Silk, Stuart Aitken, Devin P Bendixsen, Ruth March

Nat Commun· July 2025

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Somatic BRCA1/2 mutations are associated with a similar survival advantage to their germline counterparts in tubo-ovarian high grade serous carcinoma.
Robert L Hollis, Michael Churchman, Graeme R Grimes, Alison M Meynert, Philippe Gautier, Ruth March

Eur J Cancer· March 2025

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Assessing the contribution of rare protein-coding germline variants to prostate cancer risk and severity in 37,184 cases.
Jonathan Mitchell, Niedzica Camacho, Patrick Shea, Konrad H Stopsack, Vijai Joseph, Ruth March

Nat Commun· February 2025

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Genetic architecture of telomere length in 462,666 UK Biobank whole-genome sequences.
Oliver S Burren, Ryan S Dhindsa, Sri V V Deevi, Sean Wen, Abhishek Nag, Ruth E March

Nat Genet· September 2024

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Characterising the contribution of rare protein-coding germline variants to prostate cancer risk and severity in 37,184 cases.
Jonathan Mitchell, Niedzica Camacho, Patrick Shea, Konrad H Stopsack, Vijai Joseph, Ruth March

medRxiv· May 2024

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Multiomic Characterization of High-Grade Serous Ovarian Carcinoma Enables High-Resolution Patient Stratification.
Robert L Hollis, Alison M Meynert, Caroline O Michie, Tzyvia Rye, Michael Churchman, Ruth March

Clin Cancer Res· August 2022

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Integrated analyses of growth differentiation factor-15 concentration and cardiometabolic diseases in humans.
Susanna Lemmelä, Eleanor M Wigmore, Christian Benner, Aki S Havulinna, Rachel M Y Ong, Ruth March

Elife· August 2022

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Rare variant contribution to human disease in 281,104 UK Biobank exomes.
Quanli Wang, Ryan S Dhindsa, Keren Carss, Andrew R Harper, Abhishek Nag, Ruth March

Nature· September 2021

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Structural Variants at the Loci are a Common Source of Homologous Repair Deficiency in High-grade Serous Ovarian Carcinoma.
Ailith Ewing, Alison Meynert, Michael Churchman, Graeme R Grimes, Robert L Hollis, Ruth March

Clin Cancer Res· June 2021

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A novel automated SARS-CoV-2 saliva PCR test protects a global asymptomatic workforce.
Nikki Carter, Maryam Clausen, Rebecca A Halpin, Colin Blackmore, Kang Cai, Ruth March

Sci Rep· June 2021

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Exome-Based Rare-Variant Analyses in CKD.
Sophia Cameron-Christie, Charles J Wolock, Emily Groopman, Slavé Petrovski, Sitharthan Kamalakaran, Ruth E March

J Am Soc Nephrol· June 2019

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Diagnostic Utility of Exome Sequencing for Kidney Disease.
Emily E Groopman, Maddalena Marasa, Sophia Cameron-Christie, Slavé Petrovski, Vimla S Aggarwal, Ruth March

N Engl J Med· January 2019

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Impact of a five-dimensional framework on R&D productivity at AstraZeneca.
Paul Morgan, Dean G Brown, Simon Lennard, Mark J Anderton, J Carl Barrett, Ruth E March

Nat Rev Drug Discov· March 2018

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Personalized/Precision Medicine/Personalised Healthcare: the art of giving different names to the same thing?
Ruth March, Cecilia Schott

Per Med· November 2017

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Gene mapping strategies for complex disease and drug response.
Ansar Jawaid, Rachael Moore, Ruth March, Bryan J Barratt

Drug Discov Today Technol· July 2014

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Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework.
David Cook, Dearg Brown, Robert Alexander, Ruth March, Paul Morgan

Nat Rev Drug Discov· June 2014

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Interstitial lung disease in gefitinib-treated Japanese patients with non-small-cell lung cancer: genome-wide analysis of genetic data.
Fredrik Nyberg, Bryan J Barratt, Taisei Mushiroda, Atsushi Takahashi, Ansar Jawaid, Ruth March

Pharmacogenomics· July 2011

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Delivering on the promise of personalized healthcare.
Ruth March

Per Med· May 2010

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Challenges and opportunities of pharmacogenetics in drug development.
Ruth March

Per Med· May 2006

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Serious carbamazepine-induced hypersensitivity reactions associated with the HSP70 gene cluster.
Ana Alfirevic, Tracy Mills, Pauline Harrington, Tracy Pinel, James Sherwood, Ruth E March

Pharmacogenet Genomics· April 2006

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Selecting cases from nuclear families for case-control association analysis.
Rachael M Moore, Tracy Pinel, Jing Hua Zhao, Ruth March, Ansar Jawaid

BMC Genet· December 2005

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Rosuvastatin pharmacokinetics and pharmacogenetics in white and Asian subjects residing in the same environment.
Edmund Lee, Stephen Ryan, Bruce Birmingham, Julie Zalikowski, Ruth March

Clin Pharmacol Ther· October 2005

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Automation and validation of DNA-banking systems.
Melissa Thornton, Amanda Gladwin, Robin Payne, Rachael Moore, Carl Cresswell, Ruth March

Drug Discov Today· October 2005

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Novel technology and the development of pharmacogenetics within the pharmaceutical industry.
Neil Gibson, Ansar Jawaid, Ruth March

Pharmacogenomics· June 2005

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