Publications by authors named "Sara Simonelli"

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Abdominal obesity negatively influences key metrics of reverse cholesterol transport.
Jennifer Härdfeldt, Marica Cariello, Sara Simonelli, Alice Ossoli, Natasha Scialpi

Biochim Biophys Acta Mol Cell Biol Lipids· February 2022

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CER-001 ameliorates lipid profile and kidney disease in a mouse model of familial LCAT deficiency.
Alice Ossoli, Arianna Strazzella, Daniela Rottoli, Cristina Zanchi, Monica Locatelli, Sara Simonelli

Metabolism· March 2021

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The Association between HDL-C and Subclinical Atherosclerosis Depends on CETP Plasma Concentration: Insights from the IMPROVE Study.
Gualtiero I Colombo, Vanessa Bianconi, Alice Bonomi, Sara Simonelli, Mauro Amato

Biomedicines· March 2021

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Activation of Naturally Occurring Lecithin:Cholesterol Acyltransferase Mutants by a Novel Activator Compound.
Chiara Pavanello, Alice Ossoli, Marta Turri, Arianna Strazzella, Sara Simonelli

J Pharmacol Exp Ther· December 2020

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Low Plasma Lecithin: Cholesterol Acyltransferase (LCAT) Concentration Predicts Chronic Kidney Disease.
Andrea Baragetti, Alice Ossoli, Arianna Strazzella, Sara Simonelli, Ivano Baragetti

J Clin Med· July 2020

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Paradoxical fall in proteinuria during pregnancy in an LCAT-deficient patient-A case report.
Elinor V Hanna, Sara Simonelli, Sarah Chamney, Alice Ossoli, Robert N Mullan

J Clin Lipidol· October 2019

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Recombinant LCAT (Lecithin:Cholesterol Acyltransferase) Rescues Defective HDL (High-Density Lipoprotein)-Mediated Endothelial Protection in Acute Coronary Syndrome.
Alice Ossoli, Sara Simonelli, Marisa Varrenti, Nuccia Morici, Fabrizio Oliva

Arterioscler Thromb Vasc Biol· May 2019

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The Extent of Human Apolipoprotein A-I Lipidation Strongly Affects the β-Amyloid Efflux Across the Blood-Brain Barrier .
Roberta Dal Magro, Sara Simonelli, Alysia Cox, Beatrice Formicola, Roberta Corti

Front Neurosci· May 2019

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A proteomic approach to identify novel disease biomarkers in LCAT deficiency.
Sara Simonelli, Alice Ossoli, Cristina Banfi, Chiara Pavanello, Laura Calabresi

J Proteomics· April 2019

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Topiramate protects apoE-deficient mice from kidney damage without affecting plasma lipids.
Stefano Manzini, Marco Busnelli, Cinzia Parolini, Lucia Minoli, Alice Ossoli, Sara Simonelli

Pharmacol Res· March 2019

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Complete and Partial Lecithin:Cholesterol Acyltransferase Deficiency Is Differentially Associated With Atherosclerosis.
Federico Oldoni, Damiano Baldassarre, Samuela Castelnuovo, Alice Ossoli, Mauro Amato, Sara Simonelli

Circulation· September 2018

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Plasma PCSK9 levels and lipoprotein distribution are preserved in carriers of genetic HDL disorders.
Massimiliano Ruscica, Sara Simonelli, Margherita Botta, Alice Ossoli, Maria Giovanna Lupo

Biochim Biophys Acta Mol Cell Biol Lipids· September 2018

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Indicators of Cardiovascular Risk in Metabolic Syndrome: Long Term Follow-up in Italian Patients.
Giuliana Mombelli, Chiara Pavanello, Samuela Castelnuovo, Raffaella Bosisio, Sara Simonelli

Curr Vasc Pharmacol· December 2017

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Depletion in LpA-I:A-II particles enhances HDL-mediated endothelial protection in familial LCAT deficiency.
Monica Gomaraschi, Alice Ossoli, Samuela Castelnuovo, Sara Simonelli, Chiara Pavanello

J Lipid Res· May 2017

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Persistent changes in lipoprotein lipids after a single infusion of ascending doses of MDCO-216 (apoA-IMilano/POPC) in healthy volunteers and stable coronary artery disease patients.
Herman J Kempen, Monica Gomaraschi, Sara Simonelli, Laura Calabresi, Matthijs Moerland

Atherosclerosis· December 2016

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Role of LCAT in Atherosclerosis.
Alice Ossoli, Sara Simonelli, Cecilia Vitali, Guido Franceschini, Laura Calabresi

J Atheroscler Thromb· November 2016

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Distant homology modeling of LCAT and its validation through in silico targeting and in vitro and in vivo assays.
Cristina Sensi, Sara Simonelli, Ilaria Zanotti, Gabriella Tedeschi, Giulia Lusardi

PLoS One· January 2015

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HDL and atherosclerosis: Insights from inherited HDL disorders.
Laura Calabresi, Monica Gomaraschi, Sara Simonelli, Franco Bernini, Guido Franceschini

Biochim Biophys Acta· January 2015

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Differential effects of fenofibrate and extended-release niacin on high-density lipoprotein particle size distribution and cholesterol efflux capacity in dyslipidemic patients.
Guido Franceschini, Elda Favari, Laura Calabresi, Sara Simonelli, Alighiero Bondioli

J Clin Lipidol· October 2014

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Recombinant human LCAT normalizes plasma lipoprotein profile in LCAT deficiency.
Sara Simonelli, Cristina Tinti, Laura Salvini, Laura Tinti, Alice Ossoli

Biologicals· November 2013

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A woman with low HDL cholesterol and corneal opacity.
Tiziano Lucchi, Laura Calabresi, Angela Pinto, Elisa Benetti, Beatrice Arosio, Sara Simonelli

Intern Emerg Med· December 2012

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Novel missense variants in LCAT and APOB genes in an Italian kindred with familial lecithin:cholesterol acyltransferase deficiency and hypobetalipoproteinemia.
Paola Conca, Silvana Pileggi, Sara Simonelli, Emanuela Boer, Giuliano Boscutti

J Clin Lipidol· September 2012

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Genetic lecithin:cholesterol acyltransferase deficiency and cardiovascular disease.
Laura Calabresi, Sara Simonelli, Monica Gomaraschi, Guido Franceschini

Atherosclerosis· June 2012

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Characterization of three kindreds with familial combined hypolipidemia caused by loss-of-function mutations of ANGPTL3.
Livia Pisciotta, Elda Favari, Lucia Magnolo, Sara Simonelli, Maria Pia Adorni

Circ Cardiovasc Genet· February 2012

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Severe high-density lipoprotein deficiency associated with autoantibodies against lecithin:cholesterol acyltransferase in non-Hodgkin lymphoma.
Sara Simonelli, Elisabetta Gianazza, Giuliana Mombelli, Alighiero Bondioli, Giovanni Ferraro

Arch Intern Med· January 2012

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