Publications by authors named "Scott Noggle"

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miR155 triplicated in Down syndrome regulates hippocampal GABAergic neurogenesis in Alzheimer's disease.
Xiaodong Zhu, Jean-Vianney Haure-Mirande, Mesude Bicak, Pengfei Dong, Ilya Kruglikov, Scott Noggle

bioRxiv· September 2025

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Establishing Neural Organoid Cultures for Investigating the Effects of Microgravity in Low-Earth Orbit (LEO).
Nicolette A Pirjanian, Kriti Kalpana, Ilya Kruglikov, Pinar Mesci, Jana Stoudemire, Scott A Noggle

Methods Mol Biol· July 2025

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Generating Neuroimmune Assembloids Using Human Induced Pluripotent Stem Cell (iPSC)-Derived Cortical Organoids and Microglia.
Kriti Kalpana, Chandrika Rao, Stefan Semrau, Bin Zhang, Scott Noggle

Methods Mol Biol· July 2025

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Genetics of growth rate in induced pluripotent stem cells.
Brian N Lee, Henry J Taylor, Filippo Cipriani, Narisu Narisu, Catherine C Robertson, Scott Noggle

bioRxiv· July 2025

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Author Correction: Modeling gene × environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expression.
Carina Seah, Michael S Breen, Tom Rusielewicz, Heather N Bader, Changxin Xu, Scott A Noggle

Nat Neurosci· January 2025

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Effects of microgravity on human iPSC-derived neural organoids on the International Space Station.
Davide Marotta, Laraib Ijaz, Lilianne Barbar, Madhura Nijsure, Jason Stein, Scott A Noggle

Stem Cells Transl Med· December 2024

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Common genetic variation impacts stress response in the brain.
Carina Seah, Rebecca Signer, Michael Deans, Heather Bader, Tom Rusielewicz, Scott A Noggle

bioRxiv· December 2023

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Isogenic human trophectoderm cells demonstrate the role of and associated variants in ZIKV infection.
Liuliu Yang, Yuling Han, Ting Zhou, Lauretta A Lacko, Mohsan Saeed, Scott A Noggle

iScience· July 2023

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Modeling gene × environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expression.
Carina Seah, Michael S Breen, Tom Rusielewicz, Heather N Bader, Changxin Xu, Scott A Noggle

Nat Neurosci· November 2022

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A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants.
Yuling Han, Lei Tan, Ting Zhou, Liuliu Yang, Lucia Carrau, Scott A Noggle

Cell Stem Cell· October 2022

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A dual knockin hESC reporter line for derivation of human SAN-like cells.
Zaniar Ghazizadeh, Jiajun Zhu, Faranak Fattahi, Alice Tang, Xiaolu Sun, Scott A Noggle

iScience· April 2022

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Integrating deep learning and unbiased automated high-content screening to identify complex disease signatures in human fibroblasts.
Lauren Schiff, Bianca Migliori, Ye Chen, Deidre Carter, Caitlyn Bonilla, Scott A Noggle

Nat Commun· March 2022

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Bioengineered models of Parkinson's disease using patient-derived dopaminergic neurons exhibit distinct biological profiles in a 3D microenvironment.
Nicholas J Fiore, Yosif M Ganat, Kapil Devkota, Rebecca Batorsky, Ming Lei, Scott A Noggle

Cell Mol Life Sci· January 2022

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Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors.
Valentina N Lagomarsino, Richard V Pearse, Lei Liu, Yi-Chen Hsieh, Marty A Fernandez, Scott Noggle

Neuron· November 2021

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Altered transcriptome and disease-related phenotype emerge only after fibroblasts harvested from patients with age-related macular degeneration are differentiated into retinal pigment epithelium.
Hui Cai, Jie Gong, , Scott Noggle, Daniel Paull

Exp Eye Res· June 2021

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Selective linkage of mitochondrial enzymes to intracellular calcium stores differs between human-induced pluripotent stem cells, neural stem cells, and neurons.
Huanlian Chen, Abigail C Cross, Ankita Thakkar, Hui Xu, Aiqun Li, Scott A Noggle

J Neurochem· March 2021

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Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer's Disease.
Minghui Wang, Aiqun Li, Michiko Sekiya, Noam D Beckmann, Xiuming Quan, Scott Noggle

Neuron· January 2021

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Molecular subtyping of Alzheimer's disease using RNA sequencing data reveals novel mechanisms and targets.
Ryan A Neff, Minghui Wang, Sezen Vatansever, Lei Guo, Chen Ming, Scott Noggle

Sci Adv· January 2021

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Stem cell-derived retinal pigment epithelium from patients with age-related macular degeneration exhibit reduced metabolism and matrix interactions.
Jie Gong, Hui Cai, , Scott Noggle, Daniel Paull

Stem Cells Transl Med· March 2020

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The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction.
Maria Carmen Inda, Suhasini Joshi, Tai Wang, Alexander Bolaender, Srinivasa Gandu, Scott A Noggle

Nat Commun· January 2020

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Autophagy Induction by Bexarotene Promotes Mitophagy in Presenilin 1 Familial Alzheimer's Disease iPSC-Derived Neural Stem Cells.
Patricia Martín-Maestro, Andrew Sproul, Hector Martinez, Dominik Paquet, Meri Gerges, Scott Noggle

Mol Neurobiol· December 2019

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Pre- and peri-implantation Zika virus infection impairs fetal development by targeting trophectoderm cells.
Lei Tan, Lauretta A Lacko, Ting Zhou, Delia Tomoiaga, Romulo Hurtado, Scott Noggle

Nat Commun· September 2019

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High-throughput screening identifies compounds that protect RPE cells from physiological stressors present in AMD.
Hui Cai, Jie Gong, Laura Abriola, Denton Hoyer, Nyscf Global Stem Cell Array Team, Scott Noggle

Exp Eye Res· August 2019

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Lipid Deprivation Induces a Stable, Naive-to-Primed Intermediate State of Pluripotency in Human PSCs.
Daniela Cornacchia, Chao Zhang, Bastian Zimmer, Sun Young Chung, Yujie Fan, Scott A Noggle

Cell Stem Cell· July 2019

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Quality control guidelines for clinical-grade human induced pluripotent stem cell lines.
Stephen Sullivan, Glyn N Stacey, Chihiro Akazawa, Naoki Aoyama, Ricardo Baptista, Scott Noggle

Regen Med· October 2018

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