Publications by authors named "Sandra D Castillo"

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Verrucous venous malformation - subcutaneous variant mimicking other benign soft tissue tumors: a pediatric case series.
Camilo E Alarcón-Pérez, Carlota Rovira-Zurriaga, Marta Ivars, Sonia Paco, Cinzia Lavarino, Sandra D Castillo

Clin Exp Dermatol· December 2025

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Somatic Uniparental Disomy of PTEN in Endothelial Cells Causes Vascular Malformations in Patients with PTEN Hamartoma Tumor Syndrome.
Sandra D Castillo, Xabier Perosanz, Andrew K Ressler, Marta Ivars, Jairo Rodríguez

Cancer Discov· July 2025

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A class I PI3K signalling network regulates primary cilia disassembly in normal physiology and disease.
Sarah E Conduit, Wayne Pearce, Amandeep Bhamra, Benoit Bilanges, Laura Bozal-Basterra, Sandra D Castillo

Nat Commun· August 2024

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p53 rapidly restructures 3D chromatin organization to trigger a transcriptional response.
François Serra, Andrea Nieto-Aliseda, Lucía Fanlo-Escudero, Llorenç Rovirosa, Mónica Cabrera-Pasadas, Sandra D Castillo

Nat Commun· April 2024

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New genetic drivers in hemorrhagic hereditary telangiectasia.
Pau Cerdà, Sandra D Castillo, Cinthia Aguilera, Adriana Iriarte, José Luis Rocamora

Eur J Intern Med· January 2024

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PI3K-C2β limits mTORC1 signaling and angiogenic growth.
Piotr Kobialka, Judith Llena, Nerea Deleyto-Seldas, Margalida Munar-Gelabert, Jose A Dengra, Sandra D Castillo

Sci Signal· November 2023

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Immune-interacting lymphatic endothelial subtype at capillary terminals drives lymphatic malformation.
Milena Petkova, Marle Kraft, Simon Stritt, Ines Martinez-Corral, Henrik Ortsäter, Sandra D Castillo

J Exp Med· April 2023

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The onset of PI3K-related vascular malformations occurs during angiogenesis and is prevented by the AKT inhibitor miransertib.
Piotr Kobialka, Helena Sabata, Odena Vilalta, Leonor Gouveia, Ana Angulo-Urarte, Sandra D Castillo

EMBO Mol Med· July 2022

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Angiocrine polyamine production regulates adiposity.
Erika Monelli, Pilar Villacampa, Amaia Zabala-Letona, Anabel Martinez-Romero, Judith Llena, Sandra D Castillo

Nat Metab· March 2022

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Behavioural immune landscapes of inflammation.
Georgiana Crainiciuc, Miguel Palomino-Segura, Miguel Molina-Moreno, Jon Sicilia, David G Aragones, Sandra D Castillo

Nature· January 2022

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Blockade of VEGF-C signaling inhibits lymphatic malformations driven by oncogenic PIK3CA mutation.
Ines Martinez-Corral, Yan Zhang, Milena Petkova, Henrik Ortsäter, Sofie Sjöberg, Sandra D Castillo

Nat Commun· June 2020

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PIK3CA mutations in vascular malformations.
Sandra D Castillo, Eulalia Baselga, Mariona Graupera

Curr Opin Hematol· May 2019

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Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility.
Ana Angulo-Urarte, Pedro Casado, Sandra D Castillo, Piotr Kobialka, Maria Paraskevi Kotini

Nat Commun· November 2018

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Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling.
Inma M Berenjeno, Roberto Piñeiro, Sandra D Castillo, Wayne Pearce, Nicholas McGranahan

Nat Commun· November 2017

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Phosphoinositide 3-kinase: a new kid on the block in vascular anomalies.
Sandra D Castillo, Bart Vanhaesebroeck, Neil J Sebire

J Pathol· December 2016

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Somatic activating mutations in Pik3ca cause sporadic venous malformations in mice and humans.
Sandra D Castillo, Elena Tzouanacou, May Zaw-Thin, Inma M Berenjeno, Victoria E R Parker

Sci Transl Med· March 2016

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Determining the profiles and parameters for gene amplification testing of growth factor receptors in lung cancer.
Eva Pros, Sylvie Lantuejoul, Lydia Sanchez-Verde, Sandra D Castillo, Ester Bonastre

Int J Cancer· August 2013

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The SOX family of genes in cancer development: biological relevance and opportunities for therapy.
Sandra D Castillo, Montse Sanchez-Cespedes

Expert Opin Ther Targets· September 2012

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Novel transcriptional targets of the SRY-HMG box transcription factor SOX4 link its expression to the development of small cell lung cancer.
Sandra D Castillo, Ander Matheu, Niccolo Mariani, Julian Carretero, Fernando Lopez-Rios

Cancer Res· January 2012

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Gene amplification of the transcription factor DP1 and CTNND1 in human lung cancer.
Sandra D Castillo, Barbara Angulo, Ana Suarez-Gauthier, Lorenzo Melchor, Pedro P Medina

J Pathol· September 2010

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The SRY-HMG box gene, SOX4, is a target of gene amplification at chromosome 6p in lung cancer.
Pedro P Medina, Sandra D Castillo, Sandra Blanco, Marta Sanz-Garcia, Cristina Largo

Hum Mol Genet· April 2009

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