Publications by authors named "S Loughhead"

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Final outcomes analysis of the cell product SQZ-PBMC-HPV Phase 1 trial in incurable HPV16+ solid tumors shows improved overall survival in patients with increased CD8+ T cell tumor infiltration.
Alice N Weaver, Wade T Iams, Jong Chul Park, Monica Mita, Udo Holtick, Scott Loughhead

Mol Carcinog· August 2024

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Phase 1 study to determine the safety and dosing of autologous PBMCs modified to present HPV16 antigens (SQZ-PBMC-HPV) in HLA-A*02+ patients with HPV16+ solid tumors.
Antonio Jimeno, Joaquina Baranda, Wade T Iams, Jong Chul Park, Monica Mita, Scott M Loughhead

Invest New Drugs· April 2023

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Cell Squeeze: driving more effective CD8 T-cell activation through cytosolic antigen delivery.
J C Park, H Bernstein, S Loughhead, R Zwirtes, J Jennings

Immunooncol Technol· December 2022

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Engineered red blood cells (activating antigen carriers) drive potent T cell responses and tumor regression in mice.
Katarina Blagovic, Carolyne K Smith, Amritha Ramakrishnan, Lindsay Moore, David R Soto, Scott Loughhead

Front Immunol· October 2022

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Microfluidic Squeezing Enables MHC Class I Antigen Presentation by Diverse Immune Cells to Elicit CD8 T Cell Responses with Antitumor Activity.
Matthew G Booty, Kelan A Hlavaty, Adam Stockmann, Emrah Ilker Ozay, Carolyne Smith, Scott M Loughhead

J Immunol· February 2022

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