Publications by authors named "Ryan D Cohen"

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Characterization of the tautomeric equilibrium of molnupiravir, an antiviral for the treatment of COVID-19.
Samantha A Burgess, Xiao Wang, Dirk Stueber, Yunyi Wang, Ryan D Cohen

J Pharm Biomed Anal· November 2025

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Asymmetric Synthesis of MK-7845, an Investigational Treatment for COVID-19.
Reed T Larson, Ben W H Turnbull, Patrick J Moon, Dan Lehnherr, Jonathan M E Hughes, Ryan D Cohen

Org Lett· November 2025

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Insights into the Biosynthesis of Kibdelomycin and Amycolamicin from Comparative Biosynthetic Gene Cluster Analysis and Precursor Incorporation Studies.
Marina Sánchez-Hidalgo, José Miguel Quesada, Daniel Oves-Costales, Jonah Fine, Jesús Martín, Ryan D Cohen

J Nat Prod· August 2025

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Ultra-clean pure shift NMR with optimal water suppression for analysis of aqueous pharmaceutical samples.
Guilherme Dal Poggetto, Adam DiCaprio, Mikhail Reibarkh, Ryan D Cohen

Analyst· April 2024

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Unequivocal identification of two-bond heteronuclear correlations in natural products at nanomole scale by i-HMBC.
Yunyi Wang, Aili Fan, Ryan D Cohen, Guilherme Dal Poggetto, Zheng Huang

Nat Commun· April 2023

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DELTA50: A Highly Accurate Database of Experimental H and C NMR Chemical Shifts Applied to DFT Benchmarking.
Ryan D Cohen, Jared S Wood, Yu-Hong Lam, Alexei V Buevich, Edward C Sherer

Molecules· March 2023

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Quantitative nuclear magnetic resonance of chloride by an accurate internal standard approach.
Jared S Wood, Guilherme Dal Poggetto, Xiao Wang, Mikhail Reibarkh, R Thomas Williamson, Ryan D Cohen

Magn Reson Chem· January 2023

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Synthesis of L-cyclic tetrapeptides by backbone amide activation CyClick strategy.
Rachel Wills, Victor Adebomi, Caroline Spancake, Ryan D Cohen, Monika Raj

Tetrahedron· November 2022

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Application of 1,1-ADEQUATE and DFT to correct C misassignments of carbonyl chemical shifts for carbapenem antibiotics.
Ryan D Cohen, Xiao Wang, Edward C Sherer, Gary E Martin

Magn Reson Chem· October 2022

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Deuterated Modifiers in Sub/Supercritical Fluid Chromatography for Streamlined NMR Structure Elucidation.
Gioacchino Luca Losacco, Ryan D Cohen, Jimmy O DaSilva, Imad A Haidar Ahmad, Edward C Sherer

Anal Chem· September 2022

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A Diastereoselective Method for the Construction of -2'-Deoxy-2'-fluoronucleosides.
Michael T Pirnot, Edna Mao, Yu-Hong Lam, John Limanto, Ryan D Cohen

Org Lett· July 2022

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Trapping-Enrichment Multi-dimensional Liquid Chromatography with On-Line Deuterated Solvent Exchange for Streamlined Structure Elucidation at the Microgram Scale.
Imad A Haidar Ahmad, Gioacchino Luca Losacco, Vladimir Shchurik, Xiao Wang, Ryan D Cohen

Angew Chem Int Ed Engl· May 2022

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Selective Plate-Based Assay for Trace EDTA Analysis via Boron Trifluoride-methanol Derivatization UHPLC-QqQ-MS/MS Enabling Biologic and Vaccine Processes.
Raffeal Bennett, Ryan D Cohen, Heather Wang, Tony Pereira, Mark A Haverick

Anal Chem· January 2022

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Photoenzymatic Synthesis of α-Tertiary Amines by Engineered Flavin-Dependent "Ene"-Reductases.
Xin Gao, Joshua R Turek-Herman, Young Joo Choi, Ryan D Cohen, Todd K Hyster

J Am Chem Soc· December 2021

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Utilization of Metabolite Identification and Structural Data to Guide Design of Low-Dose IDO1 Inhibitors.
Brett Hopkins, Hongjun Zhang, Indu Bharathan, Derun Li, Qinglin Pu, Ryan D Cohen

ACS Med Chem Lett· September 2021

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Carbamate and -Pyrimidine Mitigate Amide Hydrolysis: Structure-Based Drug Design of Tetrahydroquinoline IDO1 Inhibitors.
Derun Li, Yongqi Deng, Abdelghani Achab, Indu Bharathan, Brett Andrew Hopkins, Ryan D Cohen

ACS Med Chem Lett· March 2021

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"One-Shot" Measurement of Residual Chemical Shift Anisotropy Using Poly-γ-benzyl-l-glutamate as an Alignment Medium.
Michael J J Recchia, Ryan D Cohen, Yizhou Liu, Edward C Sherer, James K Harper

Org Lett· November 2020

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A Multifunctional Reagent Designed for the Site-Selective Amination of Pyridines.
Patrick S Fier, Suhong Kim, Ryan D Cohen

J Am Chem Soc· May 2020

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Nine-Step Stereoselective Synthesis of Islatravir from Deoxyribose.
Christopher C Nawrat, Aaron M Whittaker, Mark A Huffman, Mark McLaughlin, Ryan D Cohen

Org Lett· March 2020

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Secondary amine selective Petasis (SASP) bioconjugation.
Yonnette E Sim, Ogonna Nwajiobi, Sriram Mahesh, Ryan D Cohen, Mikhail Y Reibarkh

Chem Sci· January 2020

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CyClick Chemistry for the Synthesis of Cyclic Peptides.
Victor Adebomi, Ryan D Cohen, Rachel Wills, Holland Andrew Hays Chavers, Gary E Martin

Angew Chem Int Ed Engl· December 2019

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Highly Diastereoselective Synthesis of a HCV NS5B Nucleoside Polymerase Inhibitor.
Yong-Li Zhong, Ed Cleator, Zhijian Liu, Jianguo Yin, William J Morris, Ryan D Cohen

J Org Chem· April 2019

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Synthesis of Cyanamides via a One-Pot Oxidation-Cyanation of Primary and Secondary Amines.
Nadine Kuhl, Saurin Raval, Ryan D Cohen

Org Lett· March 2019

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Discovery of a Photoinduced Dark Catalytic Cycle Using in Situ LED-NMR Spectroscopy.
Dan Lehnherr, Yining Ji, Andrew J Neel, Ryan D Cohen, Andrew P J Brunskill

J Am Chem Soc· October 2018

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Amino-Acid-Catalyzed Direct Aldol Bioconjugation.
Tiauna S Howard, Ryan D Cohen, Ogonna Nwajiobi, Zilma P Muneeswaran, Yonnette E Sim

Org Lett· September 2018

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