Publications by authors named "Sarah Roche"

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A peer-volunteer led active ageing programme to prevent decline in physical function in older people at risk of mobility disability (Active, Connected, Engaged [ACE]): study protocol for a randomised controlled trial.
Afroditi Stathi, Janet Withall, Diane Crone, Helen Hawley-Hague, Rebecca Playle, Sarah Roche

Trials· November 2023

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Migraine-attributed burden, impact and disability, and migraine-impacted quality of life: Expert consensus on definitions from a Delphi process.
Timothy J Steiner, Gisela M Terwindt, Zaza Katsarava, Patricia Pozo-Rosich, Andreas R Gantenbein, Sarah L Roche

Cephalalgia· November 2022

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Childhood neighborhoods and health: Census-based neighborhood measures versus residential lived experiences.
Sarah Roche, Amy Spring, Alexus Moore

Health Place· November 2022

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Prevalence Rates of Primary Headache Disorders and Evaluation and Treatment Patterns Among Korean Neurologists.
Byung-Kun Kim, Min Kyung Chu, Soo Jin Yu, Grazia Dell'Agnello, Hans-Peter Hundemer, Sarah Louise Roche

J Clin Neurol· September 2022

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Glycaemic variability in patients with type 2 diabetes mellitus treated with dulaglutide, with and without concomitant insulin: Post hoc analyses of randomized clinical trials.
Esteban Jódar, Irene Romera, Qianqian Wang, Sarah Louise Roche, Luis-Emilio García-Pérez

Diabetes Obes Metab· April 2022

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Rod Photoreceptor Neuroprotection in Dark-Reared Pde6brd10 Mice.
Bruce A Berkowitz, Robert H Podolsky, Karen Lins Childers, Sarah L Roche, Thomas G Cotter

Invest Ophthalmol Vis Sci· November 2020

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Selective Histone Deacetylase 6 Inhibitors Restore Cone Photoreceptor Vision or Outer Segment Morphology in Zebrafish and Mouse Models of Retinal Blindness.
Husvinee Sundaramurthi, Sarah L Roche, Guinevere L Grice, Ailis Moran, Eugene T Dillion

Front Cell Dev Biol· August 2020

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Norgestrel, a Progesterone Analogue, Promotes Significant Long-Term Neuroprotection of Cone Photoreceptors in a Mouse Model of Retinal Disease.
Sarah L Roche, Oksana Kutsyr, Nicolás Cuenca, Thomas G Cotter

Invest Ophthalmol Vis Sci· July 2019

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Cell Death Analysis in Retinal Cultures.
Sarah L Roche, Ana M Ruiz-Lopez, Thomas G Cotter

Methods Mol Biol· April 2019

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Microglial-induced Müller cell gliosis is attenuated by progesterone in a mouse model of retinitis pigmentosa.
Sarah L Roche, Ana M Ruiz-Lopez, Jennifer N Moloney, Ashleigh M Byrne, Thomas G Cotter

Glia· February 2018

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Alterations to retinal architecture prior to photoreceptor loss in a mouse model of retinitis pigmentosa.
Sarah L Roche, Alice C Wyse-Jackson, Ashleigh M Byrne, Ana M Ruiz-Lopez, Thomas G Cotter

Int J Dev Biol· January 2018

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Nuclear membrane-localised NOX4D generates pro-survival ROS in FLT3-ITD-expressing AML.
Jennifer N Moloney, Ashok Kumar Jayavelu, Joanna Stanicka, Sarah L Roche, Rebecca L O'Brien

Oncotarget· December 2017

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Pro-survival redox signalling in progesterone-mediated retinal neuroprotection.
Ana M Ruiz Lopez, Sarah L Roche, Alice C Wyse Jackson, Jennifer N Moloney, Ashleigh M Byrne

Eur J Neurosci· July 2017

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Progesterone Attenuates Microglial-Driven Retinal Degeneration and Stimulates Protective Fractalkine-CX3CR1 Signaling.
Sarah L Roche, Alice C Wyse-Jackson, Violeta Gómez-Vicente, Pedro Lax, Ana M Ruiz-Lopez

PLoS One· June 2017

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Fractalkine-CX3CR1 signaling is critical for progesterone-mediated neuroprotection in the retina.
Sarah L Roche, Alice C Wyse-Jackson, Ana M Ruiz-Lopez, Ashleigh M Byrne, Thomas G Cotter

Sci Rep· February 2017

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The synthetic progestin norgestrel modulates Nrf2 signaling and acts as an antioxidant in a model of retinal degeneration.
Ashleigh M Byrne, Ana M Ruiz-Lopez, Sarah L Roche, Jennifer N Moloney, Alice C Wyse-Jackson

Redox Biol· December 2016

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Progesterone analogue protects stressed photoreceptors via bFGF-mediated calcium influx.
Alice C Wyse-Jackson, Sarah L Roche, Ana M Ruiz-Lopez, Jennifer N Moloney, Ashleigh M Byrne

Eur J Neurosci· December 2016

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The synthetic progestin norgestrel acts to increase LIF levels in the rd10 mouse model of retinitis pigmentosa.
Ashleigh M Byrne, Sarah L Roche, Ana M Ruiz-Lopez, Alice C Wyse Jackson, Thomas G Cotter

Mol Vis· November 2016

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Progesterone receptor signalling in retinal photoreceptor neuroprotection.
Alice C Wyse Jackson, Sarah L Roche, Ashleigh M Byrne, Ana M Ruiz-Lopez, Thomas G Cotter

J Neurochem· January 2016

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The influence of storage parameters on measurement of survival motor neuron (SMN) protein levels: implications for pre-clinical studies and clinical trials for spinal muscular atrophy.
Gillian Hunter, Sarah L Roche, Eilidh Somers, Heidi R Fuller, Thomas H Gillingwater

Neuromuscul Disord· November 2014

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Loss of glial neurofascin155 delays developmental synapse elimination at the neuromuscular junction.
Sarah L Roche, Diane L Sherman, Kosala Dissanayake, Geneviève Soucy, Anne Desmazieres

J Neurosci· September 2014

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Canonical BMP-Smad signalling promotes neurite growth in rat midbrain dopaminergic neurons.
Shane V Hegarty, Louise M Collins, Aisling M Gavin, Sarah L Roche, Sean L Wyatt

Neuromolecular Med· June 2014

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A novel mouse model of Warburg Micro syndrome reveals roles for RAB18 in eye development and organisation of the neuronal cytoskeleton.
Sarah M Carpanini, Lisa McKie, Derek Thomson, Ann K Wright, Sarah L Gordon, Sarah L Roche

Dis Model Mech· June 2014

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SMN-dependent intrinsic defects in Schwann cells in mouse models of spinal muscular atrophy.
Gillian Hunter, Arwin Aghamaleky Sarvestany, Sarah L Roche, Rebecca C Symes, Thomas H Gillingwater

Hum Mol Genet· May 2014

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Dysregulation of ubiquitin homeostasis and β-catenin signaling promote spinal muscular atrophy.
Thomas M Wishart, Chantal A Mutsaers, Markus Riessland, Michell M Reimer, Gillian Hunter, Sarah L Roche

J Clin Invest· April 2014

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