Publications by authors named "Ryan Randolph"

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Topical Treatment for Cutaneous Leishmaniasis: Dermato-Pharmacokinetic Lead Optimization of Benzoxaboroles.
Katrien Van Bocxlaer, Eric Gaukel, Deirdre Hauser, Seong Hee Park, Sara Schock, Ryan Randolph

Antimicrob Agents Chemother· May 2018

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Simulating Intestinal Transporter and Enzyme Activity in a Physiologically Based Pharmacokinetic Model for Tenofovir Disoproxil Fumarate.
Darren M Moss, Paul Domanico, Melynda Watkins, Seonghee Park, Ryan Randolph

Antimicrob Agents Chemother· July 2017

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Preclinical Pharmacokinetics and Pharmacodynamic Target of SCY-078, a First-in-Class Orally Active Antifungal Glucan Synthesis Inhibitor, in Murine Models of Disseminated Candidiasis.
Stephen A Wring, Ryan Randolph, SeongHee Park, George Abruzzo, Qing Chen

Antimicrob Agents Chemother· April 2017

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Development of a Novel Formulation That Improves Preclinical Bioavailability of Tenofovir Disoproxil Fumarate.
Melynda E Watkins, Steve Wring, Ryan Randolph, Seonghee Park, Kendall Powell

J Pharm Sci· March 2017

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Liver S9 Fraction-Derived Metabolites of Curcumin Analogue UBS109.
Terry W Moore, Shijun Zhu, Ryan Randolph, Mamoru Shoji, James P Snyder

ACS Med Chem Lett· April 2014

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Pharmacokinetics and pharmacodynamics utilizing unbound target tissue exposure as part of a disposition-based rationale for lead optimization of benzoxaboroles in the treatment of Stage 2 Human African Trypanosomiasis.
Stephen Wring, Eric Gaukel, Bakela Nare, Robert Jacobs, Beth Beaudet, Ryan Randolph

Parasitology· January 2014

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SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis.
Robert T Jacobs, Bakela Nare, Stephen A Wring, Matthew D Orr, Daitao Chen, Ryan Randolph

PLoS Negl Trop Dis· June 2011

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SAR of 2-amino and 2,4-diamino pyrimidines with in vivo efficacy against Trypanosoma brucei.
Joe B Perales, Jennifer Freeman, Cyrus J Bacchi, Tana Bowling, Robert Don, Ryan Randolph

Bioorg Med Chem Lett· May 2011

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Discovery of novel orally bioavailable oxaborole 6-carboxamides that demonstrate cure in a murine model of late-stage central nervous system african trypanosomiasis.
Bakela Nare, Stephen Wring, Cyrus Bacchi, Beth Beaudet, Tana Bowling, Ryan Randolph

Antimicrob Agents Chemother· October 2010

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