Publications by authors named "Scott D Gleason"

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A medium throughput rodent model of relapse from addiction with behavioral and pharmacological specificity.
William J A Eiler, Scott D Gleason, Jodi L Smith, Jeffrey M Witkin

Pharmacol Biochem Behav· August 2019

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Targeted Blockade of TARP-γ8-Associated AMPA Receptors: Anticonvulsant Activity with the Selective Antagonist LY3130481 (CERC-611).
Jeffrey M Witkin, Douglas A Schober, Scott D Gleason, John T Catlow, Warren J Porter

CNS Neurol Disord Drug Targets· March 2019

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Evaluation of 5-HT receptor antagonism for the treatment of anxiety, depression, and schizophrenia through the use of receptor-deficient mice.
Olivia M Balcer, Matthew A Seager, Scott D Gleason, Xia Li, Kurt Rasmussen

Behav Brain Res· March 2019

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Effects of 5-HT receptor antagonists on behaviors of mice that detect drugs used in the treatment of anxiety, depression, or schizophrenia.
Julia Maxwell, Scott D Gleason, Julie Falcone, Kjell Svensson, Olivia M Balcer

Behav Brain Res· February 2019

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Pharmacological characterization of the neurotrophic sesquiterpene jiadifenolide reveals a non-convulsant signature and potential for progression in neurodegenerative disease studies.
Jeffrey M Witkin, Ryan A Shenvi, Xia Li, Scott D Gleason, Julie Weiss

Biochem Pharmacol· September 2018

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Chronic pain impairs cognitive flexibility and engages novel learning strategies in rats.
Stephen L Cowen, Caroline E Phelps, Edita Navratilova, David L McKinzie, Alec Okun, Scott D Gleason

Pain· July 2018

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Negative allosteric modulation of alpha 5-containing GABA receptors engenders antidepressant-like effects and selectively prevents age-associated hyperactivity in tau-depositing mice.
Nina Z Xu, Margot Ernst, Marco Treven, Rok Cerne, Mark Wakulchik, Scott D Gleason

Psychopharmacology (Berl)· April 2018

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Electroencephalographic, cognitive, and neurochemical effects of LY3130481 (CERC-611), a selective antagonist of TARP-γ8-associated AMPA receptors.
Jeffrey M Witkin, Jennifer Li, Gary Gilmour, Stephen N Mitchell, Guy Carter, Scott D Gleason

Neuropharmacology· November 2017

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Hedonic and motivational responses to food reward are unchanged in rats with neuropathic pain.
Alec Okun, David L McKinzie, Jeffrey M Witkin, Bethany Remeniuk, Omar Husein, Scott D Gleason

Pain· December 2016

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Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism.
Akihiko S Kato, Kevin D Burris, Kevin M Gardinier, Douglas L Gernert, Warren J Porter, Scott D Gleason

Nat Med· December 2016

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Preclinical findings predicting efficacy and side-effect profile of LY2940094, an antagonist of nociceptin receptors.
Jeffrey M Witkin, Linda M Rorick-Kehn, Mark J Benvenga, Benjamin L Adams, Scott D Gleason

Pharmacol Res Perspect· December 2016

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Discovery of the First α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antagonist Dependent upon Transmembrane AMPA Receptor Regulatory Protein (TARP) γ-8.
Kevin M Gardinier, Douglas L Gernert, Warren J Porter, Jon K Reel, Paul L Ornstein, Scott D Gleason

J Med Chem· May 2016

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Inquiries into the Biological Significance of Transmembrane AMPA Receptor Regulatory Protein (TARP) γ-8 Through Investigations of TARP γ-8 Null Mice§.
Scott D Gleason, Akihiko Kato, Hai H Bui, Linda K Thompson, Sabrina N Valli

CNS Neurol Disord Drug Targets· February 2016

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Further evaluation of the neuropharmacological determinants of the antidepressant-like effects of curcumin.
Jeffrey M Witkin, Susan Leucke, Linda K Thompson, Renee A Lynch, Chunjin Ding, Scott D Gleason

CNS Neurol Disord Drug Targets· June 2013

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Multiple dopamine receptors mediate the discriminative stimulus effects of dihydrexidine in rats.
Scott D Gleason, Tinggui Yin, Sheila P Little, Neil Delapp, Jeffrey M Witkin

Behav Pharmacol· September 2011

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A parametric analysis of punishment frequency as a determinant of the response to chlordiazepoxide in the Vogel conflict test in rats.
Scott D Gleason, Jeffrey M Witkin

Pharmacol Biochem Behav· October 2007

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Anxiolytic-like effects through a GLUK5 kainate receptor mechanism.
Andrew Alt, Brianne Weiss, Paul L Ornstein, Scott D Gleason, David Bleakman

Neuropharmacology· June 2007

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Effects of dopamine D1 receptor agonists in rats trained to discriminate dihydrexidine.
Scott D Gleason, Jeffrey M Witkin

Psychopharmacology (Berl)· May 2006

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In vitro and in vivo studies in rats with LY293558 suggest AMPA/kainate receptor blockade as a novel potential mechanism for the therapeutic treatment of anxiety disorders.
Andrew Alt, Brianne Weiss, Ann Marie Ogden, Xia Li, Scott D Gleason

Psychopharmacology (Berl)· April 2006

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