Publications by authors named "Scott A Busby"

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Advancements in Assay Technologies and Strategies to Enable Drug Discovery.
Scott A Busby, Seth Carbonneau, John Concannon, Christoph E Dumelin, YounKyoung Lee

ACS Chem Biol· October 2020

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Structure based design of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors from a phenotypic screen.
Daniel S Palacios, Erik Meredith, Toshio Kawanami, Christopher Adams, Xin Chen, Scott A Busby

Bioorg Med Chem Lett· February 2018

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Identifying initiation and elongation inhibitors of dengue virus RNA polymerase in a high-throughput lead-finding campaign.
Thomas M Smith, Siew Pheng Lim, Kimberley Yue, Scott A Busby, Rishi Arora

J Biomol Screen· January 2015

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Activation of AMP-activated protein kinase revealed by hydrogen/deuterium exchange mass spectrometry.
Rachelle R Landgraf, Devrishi Goswami, Francis Rajamohan, Melissa S Harris, Matthew F Calabrese, Scott A Busby

Structure· November 2013

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Targeting orphan nuclear receptors for treatment of metabolic diseases and autoimmunity.
Thomas P Burris, Scott A Busby, Patrick R Griffin

Chem Biol· January 2012

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Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation.
Jang Hyun Choi, Alexander S Banks, Theodore M Kamenecka, Scott A Busby, Michael J Chalmers

Nature· September 2011

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Identification of a novel non-retinoid pan inverse agonist of the retinoic acid receptors.
Scott A Busby, Naresh Kumar, Dana S Kuruvilla, Monica A Istrate, Juliana J Conkright

ACS Chem Biol· June 2011

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DNA binding alters coactivator interaction surfaces of the intact VDR-RXR complex.
Jun Zhang, Michael J Chalmers, Keith R Stayrook, Lorri L Burris, Yongjun Wang, Scott A Busby

Nat Struct Mol Biol· May 2011

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A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects.
Jae Man Lee, Yoon Kwang Lee, Jennifer L Mamrosh, Scott A Busby, Patrick R Griffin

Nature· May 2011

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Differential hydrogen/deuterium exchange mass spectrometry analysis of protein-ligand interactions.
Michael J Chalmers, Scott A Busby, Bruce D Pascal, Graham M West, Patrick R Griffin

Expert Rev Proteomics· February 2011

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A combined ligand- and structure-based virtual screening protocol identifies submicromolar PPARγ partial agonists.
Dušica Vidović, Scott A Busby, Patrick R Griffin, Stephan C Schürer

ChemMedChem· January 2011

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Helix 11 dynamics is critical for constitutive androstane receptor activity.
Edward Wright, Scott A Busby, Sarah Wisecarver, Jeremy Vincent, Patrick R Griffin

Structure· January 2011

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The benzenesulfoamide T0901317 [N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide] is a novel retinoic acid receptor-related orphan receptor-alpha/gamma inverse agonist.
Naresh Kumar, Laura A Solt, Juliana J Conkright, Yongjun Wang, Monica A Istrate, Scott A Busby

Mol Pharmacol· February 2010

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Identification of specific hemopexin-like domain residues that facilitate matrix metalloproteinase collagenolytic activity.
Janelle L Lauer-Fields, Michael J Chalmers, Scott A Busby, Dmitriy Minond, Patrick R Griffin

J Biol Chem· September 2009

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Apo-human carbonic anhydrase II revisited: implications of the loss of a metal in protein structure, stability, and solvent network.
Balendu Sankara Avvaru, Scott A Busby, Michael J Chalmers, Patrick R Griffin, Balasubramanian Venkatakrishnan

Biochemistry· August 2009

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HD desktop: an integrated platform for the analysis and visualization of H/D exchange data.
Bruce D Pascal, Michael J Chalmers, Scott A Busby, Patrick R Griffin

J Am Soc Mass Spectrom· April 2009

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Partial agonists activate PPARgamma using a helix 12 independent mechanism.
John B Bruning, Michael J Chalmers, Swati Prasad, Scott A Busby, Theodore M Kamenecka

Structure· October 2007

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A two-stage differential hydrogen deuterium exchange method for the rapid characterization of protein/ligand interactions.
Michael J Chalmers, Scott A Busby, Bruce D Pascal, Mark R Southern, Patrick R Griffin

J Biomol Tech· September 2007

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Chemical derivatization of histones for facilitated analysis by mass spectrometry.
Benjamin A Garcia, Sahana Mollah, Beatrix M Ueberheide, Scott A Busby, Tara L Muratore

Nat Protoc· June 2007

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HDM2-binding partners: interaction with translation elongation factor EF1alpha.
Rebecca Frum, Scott A Busby, Mahesh Ramamoorthy, Sumitra Deb, Jeffrey Shabanowitz

J Proteome Res· April 2007

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Genomic and functional evolution of the Drosophila melanogaster sperm proteome.
Steve Dorus, Scott A Busby, Ursula Gerike, Jeffrey Shabanowitz, Donald F Hunt

Nat Genet· December 2006

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Comprehensive phosphoprotein analysis of linker histone H1 from Tetrahymena thermophila.
Benjamin A Garcia, Swati Joshi, C Eric Thomas, Raghu K Chitta, Robert L Diaz, Scott A Busby

Mol Cell Proteomics· September 2006

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Structural mobility in human manganese superoxide dismutase.
Patrick Quint, Idelisa Ayala, Scott A Busby, Michael J Chalmers, Patrick R Griffin

Biochemistry· July 2006

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