Publications by authors named "Ryan A Dick"

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Discovery of Edecesertib (GS-5718): A Potent, Selective Inhibitor of IRAK4.
Stephen E Ammann, Jeromy J Cottell, Nathan E Wright, Matthew R Warr, Chelsea A Snyder, Ryan A Dick

J Med Chem· June 2025

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First-in-Human Evaluation of Safety, Pharmacokinetics and Muscle Glycogen Lowering of a Novel Glycogen Synthase 1 Inhibitor for the Treatment of Pompe Disease.
Julie C Ullman, Ryan A Dick, Daniela Linzner, Todd Minga, Samnang Tep

Clin Pharmacol Ther· December 2024

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Discovery of Hepatitis B Virus Surface Antigen Suppressor GS-8873.
Darryl Kato, Regina Wai-Yan Choy, Eda Canales, Ryan A Dick, April D Lake

ACS Med Chem Lett· April 2024

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Small-molecule inhibition of glycogen synthase 1 for the treatment of Pompe disease and other glycogen storage disorders.
Julie C Ullman, Kevin T Mellem, Yannan Xi, Vyas Ramanan, Hanne Merritt, Ryan A Dick

Sci Transl Med· January 2024

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Refinement of In Vitro Methods for Identification of Aldehyde Oxidase Substrates Reveals Metabolites of Kinase Inhibitors.
Ryan A Dick

Drug Metab Dispos· June 2018

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Enzymes and inhibitors in neonicotinoid insecticide metabolism.
Xueyan Shi, Ryan A Dick, Kevin A Ford, John E Casida

J Agric Food Chem· June 2009

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Nitroso-imidacloprid irreversibly inhibits rabbit aldehyde oxidase.
Ryan A Dick, David B Kanne, John E Casida

Chem Res Toxicol· December 2007

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Substrate specificity of rabbit aldehyde oxidase for nitroguanidine and nitromethylene neonicotinoid insecticides.
Ryan A Dick, David B Kanne, John E Casida

Chem Res Toxicol· January 2006

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Neonicotinoid nitroguanidine insecticide metabolites: synthesis and nicotinic receptor potency of guanidines, aminoguanidines, and their derivatives.
David B Kanne, Ryan A Dick, Motohiro Tomizawa, John E Casida

Chem Res Toxicol· September 2005

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Identification of aldehyde oxidase as the neonicotinoid nitroreductase.
Ryan A Dick, David B Kanne, John E Casida

Chem Res Toxicol· February 2005

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The catalytic and kinetic mechanisms of NADPH-dependent alkenal/one oxidoreductase.
Ryan A Dick, Thomas W Kensler

J Biol Chem· April 2004

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NADPH alkenal/one oxidoreductase activity determines sensitivity of cancer cells to the chemotherapeutic alkylating agent irofulven.
Ryan A Dick, Xiang Yu, Thomas W Kensler

Clin Cancer Res· February 2004

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Chemoprotective potential of phase 2 enzyme inducers.
Ryan A Dick, Thomas W Kensler

Expert Rev Anticancer Ther· October 2002

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