Publications by authors named "Dearg Brown"

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Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework.
David Cook, Dearg Brown, Robert Alexander, Ruth March, Paul Morgan

Nat Rev Drug Discov· June 2014

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The discovery of N-cyclopropyl-4-methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxoquinazolin-3(4H)-yl]benzamide (AZD6703), a clinical p38α MAP kinase inhibitor for the treatment of inflammatory diseases.
Dearg S Brown, John G Cumming, Paul Bethel, Jonathan Finlayson, Stefan Gerhardt

Bioorg Med Chem Lett· June 2012

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Balancing hERG affinity and absorption in the discovery of AZD5672, an orally active CCR5 antagonist for the treatment of rheumatoid arthritis.
John G Cumming, Howard Tucker, John Oldfield, Colin Fielding, Adrian Highton, Dearg Brown

Bioorg Med Chem Lett· February 2012

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Strategies to improve in vivo toxicology outcomes for basic candidate drug molecules.
Tim Luker, Lilian Alcaraz, Kamaldeep K Chohan, Niklas Blomberg, Dearg S Brown

Bioorg Med Chem Lett· October 2011

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A novel series of p38 MAP kinase inhibitors for the potential treatment of rheumatoid arthritis.
Dearg S Brown, Andrew J Belfield, George R Brown, Douglas Campbell, Alan Foubister

Bioorg Med Chem Lett· November 2004

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Multi-step application of immobilized reagents and scavengers: a total synthesis of epothilone C.
R Ian Storer, Toshiyasu Takemoto, Philip S Jackson, Dearg S Brown, Ian R Baxendale

Chemistry· May 2004

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