Publications by authors named "Saad Sammani"

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eNAMPT Is a Novel DAMP and Therapeutic Target in Human and Murine Pulmonary Fibrosis.
Nancy G Casanova, Jose D Herazo-Maya, Carrie L Kempf, Belinda L Sun, Jin H Song, Saad Sammani

Am J Respir Cell Mol Biol· October 2025

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eNAMPT/TLR4 signaling drives PAH cellular phenotypic switching and lung vascular remodeling.
Mohamed Ahmed, Shaira L Kee, Nahla Zaghloul, Nancy G Casanova, Marisela Rodriguez, Saad Sammani

Cell Commun Signal· October 2025

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Genetic and epigenetic regulation of cortactin (CTTN) by inflammatory factors and mechanical stress in human lung endothelial cells.
Xiaoguang Sun, Belinda Sun, Saad Sammani, Steven M Dudek, Patrick Belvitch

Biosci Rep· September 2024

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Circadian disruption dysregulates lung gene expression associated with inflammatory lung injury.
Nancy G Casanova, Richard L De Armond, Saad Sammani, Xiaoguang Sun, Belinda Sun

Front Immunol· April 2024

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TLR4 Ligation by eNAMPT, a Novel DAMP, is Essential to Sulfur Mustard- Induced Inflammatory Lung Injury and Fibrosis.
Carrie L Kempf, Jin H Song, Saad Sammani, Tadeo Bermudez, Vivian Reyes Hernon

Eur J Respir Med· February 2024

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An eNAMPT-neutralizing mAb reduces post-infarct myocardial fibrosis and left ventricular dysfunction.
Zhonglin Liu, Saad Sammani, Christy J Barber, Carrie L Kempf, Feng Li

Biomed Pharmacother· January 2024

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The impact of intravenous dodecafluoropentane on a murine model of acute lung injury.
Jarrod M Mosier, Saad Sammani, Carrie Kempf, Evan Unger, Joe G N Garcia

Intensive Care Med Exp· June 2023

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The eNAMPT/TLR4 inflammatory cascade drives the severity of intra-amniotic inflammation in pregnancy and predicts infant outcomes.
Mohamed Ahmed, Nancy G Casanova, Nahla Zaghloul, Akash Gupta, Marisela Rodriguez, Saad Sammani

Front Physiol· June 2023

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Targeting P-selectin glycoprotein ligand 1 in preclinical ARDS: Genetic and epigenetic regulation of the promoter.
Xiaoguang Sun, Saad Sammani, Matthew Hufford, Belinda L Sun, Carrie L Kempf

Pulm Circ· January 2023

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TLR4 activation induces inflammatory vascular permeability via Dock1 targeting and NOX4 upregulation.
Jin H Song, Joseph B Mascarenhas, Saad Sammani, Carrie L Kempf, Hua Cai

Biochim Biophys Acta Mol Basis Dis· December 2022

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Use of radiolabeled hyaluronic acid for preclinical assessment of inflammatory injury and acute respiratory distress syndrome.
Fangyuan Zhao, Christy J Barber, Saad Sammani, Li Wan, Brian W Miller

Nucl Med Biol· December 2022

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eNAMPT/TLR4 inflammatory cascade activation is a key contributor to SLE Lung vasculitis and alveolar hemorrhage.
Gantsetseg Tumurkhuu, Nancy G Casanova, Carrie L Kempf, Duygu Ercan Laguna, Sara M Camp, Saad Sammani

J Transl Autoimmun· December 2022

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Biochemical and genomic identification of novel biomarkers in progressive sarcoidosis: HBEGF, eNAMPT, and ANG-2.
Nancy G Casanova, Vivian Reyes-Hernon, Taylor Gregory, Belinda Sun, Tadeo Bermudez, Saad Sammani

Front Med (Lausanne)· October 2022

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A cortactin CTTN coding SNP contributes to lung vascular permeability and inflammatory disease severity in African descent subjects.
Patrick Belvitch, Nancy Casanova, Xiaoguang Sun, Sara M Camp, Saad Sammani

Transl Res· June 2022

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eNAMPT Neutralization Preserves Lung Fluid Balance and Reduces Acute Renal Injury in Porcine Sepsis/VILI-Induced Inflammatory Lung Injury.
Saad Sammani, Tadeo Bermudez, Carrie L Kempf, Jin H Song, Justin C Fleming

Front Physiol· June 2022

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eNAMPT Is a Novel Damage-associated Molecular Pattern Protein That Contributes to the Severity of Radiation-induced Lung Fibrosis.
Alexander N Garcia, Nancy G Casanova, Carrie L Kempf, Tadeo Bermudez, Daniel G Valera, Saad Sammani

Am J Respir Cell Mol Biol· May 2022

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Critical role for the lung endothelial nonmuscle myosin light-chain kinase isoform in the severity of inflammatory murine lung injury.
Carrie L Kempf, Saad Sammani, Tadeo Bermudez, Jin H Song, Vivian Reyes Hernon

Pulm Circ· April 2022

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Involvement of eNAMPT/TLR4 signaling in murine radiation pneumonitis: protection by eNAMPT neutralization.
Alexander N Garcia, Nancy G Casanova, Daniel G Valera, Xiaoguang Sun, Jin H Song, Saad Sammani

Transl Res· January 2022

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eNAMPT neutralization reduces preclinical ARDS severity via rectified NFkB and Akt/mTORC2 signaling.
Tadeo Bermudez, Saad Sammani, Jin H Song, Vivian Reyes Hernon, Carrie L Kempf

Sci Rep· January 2022

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Endothelial eNAMPT drives EndMT and preclinical PH: rescue by an eNAMPT-neutralizing mAb.
Mohamed Ahmed, Nahla Zaghloul, Prisca Zimmerman, Nancy G Casanova, Xiaoguang Sun, Saad Sammani

Pulm Circ· November 2021

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Endothelial eNAMPT amplifies pre-clinical acute lung injury: efficacy of an eNAMPT-neutralising monoclonal antibody.
Hector Quijada, Tadeo Bermudez, Carrie L Kempf, Daniel G Valera, Alexander N Garcia, Saad Sammani

Eur Respir J· May 2021

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UCHL1, a deubiquitinating enzyme, regulates lung endothelial cell permeability in vitro and in vivo.
Sumegha Mitra, Yulia Epshtein, Saad Sammani, Hector Quijada, Weiguo Chen

Am J Physiol Lung Cell Mol Physiol· April 2021

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Genetic and epigenetic regulation of the non-muscle myosin light chain kinase isoform by lung inflammatory factors and mechanical stress.
Xiaoguang Sun, Belinda L Sun, Saad Sammani, Tadeo Bermudez, Steven M Dudek

Clin Sci (Lond)· April 2021

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Direct Extracellular NAMPT Involvement in Pulmonary Hypertension and Vascular Remodeling. Transcriptional Regulation by SOX and HIF-2α.
Xiaoguang Sun, Belinda L Sun, Aleksandra Babicheva, Rebecca Vanderpool, Radu C Oita, Saad Sammani

Am J Respir Cell Mol Biol· July 2020

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RPA1 binding to NRF2 switches ARE-dependent transcriptional activation to ARE-NRE-dependent repression.
Pengfei Liu, Montserrat Rojo de la Vega, Saad Sammani, Joseph B Mascarenhas, Michael Kerins

Proc Natl Acad Sci U S A· October 2018

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