Publications by authors named "Ruud Out"

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Bone Marrow Farnesoid X Receptor Deficiency Does Not Impact Atherosclerosis Susceptibility in Male Low-Density Lipoprotein Receptor Knockout Mice.
Menno Hoekstra, Ruud Out, Zhaosha Li, Reeni B Hildebrand, Theo J C Van Berkel

Arterioscler Thromb Vasc Biol· September 2025

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Searching for avidity by chemical ligation of combinatorially self-assembled DNA-encoded ligand libraries.
Stefan Matysiak, Klaus Hellmuth, Afaf H El-Sagheer, Arun Shivalingam, Yavuz Ariyurek, Ruud Out

Org Biomol Chem· December 2017

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New technologies for DNA analysis--a review of the READNA Project.
Steven McGinn, David Bauer, Thomas Brefort, Liqin Dong, Afaf El-Sagheer, Ruud Out

N Biotechnol· May 2016

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Znf202 affects high density lipoprotein cholesterol levels and promotes hepatosteatosis in hyperlipidemic mice.
Carlos L J Vrins, Ruud Out, Peter van Santbrink, André van der Zee, Tokameh Mahmoudi

PLoS One· September 2013

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Human ATP-binding cassette G1 controls macrophage lipoprotein lipase bioavailability and promotes foam cell formation.
Maryline Olivier, Michael W Tanck, Ruud Out, Elise F Villard, Bart Lammers, J Wouter Jukema

Arterioscler Thromb Vasc Biol· September 2012

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Effects of deletion of macrophage ABCA7 on lipid metabolism and the development of atherosclerosis in the presence and absence of ABCA1.
Illiana Meurs, Laura Calpe-Berdiel, Kim L L Habets, Ying Zhao, Suzanne J A Korporaal, Ruud Out

PLoS One· July 2012

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The effect of ABCG1 deficiency on atherosclerotic lesion development in LDL receptor knockout mice depends on the stage of atherogenesis.
Illiana Meurs, Bart Lammers, Ying Zhao, Ruud Out, Reeni B Hildebrand

Atherosclerosis· March 2012

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Apolipoprotein isoform E4 does not increase coronary heart disease risk in carriers of low-density lipoprotein receptor mutations.
Jorie Versmissen, Daniëlla M Oosterveer, Menno Hoekstra, Ruud Out, Jimmy F P Berbée

Circ Cardiovasc Genet· December 2011

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Liver X receptors inhibit macrophage proliferation through downregulation of cyclins D1 and B1 and cyclin-dependent kinases 2 and 4.
Mónica Pascual-García, José M Carbó, Theresa León, Jonathan Matalonga, Ruud Out

J Immunol· April 2011

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Macrophage adipose triglyceride lipase deficiency attenuates atherosclerotic lesion development in low-density lipoprotein receptor knockout mice.
Bart Lammers, Prakash G Chandak, Elma Aflaki, Gijs H M Van Puijvelde, Branislav Radovic, Ruud Out

Arterioscler Thromb Vasc Biol· January 2011

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Genetic variant of the scavenger receptor BI in humans.
Menno Vergeer, Suzanne J A Korporaal, Remco Franssen, Illiana Meurs, Ruud Out

N Engl J Med· January 2011

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Enhanced foam cell formation, atherosclerotic lesion development, and inflammation by combined deletion of ABCA1 and SR-BI in Bone marrow-derived cells in LDL receptor knockout mice on western-type diet.
Ying Zhao, Marieke Pennings, Reeni B Hildebrand, Dan Ye, Laura Calpe-Berdiel, Ruud Out

Circ Res· December 2010

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The scavenger receptor class B, type I is a primary determinant of paraoxonase-1 association with high-density lipoproteins.
Richard W James, Marie-Claude Brulhart-Meynet, Anurag Kumar Singh, Brigitte Riederer, Ursula Seidler, Ruud Out

Arterioscler Thromb Vasc Biol· November 2010

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The E3 ubiquitin ligase IDOL induces the degradation of the low density lipoprotein receptor family members VLDLR and ApoER2.
Cynthia Hong, Sarah Duit, Pilvi Jalonen, Ruud Out, Lilith Scheer

J Biol Chem· June 2010

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Hepatic glycosphingolipid deficiency and liver function in mice.
Richard Jennemann, Ulrike Rothermel, Shijun Wang, Roger Sandhoff, Sylvia Kaden, Ruud Out

Hepatology· May 2010

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Lack of Abcg1 results in decreased plasma HDL cholesterol levels and increased biliary cholesterol secretion in mice fed a high cholesterol diet.
Harmen Wiersma, Niels Nijstad, Jan Freark de Boer, Ruud Out, Wytse Hogewerf

Atherosclerosis· September 2009

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Independent protective roles for macrophage Abcg1 and Apoe in the atherosclerotic lesion development.
Bart Lammers, Ruud Out, Reeni B Hildebrand, Carmel M Quinn, David Williamson

Atherosclerosis· August 2009

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Activation of the nuclear receptor PXR decreases plasma LDL-cholesterol levels and induces hepatic steatosis in LDL receptor knockout mice.
Menno Hoekstra, Bart Lammers, Ruud Out, Zhaosha Li, Miranda Van Eck

Mol Pharm· March 2009

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Apolipoprotein CI inhibits scavenger receptor BI and increases plasma HDL levels in vivo.
Willeke de Haan, Ruud Out, Jimmy F P Berbée, Caroline C van der Hoogt, Ko Willems van Dijk, J Wouter Jukema

Biochem Biophys Res Commun· December 2008

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The hepatic uptake of VLDL in lrp-ldlr-/-vldlr-/- mice is regulated by LPL activity and involves proteoglycans and SR-BI.
Lihui Hu, Caroline C van der Hoogt, Sonia M S Espirito Santo, Ruud Out, Kyriakos E Kypreos

J Lipid Res· July 2008

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Absence of HDL cholesteryl ester uptake in mice via SR-BI impairs an adequate adrenal glucocorticoid-mediated stress response to fasting.
Menno Hoekstra, Illiana Meurs, Mieke Koenders, Ruud Out, Reeni B Hildebrand

J Lipid Res· April 2008

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Combined deletion of macrophage ABCA1 and ABCG1 leads to massive lipid accumulation in tissue macrophages and distinct atherosclerosis at relatively low plasma cholesterol levels.
Ruud Out, Menno Hoekstra, Kim Habets, Illiana Meurs, Vivian de Waard

Arterioscler Thromb Vasc Biol· February 2008

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Scavenger receptor BI facilitates the metabolism of VLDL lipoproteins in vivo.
Miranda Van Eck, Menno Hoekstra, Ruud Out, I Sophie T Bos, J Kar Kruijt

J Lipid Res· January 2008

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Coexistence of foam cells and hypocholesterolemia in mice lacking the ABC transporters A1 and G1.
Ruud Out, Wendy Jessup, Wilfried Le Goff, Menno Hoekstra, Ingrid C Gelissen

Circ Res· January 2008

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Platelet activation by oxidized low density lipoprotein is mediated by CD36 and scavenger receptor-A.
Suzanne J A Korporaal, Miranda Van Eck, Jelle Adelmeijer, Martin Ijsseldijk, Ruud Out

Arterioscler Thromb Vasc Biol· November 2007

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