Publications by authors named "Ryan Corcoran"

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Phase 1/2 trial of encorafenib, cetuximab, and nivolumab in microsatellite stable BRAF metastatic colorectal cancer.
Van K Morris, Christine M Parseghian, Vahid Bahrambeigi, Nourhan Abdelfattah, Lianchun Xiao, Ryan B Corcoran

Cancer Cell· November 2025

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TOP1 Mutations and Cross-Resistance to Antibody-Drug Conjugates in Patients with Metastatic Breast Cancer.
Rachel O Abelman, Bogang Wu, Haley Barnes, Arielle Medford, Bryanna Norden, Ryan B Corcoran

Clin Cancer Res· May 2025

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Adaptive Plasticity Tumor Cells Modulate MAPK-Targeting Therapy Response in Colorectal Cancer.
Oscar E Villarreal, Yixin Xu, Ha Tran, Annette Machado, Dionne Prescod, Ryan Corcoran

bioRxiv· January 2025

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The differential immunological impact of photon vs proton radiation therapy in high-grade lymphopenia in patients with gastrointestinal tumors.
James M Heather, Daniel W Kim, Sean M Sepulveda, Emily E van Seventer, Madeleine G Fish, Ryan Corcoran

Clin Exp Immunol· January 2025

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A unique interplay of access and selection shapes peritoneal metastasis evolution in colorectal cancer.
Emma Ce Wassenaar, Alexander N Gorelick, Wei-Ting Hung, David M Cheek, Emre Kucukkose, Ryan B Corcoran

bioRxiv· September 2024

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Minimal Residual Disease using a Plasma-Only Circulating Tumor DNA Assay to Predict Recurrence of Metastatic Colorectal Cancer Following Curative Intent Treatment.
Aparna R Parikh, Bryant H Chee, Jill Tsai, Thereasa A Rich, Kristin S Price, Ryan B Corcoran

Clin Cancer Res· July 2024

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Sotorasib Is a Pan-RASG12C Inhibitor Capable of Driving Clinical Response in NRASG12C Cancers.
Douglas A Rubinson, Noritaka Tanaka, Ferran Fece de la Cruz, Kevin S Kapner, Michael H Rosenthal, Ryan B Corcoran

Cancer Discov· May 2024

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The Irreversible FGFR Inhibitor KIN-3248 Overcomes FGFR2 Kinase Domain Mutations.
Eranga R Balasooriya, Qibiao Wu, Haley Ellis, Yuanli Zhen, Bryanna L Norden, Ryan B Corcoran

Clin Cancer Res· May 2024

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Phase I/II Study of Combined BCL-xL and MEK Inhibition with Navitoclax and Trametinib in KRAS or NRAS Mutant Advanced Solid Tumors.
Ryan B Corcoran, Khanh T Do, Jeong E Kim, James M Cleary, Aparna R Parikh

Clin Cancer Res· May 2024

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Allosteric PI3Kα Inhibition Overcomes On-target Resistance to Orthosteric Inhibitors Mediated by Secondary PIK3CA Mutations.
Andreas Varkaris, Ferran Fece de la Cruz, Elizabeth E Martin, Bryanna L Norden, Nicholas Chevalier, Ryan B Corcoran

Cancer Discov· February 2024

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Landscape of Clinical Resistance Mechanisms to FGFR Inhibitors in FGFR2-Altered Cholangiocarcinoma.
Qibiao Wu, Haley Ellis, Giulia Siravegna, Alexa G Michel, Bryanna L Norden, Ryan B Corcoran

Clin Cancer Res· January 2024

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Patient-Reported Outcomes, Tumor Markers, and Survival Outcomes in Advanced GI Cancer.
Joy X Jarnagin, Anurag Saraf, Islam Baiev, Gary Chi, Emily E van Seventer, Ryan B Corcoran

JAMA Netw Open· November 2023

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Novel Clinical Tool to Estimate Risk of False-Negative KRAS Mutations in Circulating Tumor DNA Testing.
Stefania Napolitano, Aparna R Parikh, Jason Henry, Christine M Parseghian, Jason Willis, Ryan B Corcoran

JCO Precis Oncol· September 2023

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A single inhibitor for all KRAS mutations.
Ryan B Corcoran

Nat Cancer· August 2023

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Targeting TBK1 to overcome resistance to cancer immunotherapy.
Yi Sun, Or-Yam Revach, Seth Anderson, Emily A Kessler, Clara H Wolfe, Ryan B Corcoran

Nature· March 2023

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Ultrasensitive detection of circulating LINE-1 ORF1p as a specific multi-cancer biomarker.
Martin S Taylor, Wu Connie, Peter C Fridy, Stephanie J Zhang, Yasmeen Senussi, Ryan B Corcoran

bioRxiv· March 2023

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Combined PD-1, BRAF and MEK inhibition in BRAF colorectal cancer: a phase 2 trial.
Jun Tian, Jonathan H Chen, Sherry X Chao, Karin Pelka, Marios Giannakis, Ryan B Corcoran

Nat Med· February 2023

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Line by Line: Distinct Patterns of Anti-EGFR Antibody Resistance by Line of Therapy.
Ryan B Corcoran

J Clin Oncol· January 2023

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Chromatin-bound RB targets promoters, enhancers, and CTCF-bound loci and is redistributed by cell-cycle progression.
Ioannis Sanidas, Hanjun Lee, Purva H Rumde, Gaylor Boulay, Robert Morris, Ryan B Corcoran

Mol Cell· September 2022

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Cell-free human papillomavirus DNA kinetics after surgery for human papillomavirus-associated oropharyngeal cancer.
Connor J O'Boyle, Giulia Siravegna, Shohreh Varmeh, Natalia Queenan, Alexa Michel, Ryan B Corcoran

Cancer· June 2022

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Reverse Transcriptase Inhibition Disrupts Repeat Element Life Cycle in Colorectal Cancer.
Mihir Rajurkar, Aparna R Parikh, Alexander Solovyov, Eunae You, Anupriya S Kulkarni, Ryan B Corcoran

Cancer Discov· June 2022

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KRAS-independent feedback activation of wild-type RAS constrains KRAS inhibitor efficacy.
Meagan B Ryan, Oluwadara Coker, Alexey Sorokin, Katerina Fella, Haley Barnes, Ryan B Corcoran

Cell Rep· June 2022

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Cell-Free HPV DNA Provides an Accurate and Rapid Diagnosis of HPV-Associated Head and Neck Cancer.
Giulia Siravegna, Connor J O'Boyle, Shohreh Varmeh, Natalia Queenan, Alexa Michel, Ryan B Corcoran

Clin Cancer Res· February 2022

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Radiation therapy enhances immunotherapy response in microsatellite stable colorectal and pancreatic adenocarcinoma in a phase II trial.
Aparna R Parikh, Annamaria Szabolcs, Jill N Allen, Jeffrey W Clark, Jennifer Y Wo, Ryan B Corcoran

Nat Cancer· November 2021

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