Publications by authors named "Sanjeev Redkar"

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Retraction: A New Class of Quinoline-Based DNA Hypomethylating Agents Reactivates Tumor Suppressor Genes by Blocking DNA Methyltransferase 1 Activity and Inducing Its Degradation.
Jharna Datta, Kalpana Ghoshal, William A Denny, Swarna A Gamage, Darby G Brooke, Sanjeev Redkar

Cancer Res· December 2023

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MET/HGF Coexpression as a Novel Predictive Biomarker for Response to MET Inhibitor Therapy in a Case of Psammomatous Melanotic Schwannoma.
Jenny J Li, Xiaoling Zhang, Neil Sankar, Lynn Espiritu, Sanjeev Redkar

JCO Precis Oncol· June 2022

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Erratum to: Targeting MET kinase with the small-molecule inhibitor amuvatinib induces cytotoxicity in primary myeloma cells and cell lines.
Cornel Joseph Phillip, Shadia Zaman, Shujun Shentu, Kumudha Balakrishnan, Jiexin Zhang, Sanjeev Redkar

J Hematol Oncol· October 2016

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Phase 1B study of amuvatinib in combination with five standard cancer therapies in adults with advanced solid tumors.
Monica Mita, Michael Gordon, Lee Rosen, Nirmal Kapoor, Gavin Choy, Sanjeev Redkar

Cancer Chemother Pharmacol· July 2014

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Design, synthesis, and pharmacological evaluation of fluorinated tetrahydrouridine derivatives as inhibitors of cytidine deaminase.
Dana Ferraris, Bridget Duvall, Greg Delahanty, Bipin Mistry, Jesse Alt, Sanjeev Redkar

J Med Chem· March 2014

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Targeting MET kinase with the small-molecule inhibitor amuvatinib induces cytotoxicity in primary myeloma cells and cell lines.
Cornel Joseph Phillip, Shadia Zaman, Shujun Shentu, Kumudha Balakrishnan, Jiexin Zhang, Sanjeev Redkar

J Hematol Oncol· December 2013

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Structure-activity relationships for 4-anilinoquinoline derivatives as inhibitors of the DNA methyltransferase enzyme DNMT1.
Swarna A Gamage, Darby G Brooke, Sanjeev Redkar, Jharna Datta, Samson T Jacob

Bioorg Med Chem· June 2013

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A phase I, first-in-human dose-escalation study of amuvatinib, a multi-targeted tyrosine kinase inhibitor, in patients with advanced solid tumors.
Raoul Tibes, Gil Fine, Gavin Choy, Sanjeev Redkar, Pietro Taverna

Cancer Chemother Pharmacol· February 2013

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Safety, tolerability, and pharmacokinetics of amuvatinib from three phase 1 clinical studies in healthy volunteers.
Gavin Choy, Rajashree Joshi-Hangal, Aram Oganesian, Gil Fine, Scott Rasmussen, Sanjeev Redkar

Cancer Chemother Pharmacol· July 2012

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Mechanisms of cytotoxicity to Pim kinase inhibitor, SGI-1776, in acute myeloid leukemia.
Lisa S Chen, Sanjeev Redkar, Pietro Taverna, Jorge E Cortes, Varsha Gandhi

Blood· July 2011

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Expect the unexpected-screen your screens.
Harish Ravivarapu, Sanjeev Redkar

J Pharm Sci· May 2011

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S110, a novel decitabine dinucleotide, increases fetal hemoglobin levels in baboons (P. anubis).
Donald Lavelle, Yogen Saunthararajah, Kestis Vaitkus, Mahipal Singh, Virryan Banzon, Sanjeev Redkar

J Transl Med· October 2010

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S110, a 5-Aza-2'-deoxycytidine-containing dinucleotide, is an effective DNA methylation inhibitor in vivo and can reduce tumor growth.
Jody C Chuang, Steven L Warner, David Vollmer, Hariprasad Vankayalapati, Sanjeev Redkar

Mol Cancer Ther· May 2010

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Pim kinase inhibitor, SGI-1776, induces apoptosis in chronic lymphocytic leukemia cells.
Lisa S Chen, Sanjeev Redkar, David Bearss, William G Wierda, Varsha Gandhi

Blood· November 2009

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Pharmacologic inhibition of Pim kinases alters prostate cancer cell growth and resensitizes chemoresistant cells to taxanes.
Shannon M Mumenthaler, Patricia Y B Ng, Amanda Hodge, David Bearss, Gregory Berk, Sanjeev Redkar

Mol Cancer Ther· October 2009

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A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation.
Jharna Datta, Kalpana Ghoshal, William A Denny, Swarna A Gamage, Darby G Brooke, Sanjeev Redkar

Cancer Res· May 2009

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Oral decitabine reactivates expression of the methylated gamma-globin gene in Papio anubis.
Donald Lavelle, Janet Chin, Kestis Vaitkus, Sanjeev Redkar, Pasit Phiasivongsa

Am J Hematol· November 2007

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Delivery of 5-aza-2'-deoxycytidine to cells using oligodeoxynucleotides.
Christine B Yoo, Shinwu Jeong, Gerda Egger, Gangning Liang, Pasit Phiasivongsa, Sanjeev Redkar

Cancer Res· July 2007

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Transbuccal delivery of 5-aza-2 -deoxycytidine: effects of drug concentration, buffer solution, and bile salts on permeation.
Ravichandran Mahalingam, Harish Ravivarapu, Sanjeev Redkar, Xiaoling Li, Bhaskara R Jasti

AAPS PharmSciTech· July 2007

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