Publications by authors named "Scott R Mckercher"

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Targeted protein S-nitrosylation of ACE2 inhibits SARS-CoV-2 infection.
Chang-Ki Oh, Tomohiro Nakamura, Nathan Beutler, Xu Zhang, Juan Piña-Crespo, Scott R McKercher

Nat Chem Biol· March 2023

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Targeted protein S-nitrosylation of ACE2 as potential treatment to prevent spread of SARS-CoV-2 infection.
Chang-Ki Oh, Tomohiro Nakamura, Nathan Beutler, Xu Zhang, Juan Piña-Crespo, Scott R McKercher

bioRxiv· April 2022

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TCA cycle metabolic compromise due to an aberrant S-nitrosoproteome in HIV-associated neurocognitive disorder with methamphetamine use.
Paschalis-Thomas Doulias, Tomohiro Nakamura, Henry Scott, Scott R McKercher, Abdullah Sultan

J Neurovirol· June 2021

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Correction to: TCA cycle metabolic compromise due to an aberrant S‑nitrosoproteome in HIV‑associated neurocognitive disorder with methamphetamine use.
Paschalis-Thomas Doulias, Tomohiro Nakamura, Henry Scott, Scott R McKercher, Abdullah Sultan

J Neurovirol· June 2021

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Novel Therapeutic Approach for Excitatory/Inhibitory Imbalance in Neurodevelopmental and Neurodegenerative Diseases.
Swagata Ghatak, Maria Talantova, Scott R McKercher, Stuart A Lipton

Annu Rev Pharmacol Toxicol· January 2021

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NitroSynapsin for the treatment of neurological manifestations of tuberous sclerosis complex in a rodent model.
Shu-Ichi Okamoto, Olga Prikhodko, Juan Pina-Crespo, Anthony Adame, Scott R McKercher

Neurobiol Dis· July 2019

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NitroSynapsin therapy for a mouse MEF2C haploinsufficiency model of human autism.
Shichun Tu, Mohd Waseem Akhtar, Rosa Maria Escorihuela, Alejandro Amador-Arjona, Vivek Swarup, Scott R McKercher

Nat Commun· November 2017

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Molecular Pathway to Protection From Age-Dependent Photoreceptor Degeneration in Mef2 Deficiency.
Saumya Nagar, Dorit Trudler, Scott R McKercher, Juan Piña-Crespo, Nobuki Nakanishi

Invest Ophthalmol Vis Sci· July 2017

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MEF2D haploinsufficiency downregulates the NRF2 pathway and renders photoreceptors susceptible to light-induced oxidative stress.
Saumya Nagar, Sarah M Noveral, Dorit Trudler, Kevin M Lopez, Scott R McKercher

Proc Natl Acad Sci U S A· May 2017

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Therapeutic advantage of pro-electrophilic drugs to activate the Nrf2/ARE pathway in Alzheimer's disease models.
Stuart A Lipton, Tayebeh Rezaie, Anthony Nutter, Kevin M Lopez, James Parker, Scott R McKercher

Cell Death Dis· December 2016

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Levetiracetam inhibits oligomeric Aβ-induced glutamate release from human astrocytes.
Sara Sanz-Blasco, Juan C Piña-Crespo, Xiaofei Zhang, Scott R McKercher, Stuart A Lipton

Neuroreport· June 2016

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Nrf2 and HSF-1 Pathway Activation via Hydroquinone-Based Proelectrophilic Small Molecules is Regulated by Electrochemical Oxidation Potential.
Takumi Satoh, Romain Stalder, Scott R McKercher, Robert E Williamson, Gregory P Roth

ASN Neuro· March 2016

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Corrigendum: Pharmacologically targeted NMDA receptor antagonism by NitroMemantine for cerebrovascular disease.
Hiroto Takahashi, Peng Xia, Jiankun Cui, Maria Talantova, Karthik Bodhinathan, Scott R McKercher

Sci Rep· February 2016

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Differential Effects of Pharmacologic and Genetic Modulation of NMDA Receptor Activity on HIV/gp120-Induced Neuronal Damage in an In Vivo Mouse Model.
Nobuki Nakanishi, Yeon-Joo Kang, Shichun Tu, Scott R McKercher, Eliezer Masliah

J Mol Neurosci· January 2016

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Elevated glucose and oligomeric β-amyloid disrupt synapses via a common pathway of aberrant protein S-nitrosylation.
Mohd Waseem Akhtar, Sara Sanz-Blasco, Nima Dolatabadi, James Parker, Kevin Chon, Scott R McKercher

Nat Commun· January 2016

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Aberrant protein S-nitrosylation contributes to the pathophysiology of neurodegenerative diseases.
Tomohiro Nakamura, Olga A Prikhodko, Elaine Pirie, Saumya Nagar, Mohd Waseem Akhtar, Scott R McKercher

Neurobiol Dis· December 2015

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Pharmacologically targeted NMDA receptor antagonism by NitroMemantine for cerebrovascular disease.
Hiroto Takahashi, Peng Xia, Jiankun Cui, Maria Talantova, Karthik Bodhinathan, Scott R McKercher

Sci Rep· October 2015

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Protection from cyanide-induced brain injury by the Nrf2 transcriptional activator carnosic acid.
Dongxian Zhang, Brian Lee, Anthony Nutter, Paul Song, Nima Dolatabadi, Scott R McKercher

J Neurochem· June 2015

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Transcriptional profiling of MEF2-regulated genes in human neural progenitor cells derived from embryonic stem cells.
Shing Fai Chan, Xiayu Huang, Scott R McKercher, Rameez Zaidi, Shu-Ichi Okamoto

Genom Data· March 2015

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Potential for cell therapy in Parkinson's disease using genetically programmed human embryonic stem cell-derived neural progenitor cells.
Rajesh Ambasudhan, Nima Dolatabadi, Anthony Nutter, Eliezer Masliah, Scott R Mckercher

J Comp Neurol· August 2014

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S-nitrosylation-mediated redox transcriptional switch modulates neurogenesis and neuronal cell death.
Shu-Ichi Okamoto, Tomohiro Nakamura, Piotr Cieplak, Shing Fai Chan, Evgenia Kalashnikova, Scott R McKercher

Cell Rep· July 2014

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Differential effects of synaptic and extrasynaptic NMDA receptors on Aβ-induced nitric oxide production in cerebrocortical neurons.
Elena Molokanova, Mohd Waseem Akhtar, Sara Sanz-Blasco, Shichun Tu, Juan C Piña-Crespo, Scott R McKercher

J Neurosci· April 2014

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ATM-dependent phosphorylation of MEF2D promotes neuronal survival after DNA damage.
Shing Fai Chan, Sam Sances, Laurence M Brill, Shu-Ichi Okamoto, Rameez Zaidi, Scott R McKercher

J Neurosci· March 2014

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Reprint of: Nrf2/ARE-mediated antioxidant actions of pro-electrophilic drugs.
Takumi Satoh, Scott R McKercher, Stuart A Lipton

Free Radic Biol Med· January 2014

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Small molecules enable OCT4-mediated direct reprogramming into expandable human neural stem cells.
Saiyong Zhu, Rajesh Ambasudhan, Woong Sun, Hyun Jung Kim, Maria Talantova, Scott R McKercher

Cell Res· January 2014

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