Publications by authors named "Samuel Kilcher"

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Computational Pipeline for Targeted Integration and Variable Payload Expression in Bacteriophage Engineering.
Jonas Fernbach, Emese Hegedis, Martin J Loessner, Samuel Kilcher

ACS Synth Biol· October 2025

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CRISPR-Cas9 enables efficient genome engineering of the strictly lytic, broad-host-range staphylococcal bacteriophage K.
Jonas Fernbach, Jasmin Baggenstos, Ellen-Aleksandra Svorjova, Jeannine Riedo, Shawna McCallin, Samuel Kilcher

Appl Environ Microbiol· September 2025

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Heterodimerization of staphylococcal phage φ2638A endolysin isoforms and their functional role in bacterial lysis.
Léa V Zinsli, Anna M Sobieraj, Jiemin Du, Patrick Ernst, Susanne Meile, Samuel Kilcher

Microlife· June 2025

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Draft genome sequences of two wide-host-range phages of from food processing environments in the United States.
Phillip Brown, Samuel Kilcher, Jae-Won Kim, Martin Loessner, Sophia Kathariou

Microbiol Resour Announc· July 2024

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Genetic Engineering and Rebooting of Bacteriophages in L-Form Bacteria.
Jonas Fernbach, Susanne Meile, Samuel Kilcher, Martin J Loessner

Methods Mol Biol· December 2023

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Enhancing bacteriophage therapeutics through in situ production and release of heterologous antimicrobial effectors.
Jiemin Du, Susanne Meile, Jasmin Baggenstos, Tobias Jäggi, Pietro Piffaretti, Samuel Kilcher

Nat Commun· July 2023

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Engineered reporter phages for detection of Escherichia coli, Enterococcus, and Klebsiella in urine.
Susanne Meile, Jiemin Du, Samuel Staubli, Sebastian Grossmann, Hendrik Koliwer-Brandl, Samuel Kilcher

Nat Commun· July 2023

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L-form conversion in Gram-positive bacteria enables escape from phage infection.
Jan C Wohlfarth, Miki Feldmüller, Alissa Schneller, Samuel Kilcher, Marco Burkolter

Nat Microbiol· March 2023

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Engineering therapeutic phages for enhanced antibacterial efficacy.
Susanne Meile, Jiemin Du, Matthew Dunne, Samuel Kilcher, Martin J Loessner

Curr Opin Virol· February 2022

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Enhancing phage therapy through synthetic biology and genome engineering.
Bryan R Lenneman, Jonas Fernbach, Martin J Loessner, Timothy K Lu, Samuel Kilcher

Curr Opin Biotechnol· April 2021

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Reporter Phage-Based Detection of Bacterial Pathogens: Design Guidelines and Recent Developments.
Susanne Meile, Samuel Kilcher, Martin J Loessner, Matthew Dunne

Viruses· August 2020

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Listeria Phages Induce Cas9 Degradation to Protect Lysogenic Genomes.
Beatriz A Osuna, Shweta Karambelkar, Caroline Mahendra, Kathleen A Christie, Bianca Garcia, Samuel Kilcher

Cell Host Microbe· July 2020

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Critical Anti-CRISPR Locus Repression by a Bi-functional Cas9 Inhibitor.
Beatriz A Osuna, Shweta Karambelkar, Caroline Mahendra, Anne Sarbach, Matthew C Johnson, Samuel Kilcher

Cell Host Microbe· July 2020

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Engineered Reporter Phages for Rapid Bioluminescence-Based Detection and Differentiation of Viable Cells.
Susanne Meile, Anne Sarbach, Jiemin Du, Markus Schuppler, Carmen Saez, Samuel Kilcher

Appl Environ Microbiol· May 2020

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RNAi-Mediated Depletion of Poxvirus Proteins.
Caroline Martin, Samuel Kilcher

Methods Mol Biol· March 2020

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Phage resistance at the cost of virulence: Listeria monocytogenes serovar 4b requires galactosylated teichoic acids for InlB-mediated invasion.
Eric T Sumrall, Yang Shen, Anja P Keller, Jeanine Rismondo, Maria Pavlou, Samuel Kilcher

PLoS Pathog· October 2019

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Reprogramming Bacteriophage Host Range through Structure-Guided Design of Chimeric Receptor Binding Proteins.
Matthew Dunne, Beatrice Rupf, Marc Tala, Xhem Qabrati, Patrick Ernst, Samuel Kilcher

Cell Rep· October 2019

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Engineering Bacteriophages as Versatile Biologics.
Samuel Kilcher, Martin J Loessner

Trends Microbiol· April 2019

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Vaccinia virus hijacks EGFR signalling to enhance virus spread through rapid and directed infected cell motility.
Corina Beerli, Artur Yakimovich, Samuel Kilcher, Glennys V Reynoso, Gotthold Fläschner

Nat Microbiol· February 2019

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A functional type II-A CRISPR-Cas system from Listeria enables efficient genome editing of large non-integrating bacteriophage.
Mario Hupfeld, Despoina Trasanidou, Livia Ramazzini, Jochen Klumpp, Martin J Loessner, Samuel Kilcher

Nucleic Acids Res· July 2018

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Proteotype profiling unmasks a viral signalling network essential for poxvirus assembly and transcriptional competence.
Karel Novy, Samuel Kilcher, Ulrich Omasits, Christopher Karl Ernst Bleck, Corina Beerli

Nat Microbiol· May 2018

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Cross-genus rebooting of custom-made, synthetic bacteriophage genomes in L-form bacteria.
Samuel Kilcher, Patrick Studer, Christina Muessner, Jochen Klumpp, Martin J Loessner

Proc Natl Acad Sci U S A· January 2018

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3D printing of bacteria into functional complex materials.
Manuel Schaffner, Patrick A Rühs, Fergal Coulter, Samuel Kilcher, André R Studart

Sci Adv· December 2017

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Vaccinia Virus Infection Requires Maturation of Macropinosomes.
Zaira Rizopoulos, Giuseppe Balistreri, Samuel Kilcher, Caroline K Martin, Mohammedyaseen Syedbasha

Traffic· August 2015

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DNA virus uncoating.
Samuel Kilcher, Jason Mercer

Virology· May 2015

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