Publications by authors named "Sara Colombetti"

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T cell margination: investigating the detour of T cells following forimtamig treatment in humanized mice.
Nils O'Brien, Joerg P J Mueller, Ann-Marie E Bröske, Jan Attig, Franz Osl, Sara Colombetti

MAbs· December 2025

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Optimizing efficacy and safety of T cell bispecific antibodies: the interdependence of CD3 and tumor antigen binder affinities in FOLR1 and CEACAM5 2 + 1 TCBs.
Omar Abdelmotaleb, Anneliese Schneider, Inja Waldhauer, Johannes Sam, Thomas Hofer, Sara Colombetti

MAbs· December 2025

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CEA-4-1BBL: CEACAM5-Targeted 4-1BB Ligand Fusion Proteins for Cis Co-Stimulation with CEA-TCB.
Christina Claus, Claudia Ferrara-Koller, Johannes Sam, Sabine Lang, Rosmarie Albrecht, Sara Colombetti

Antibodies (Basel)· November 2025

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Preclinical advances in glofitamab combinations: a new frontier for non-Hodgkin lymphoma.
Johannes Sam, Gabrielle Leclercq-Cohen, Samuel Gebhardt, Marlena Surowka, Sylvia Herter, Sara Colombetti

Blood· October 2025

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CD19-CD28: an affinity-optimized CD28 agonist for combination with glofitamab (CD20-TCB) as off-the-shelf immunotherapy.
Johannes Sam, Thomas Hofer, Christine Kuettel, Christina Claus, Jenny Thom, Sara Colombetti

Blood· May 2024

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Combining venetoclax and azacytidine with T-cell bispecific antibodies for treatment of acute myeloid leukemia: a preclinical assessment.
Gerulf Hänel, Anne Schönle, Anne-Sophie Neumann, Daniel Nixdorf, Nora Philipp, Sara Colombetti

Leukemia· February 2024

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ROCKETS - a novel one-for-all toolbox for light sheet microscopy in drug discovery.
Joerg P J Mueller, Michael Dobosz, Nils O'Brien, Nassri Abdoush, Anna Maria Giusti, Sara Colombetti

Front Immunol· February 2023

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A Novel EGFRvIII T-Cell Bispecific Antibody for the Treatment of Glioblastoma.
Raffaella Iurlaro, Inja Waldhauer, Ester Planas-Rigol, Ester Bonfill-Teixidor, Alexandra Arias, Sara Colombetti

Mol Cancer Ther· October 2022

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PD-1-cis IL-2R agonism yields better effectors from stem-like CD8 T cells.
Laura Codarri Deak, Valeria Nicolini, Masao Hashimoto, Maria Karagianni, Petra C Schwalie, Sara Colombetti

Nature· October 2022

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Simlukafusp alfa (FAP-IL2v) immunocytokine is a versatile combination partner for cancer immunotherapy.
Inja Waldhauer, Valeria Gonzalez-Nicolini, Anne Freimoser-Grundschober, Tapan K Nayak, Linda Fahrni, Sara Colombetti

MAbs· December 2021

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Multi-Parameter Quantitative Imaging of Tumor Microenvironments Reveals Perivascular Immune Niches Associated With Anti-Tumor Immunity.
Caleb R Stoltzfus, Ramya Sivakumar, Leo Kunz, Brandy E Olin Pope, Elena Menietti, Sara Colombetti

Front Immunol· November 2021

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International Consensus on Minimum Preclinical Testing Requirements for the Development of Innovative Therapies For Children and Adolescents with Cancer.
Gilles Vassal, Peter J Houghton, Stefan M Pfister, Malcolm A Smith, Huib N Caron, Sara Colombetti

Mol Cancer Ther· August 2021

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Cross-linking of T cell to B cell lymphoma by the T cell bispecific antibody CD20-TCB induces IFNγ/CXCL10-dependent peripheral T cell recruitment in humanized murine model.
Floriana Cremasco, Elena Menietti, Dario Speziale, Johannes Sam, Stefano Sammicheli, Sara Colombetti

PLoS One· April 2021

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Corrigendum: Combination of T-Cell Bispecific Antibodies With PD-L1 Checkpoint Inhibition Elicits Superior Anti-Tumor Activity.
Johannes Sam, Sara Colombetti, Tanja Fauti, Andreas Roller, Marlene Biehl

Front Oncol· February 2021

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Combination of T-Cell Bispecific Antibodies With PD-L1 Checkpoint Inhibition Elicits Superior Anti-Tumor Activity.
Johannes Sam, Sara Colombetti, Tanja Fauti, Andreas Roller, Marlene Biehl

Front Oncol· November 2020

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Dendritic cells dictate responses to PD-L1 blockade cancer immunotherapy.
Maud Mayoux, Andreas Roller, Vesna Pulko, Stefano Sammicheli, Stanford Chen, Sara Colombetti

Sci Transl Med· March 2020

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Tumor-targeted 4-1BB agonists for combination with T cell bispecific antibodies as off-the-shelf therapy.
Christina Claus, Claudia Ferrara, Wei Xu, Johannes Sam, Sabine Lang, Sara Colombetti

Sci Transl Med· June 2019

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CD20-TCB with Obinutuzumab Pretreatment as Next-Generation Treatment of Hematologic Malignancies.
Marina Bacac, Sara Colombetti, Sylvia Herter, Johannes Sam, Mario Perro

Clin Cancer Res· October 2018

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In Vivo Fluorescence Imaging of the Activity of CEA TCB, a Novel T-Cell Bispecific Antibody, Reveals Highly Specific Tumor Targeting and Fast Induction of T-Cell-Mediated Tumor Killing.
Steffi Lehmann, Ramanil Perera, Hans-Peter Grimm, Johannes Sam, Sara Colombetti

Clin Cancer Res· September 2016

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Application of a MABEL Approach for a T-Cell-Bispecific Monoclonal Antibody: CEA TCB.
Sherri Dudal, Heather Hinton, Anna M Giusti, Marina Bacac, Magali Muller, Sara Colombetti

J Immunother· September 2016

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A Novel Carcinoembryonic Antigen T-Cell Bispecific Antibody (CEA TCB) for the Treatment of Solid Tumors.
Marina Bacac, Tanja Fauti, Johannes Sam, Sara Colombetti, Tina Weinzierl

Clin Cancer Res· July 2016

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Breast cancer suppressor candidate-1 (BCSC-1) is a melanoma tumor suppressor that down regulates MITF.
Silvia I Anghel, Rafael Correa-Rocha, Eva Budinska, Kayluz F Boligan, Shahnaz Abraham, Sara Colombetti

Pigment Cell Melanoma Res· July 2012

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Rapamycin-sensitive signals control TCR/CD28-driven Ifng, Il4 and Foxp3 transcription and promoter region methylation.
Romana Tomasoni, Veronica Basso, Karolina Pilipow, Giovanni Sitia, Simona Saccani, Sara Colombetti

Eur J Immunol· July 2011

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IL-7 adjuvant treatment enhances long-term tumor-antigen-specific CD8+ T-cell responses after immunization with recombinant lentivector.
Sara Colombetti, Frédéric Lévy, Laurence Chapatte

Blood· June 2009

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Lentivector immunization induces tumor antigen-specific B and T cell responses in vivo.
Javier Garcia Casado, Jozef Janda, Joe Wei, Laurence Chapatte, Sara Colombetti

Eur J Immunol· July 2008

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