Publications by authors named "Sabine Lagger"

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Aging Reduces Intestinal Stem Cell Activity in Killifish and Intermittent Fasting Reverses Intestinal Gene Expression Patterns.
Michael Kothmayer, Sylvia Laffer, Philipp Widmayer, Elmar E Ebner, Fehima Ugarak, Sabine Lagger

Aging Cell· November 2025

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Cell-autonomous IL6ST activation suppresses prostate cancer development via STAT3/ARF/p53-driven senescence and confers an immune-active tumor microenvironment.
Christina Sternberg, Martin Raigel, Tanja Limberger, Karolína Trachtová, Michaela Schlederer, Sabine Lagger

Mol Cancer· October 2024

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JUN mediates the senescence associated secretory phenotype and immune cell recruitment to prevent prostate cancer progression.
Torben Redmer, Martin Raigel, Christina Sternberg, Roman Ziegler, Clara Probst, Sabine Lagger

Mol Cancer· May 2024

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STAT3/LKB1 controls metastatic prostate cancer by regulating mTORC1/CREB pathway.
Jan Pencik, Cecile Philippe, Michaela Schlederer, Emine Atas, Matteo Pecoraro, Sabine Lagger

Mol Cancer· August 2023

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KMT2C methyltransferase domain regulated INK4A expression suppresses prostate cancer metastasis.
Tanja Limberger, Michaela Schlederer, Karolina Trachtová, Ines Garces de Los Fayos Alonso, Jiaye Yang, Sabine Lagger

Mol Cancer· March 2022

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A STAT5B-CD9 axis determines self-renewal in hematopoietic and leukemic stem cells.
Sebastian Kollmann, Reinhard Grausenburger, Thorsten Klampfl, Michaela Prchal-Murphy, Klavdija Bastl, Sabine Lagger

Blood· December 2021

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DNA hypomethylation leads to cGAS-induced autoinflammation in the epidermis.
Mirjam A Beck, Heinz Fischer, Lisa M Grabner, Tamara Groffics, Mircea Winter, Sabine Lagger

EMBO J· November 2021

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Analysis of Methylation Dynamics Reveals a Tissue-Specific, Age-Dependent Decline in 5-Methylcytosine Within the Genome of the Vertebrate Aging Model .
Gordin Zupkovitz, Julijan Kabiljo, Michael Kothmayer, Katharina Schlick, Christian Schöfer, Sabine Lagger

Front Mol Biosci· June 2021

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Requirement of DNMT1 to orchestrate epigenomic reprogramming for NPM-ALK-driven lymphomagenesis.
Elisa Redl, Raheleh Sheibani-Tezerji, Crhistian de Jesus Cardona, Patricia Hamminger, Gerald Timelthaler, Sabine Lagger

Life Sci Alliance· February 2021

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STAT3-dependent analysis reveals PDK4 as independent predictor of recurrence in prostate cancer.
Monika Oberhuber, Matteo Pecoraro, Mate Rusz, Georg Oberhuber, Maritta Wieselberg, Sabine Lagger

Mol Syst Biol· April 2020

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Twins with different personalities: STAT5B-but not STAT5A-has a key role in BCR/ABL-induced leukemia.
Sebastian Kollmann, Eva Grundschober, Barbara Maurer, Wolfgang Warsch, Reinhard Grausenburger, Sabine Lagger

Leukemia· July 2019

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CDK6 coordinates mutant MPN via NF-κB and apoptotic networks.
Iris Z Uras, Barbara Maurer, Harini Nivarthi, Philipp Jodl, Karoline Kollmann, Sabine Lagger

Blood· April 2019

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Histone deacetylase 1 expression is inversely correlated with age in the short-lived fish Nothobranchius furzeri.
Gordin Zupkovitz, Sabine Lagger, David Martin, Marianne Steiner, Astrid Hagelkruys

Histochem Cell Biol· September 2018

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The Role of Activator Protein-1 (AP-1) Family Members in CD30-Positive Lymphomas.
Ines Garces de Los Fayos Alonso, Huan-Chang Liang, Suzanne D Turner, Sabine Lagger, Olaf Merkel

Cancers (Basel)· March 2018

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MeCP2 recognizes cytosine methylated tri-nucleotide and di-nucleotide sequences to tune transcription in the mammalian brain.
Sabine Lagger, John C Connelly, Gabriele Schweikert, Shaun Webb, Jim Selfridge

PLoS Genet· May 2017

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The molecular basis of variable phenotypic severity among common missense mutations causing Rett syndrome.
Kyla Brown, Jim Selfridge, Sabine Lagger, John Connelly, Dina De Sousa

Hum Mol Genet· February 2016

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CD4(+) T cell lineage integrity is controlled by the histone deacetylases HDAC1 and HDAC2.
Nicole Boucheron, Roland Tschismarov, Lisa Goeschl, Mirjam A Moser, Sabine Lagger

Nat Immunol· May 2014

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A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog.
Astrid Hagelkruys, Sabine Lagger, Julia Krahmer, Alexandra Leopoldi, Matthias Artaker

Development· February 2014

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Histone deacetylase inhibitor Trichostatin A induces neural tube defects and promotes neural crest specification in the chicken neural tube.
Christina Murko, Sabine Lagger, Marianne Steiner, Christian Seiser, Christian Schoefer

Differentiation· January 2013

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PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas.
Daniela Laimer, Helmut Dolznig, Karoline Kollmann, Paul W Vesely, Michaela Schlederer, Sabine Lagger

Nat Med· November 2012

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Self-organization phenomena in embryonic stem cell-derived embryoid bodies: axis formation and breaking of symmetry during cardiomyogenesis.
Christiane Fuchs, Matthias Scheinast, Waltraud Pasteiner, Sabine Lagger, Manuela Hofner

Cells Tissues Organs· September 2012

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Expression of class I histone deacetylases during chick and mouse development.
Christina Murko, Sabine Lagger, Marianne Steiner, Christian Seiser, Christian Schoefer

Int J Dev Biol· July 2011

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Distinct and redundant functions of histone deacetylases HDAC1 and HDAC2 in proliferation and tumorigenesis.
Jennifer Jurkin, Gordin Zupkovitz, Sabine Lagger, Reinhard Grausenburger, Astrid Hagelkruys

Cell Cycle· February 2011

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Crucial function of histone deacetylase 1 for differentiation of teratomas in mice and humans.
Sabine Lagger, Dominique Meunier, Mario Mikula, Reinhard Brunmeir, Michaela Schlederer

EMBO J· December 2010

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Epigenetic regulation of a murine retrotransposon by a dual histone modification mark.
Reinhard Brunmeir, Sabine Lagger, Elisabeth Simboeck, Anna Sawicka, Gerda Egger

PLoS Genet· April 2010

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