Publications by authors named "Sam Lievens"

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Pharmacological modulation of septins restores calcium homeostasis and is neuroprotective in models of Alzheimer's disease.
Katrien Princen, Tom Van Dooren, Marit van Gorsel, Nikolaos Louros, Xiaojuan Yang, Sam Lievens

Science· May 2024

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The Zinc-Finger Domain Containing Protein ZC4H2 Interacts with TRPV4, Enhancing Channel Activity and Turnover at the Plasma Membrane.
Laura Vangeel, Annelies Janssens, Irma Lemmens, Sam Lievens, Jan Tavernier

Int J Mol Sci· May 2020

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Nuclear import of the DSCAM-cytoplasmic domain drives signaling capable of inhibiting synapse formation.
Sonja M Sachse, Sam Lievens, Luís F Ribeiro, Dan Dascenco, Delphine Masschaele

EMBO J· March 2019

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KISS: A Mammalian Two-Hybrid Method for In Situ Analysis of Protein-Protein Interactions.
Delphine Masschaele, Sarah Gerlo, Irma Lemmens, Sam Lievens, Jan Tavernier

Methods Mol Biol· February 2019

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Modifying Rap1-signalling by targeting Pde6δ is neuroprotective in models of Alzheimer's disease.
Michael Dumbacher, Tom Van Dooren, Katrien Princen, Koen De Witte, Mélissa Farinelli, Sam Lievens

Mol Neurodegener· September 2018

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RNF41 interacts with the VPS52 subunit of the GARP and EARP complexes.
Delphine Masschaele, Leentje De Ceuninck, Joris Wauman, Dieter Defever, Frank Stenner, Sam Lievens

PLoS One· September 2017

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Glucocorticoid Receptor-mediated transactivation is hampered by Striatin-3, a novel interaction partner of the receptor.
Ioanna Petta, Nadia Bougarne, Jolien Vandewalle, Lien Dejager, Sofie Vandevyver, Sam Lievens

Sci Rep· August 2017

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MAPPI-DAT: data management and analysis for protein-protein interaction data from the high-throughput MAPPIT cell microarray platform.
Surya Gupta, Veronic De Puysseleyr, José Van der Heyden, Davy Maddelein, Irma Lemmens, Sam Lievens

Bioinformatics· May 2017

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Chromatin recruitment of activated AMPK drives fasting response genes co-controlled by GR and PPARα.
Dariusz Ratman, Viacheslav Mylka, Nadia Bougarne, Michal Pawlak, Sandrine Caron, Sam Lievens

Nucleic Acids Res· December 2016

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Proteome-scale Binary Interactomics in Human Cells.
Sam Lievens, José Van der Heyden, Delphine Masschaele, Leentje De Ceuninck, Ioanna Petta

Mol Cell Proteomics· December 2016

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Chemical Dimerizers in Three-Hybrid Systems for Small Molecule-Target Protein Profiling.
Dries J H De Clercq, Jan Tavernier, Sam Lievens, Serge Van Calenbergh

ACS Chem Biol· August 2016

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Ubiquitin D Regulates IRE1α/c-Jun N-terminal Kinase (JNK) Protein-dependent Apoptosis in Pancreatic Beta Cells.
Flora Brozzi, Sarah Gerlo, Fabio Arturo Grieco, Matilda Juusola, Alexander Balhuizen, Sam Lievens

J Biol Chem· June 2016

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The Interactome of the Glucocorticoid Receptor and Its Influence on the Actions of Glucocorticoids in Combatting Inflammatory and Infectious Diseases.
Ioanna Petta, Lien Dejager, Marlies Ballegeer, Sam Lievens, Jan Tavernier

Microbiol Mol Biol Rev· June 2016

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Modulation of Protein-Protein Interactions for the Development of Novel Therapeutics.
Ioanna Petta, Sam Lievens, Claude Libert, Jan Tavernier, Karolien De Bosscher

Mol Ther· April 2016

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Trapping mammalian protein complexes in viral particles.
Sven Eyckerman, Kevin Titeca, Emmy Van Quickelberghe, Eva Cloots, Annick Verhee, Sam Lievens

Nat Commun· April 2016

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OTUB1 triggers lung cancer development by inhibiting RAS monoubiquitination.
Maria Francesca Baietti, Michal Simicek, Layka Abbasi Asbagh, Enrico Radaelli, Sam Lievens

EMBO Mol Med· March 2016

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MAPPIT, a mammalian two-hybrid method for in-cell detection of protein-protein interactions.
Irma Lemmens, Sam Lievens, Jan Tavernier

Methods Mol Biol· December 2015

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Alternative reagents for methotrexate as immobilizing anchor moieties in the optimization of MASPIT: synthesis and biological evaluation.
Dries J H De Clercq, Martijn D P Risseeuw, Izet Karalic, Anne-Sophie De Smet, Dieter Defever, Sam Lievens

Chembiochem· March 2015

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MAPK-induced Gab1 translocation to the plasma membrane depends on a regulated intramolecular switch.
Alexandra Wolf, René Eulenfeld, Hannes Bongartz, Wiebke Hessenkemper, Philip C Simister, Sam Lievens

Cell Signal· February 2015

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Kinase Substrate Sensor (KISS), a mammalian in situ protein interaction sensor.
Sam Lievens, Sarah Gerlo, Irma Lemmens, Dries J H De Clercq, Martijn D P Risseeuw

Mol Cell Proteomics· December 2014

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A combined "omics" approach identifies N-Myc interactor as a novel cytokine-induced regulator of IRE1 protein and c-Jun N-terminal kinase in pancreatic beta cells.
Flora Brozzi, Sarah Gerlo, Fabio Arturo Grieco, Tarlliza Romanna Nardelli, Sam Lievens

J Biol Chem· July 2014

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Compound A, a selective glucocorticoid receptor modulator, enhances heat shock protein Hsp70 gene promoter activation.
Ilse M Beck, Zuzanna J Drebert, Ruben Hoya-Arias, Ali A Bahar, Michael Devos, Sam Lievens

PLoS One· April 2014

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The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response.
Michal Simicek, Sam Lievens, Mathias Laga, Dmytro Guzenko, Vasily N Aushev

Nat Cell Biol· October 2013

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A "clickable" MTX reagent as a practical tool for profiling small-molecule-intracellular target interactions via MASPIT.
Martijn D P Risseeuw, Dries J H De Clercq, Sam Lievens, Ulrik Hillaert, Davy Sinnaeve

ChemMedChem· March 2013

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The use of mammalian two-hybrid technologies for high-throughput drug screening.
Sam Lievens, Maureen Caligiuri, Niko Kley, Jan Tavernier

Methods· December 2012

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