Publications by authors named "Sara B Linker"

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Photoproximity labeling of c-Myc reveals SLK as a cancer specific co-regulator.
Ryan R Milione, Feifei Tong, Kelsey L Wolfe, Sara B Linker, Xinmeng Jasmine Mu

bioRxiv· October 2025

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Long interspersed nuclear elements safeguard neural progenitors from precocious differentiation.
Tomohisa Toda, Tracy A Bedrosian, Simon T Schafer, Michael S Cuoco, Sara B Linker

Cell Rep· February 2024

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Neuronal activity-related transcription is blunted in immature compared to mature dentate granule cells.
Sarah L Parylak, Fan Qiu, Sara B Linker, Iryna S Gallina, Christina K Lim

Hippocampus· April 2023

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Human-specific regulation of neural maturation identified by cross-primate transcriptomics.
Sara B Linker, Iñigo Narvaiza, Jonathan Y Hsu, Meiyan Wang, Fan Qiu

Curr Biol· November 2022

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Reduced synaptic activity and dysregulated extracellular matrix pathways in midbrain neurons from Parkinson's disease patients.
Shani Stern, Shong Lau, Andreea Manole, Idan Rosh, Menachem Mendel Percia, Sara B Linker

NPJ Parkinsons Dis· August 2022

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The role of retrotransposable elements in ageing and age-associated diseases.
Vera Gorbunova, Andrei Seluanov, Paolo Mita, Wilson McKerrow, David Fenyö, Sara B Linker

Nature· August 2021

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Deficient LEF1 expression is associated with lithium resistance and hyperexcitability in neurons derived from bipolar disorder patients.
Renata Santos, Sara B Linker, Shani Stern, Ana P D Mendes, Maxim N Shokhirev

Mol Psychiatry· June 2021

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Incorporation of a nucleoside analog maps genome repair sites in postmitotic human neurons.
Dylan A Reid, Patrick J Reed, Johannes C M Schlachetzki, Ioana I Nitulescu, Grace Chou, Sara B Linker

Science· April 2021

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Identification of bona fide B2 SINE retrotransposon transcription through single-nucleus RNA-seq of the mouse hippocampus.
Sara B Linker, Lynne Randolph-Moore, Kalyani Kottilil, Fan Qiu, Baptiste N Jaeger

Genome Res· November 2020

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IGF-1 treatment causes unique transcriptional response in neurons from individuals with idiopathic autism.
Sara B Linker, Ana P D Mendes, Maria C Marchetto

Mol Autism· June 2020

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Loss of the neural-specific BAF subunit ACTL6B relieves repression of early response genes and causes recessive autism.
Wendy Wenderski, Lu Wang, Andrey Krokhotin, Jessica J Walsh, Hongjie Li, Sara B Linker

Proc Natl Acad Sci U S A· May 2020

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Dynamical Electrical Complexity Is Reduced during Neuronal Differentiation in Autism Spectrum Disorder.
Debha N Amatya, Sara B Linker, Ana P D Mendes, Renata Santos, Galina Erikson

Stem Cell Reports· September 2019

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Species-specific maturation profiles of human, chimpanzee and bonobo neural cells.
Maria C Marchetto, Branka Hrvoj-Mihic, Bilal E Kerman, Diana X Yu, Krishna C Vadodaria, Sara B Linker

Elife· February 2019

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The role of adult hippocampal neurogenesis in brain health and disease.
Tomohisa Toda, Sarah L Parylak, Sara B Linker, Fred H Gage

Mol Psychiatry· January 2019

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BrainImageR: spatiotemporal gene set analysis referencing the human brain.
Sara B Linker, Jonathan Y Hsu, Adela Pfaff, Debha Amatya, Shu-Meng Ko

Bioinformatics· January 2019

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A novel environment-evoked transcriptional signature predicts reactivity in single dentate granule neurons.
Baptiste N Jaeger, Sara B Linker, Sarah L Parylak, Jerika J Barron, Iryna S Gallina

Nat Commun· August 2018

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Evaluating different DNA binding domains to modulate L1 ORF2p-driven site-specific retrotransposition events in human cells.
Catherine M Ade, Rebecca S Derbes, Bradley J Wagstaff, Sara B Linker, Travis B White

Gene· February 2018

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Nup153 Interacts with Sox2 to Enable Bimodal Gene Regulation and Maintenance of Neural Progenitor Cells.
Tomohisa Toda, Jonathan Y Hsu, Sara B Linker, Lauren Hu, Simon T Schafer

Cell Stem Cell· November 2017

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Examining non-LTR retrotransposons in the context of the evolving primate brain.
Sara B Linker, Maria C Marchetto, Iñigo Narvaiza, Ahmet M Denli, Fred H Gage

BMC Biol· August 2017

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Corrigendum: Nuclear RNA-seq of single neurons reveals molecular signatures of activation.
Benjamin Lacar, Sara B Linker, Baptiste N Jaeger, Suguna Rani Krishnaswami, Jerika J Barron

Nat Commun· March 2017

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Corrigendum: Nuclear RNA-seq of single neurons reveals molecular signatures of activation.
Benjamin Lacar, Sara B Linker, Baptiste N Jaeger, Suguna Rani Krishnaswami, Jerika J Barron

Nat Commun· June 2016

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Nuclear RNA-seq of single neurons reveals molecular signatures of activation.
Benjamin Lacar, Sara B Linker, Baptiste N Jaeger, Suguna R Krishnaswami, Jerika J Barron

Nat Commun· April 2016

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Using single nuclei for RNA-seq to capture the transcriptome of postmortem neurons.
Suguna Rani Krishnaswami, Rashel V Grindberg, Mark Novotny, Pratap Venepally, Benjamin Lacar, Sara B Linker

Nat Protoc· March 2016

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