Publications by authors named "Sean B Lee"

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NEK Family Kinases: Structure, Function, and Role in Disease.
Brandon M Baker, Julia R Boehling, Sarah Knopf, Stephanie Held, Margarite Matossian, Sean B Lee

Biomolecules· October 2025

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EWS::WT1 Isoform-Dependent Regulation of Neogenes in Desmoplastic Small Round Cell Tumors.
Danh D Truong, Justin W Magrath, Kevin Murgas, Jiaqian Fan, Diana Shamsutdinova, Sean B Lee

bioRxiv· September 2025

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Editorial: New strategies for treating fusion-driven sarcomas.
Madelyn Espinosa-Cotton, Sean B Lee, Anand G Patel

Front Cell Dev Biol· April 2025

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A generative framework for enhanced cell-type specificity in rationally designed mRNAs.
Matvei Khoroshkin, Arsenii Zinkevich, Elizaveta Aristova, Hassan Yousefi, Sean B Lee

bioRxiv· December 2024

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Author Correction: Systematic identification of post-transcriptional regulatory modules.
Matvei Khoroshkin, Andrey Buyan, Martin Dodel, Albertas Navickas, Johnny Yu, Sean B Lee

Nat Commun· October 2024

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Systematic identification of post-transcriptional regulatory modules.
Matvei Khoroshkin, Andrey Buyan, Martin Dodel, Albertas Navickas, Johnny Yu, Sean B Lee

Nat Commun· September 2024

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Desmoplastic small round cell tumor: from genomics to targets, potential paths to future therapeutics.
Justin W Magrath, Madelyn Espinosa-Cotton, Dane A Flinchum, Shruthi Sanjitha Sampath, Nai Kong Cheung, Sean B Lee

Front Cell Dev Biol· July 2024

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Comprehensive Transcriptomic Analysis of EWSR1::WT1 Targets Identifies CDK4/6 Inhibitors as an Effective Therapy for Desmoplastic Small Round Cell Tumors.
Justin W Magrath, Shruthi Sanjitha Sampath, Dane A Flinchum, Alifiani B Hartono, Ilon N Goldberg, Sean B Lee

Cancer Res· May 2024

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Enzalutamide induces cytotoxicity in desmoplastic small round cell tumor independent of the androgen receptor.
Justin W Magrath, Ilon N Goldberg, Danh D Truong, Alifiani B Hartono, Shruthi Sanjitha Sampath, Sean B Lee

Commun Biol· April 2024

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Transcriptomic analysis identifies B-lymphocyte kinase as a therapeutic target for desmoplastic small round cell tumor cancer stem cell-like cells.
Justin W Magrath, Dane A Flinchum, Alifiani B Hartono, Shruthi Sanjitha Sampath, Tina M O'Grady, Sean B Lee

Oncogenesis· January 2024

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Enzalutamide Induces Cytotoxicity in Desmoplastic Small Round Cell Tumor Independent of the Androgen Receptor.
Justin W Magrath, Ilon N Goldberg, Danh D Truong, Alifiani B Hartono, Shruthi Sanjitha Sampath, Sean B Lee

bioRxiv· November 2023

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Genomic Breakpoint Characterization and Transcriptome Analysis of Metastatic, Recurrent Desmoplastic Small Round Cell Tumor.
Justin W Magrath, Dane A Flinchum, Alifiani B Hartono, Ilon N Goldberg, Madelyn Espinosa-Cotton, Sean B Lee

Sarcoma· July 2023

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LKB1 signaling and patient survival outcomes in hepatocellular carcinoma.
Khoa Nguyen, Katherine Hebert, Emily McConnell, Nicole Cullen, Thomas Cheng, Sean B Lee

Pharmacol Res· June 2023

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Editorial: Targeted therapies for aggressive cancers.
Sean B Lee, Geoffrey Brown

Front Cell Dev Biol· March 2023

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NEK Family Review and Correlations with Patient Survival Outcomes in Various Cancer Types.
Khoa Nguyen, Julia Boehling, Minh N Tran, Thomas Cheng, Andrew Rivera, Sean B Lee

Cancers (Basel)· March 2023

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Desmoplastic small round cell tumor cancer stem cell-like cells resist chemotherapy but remain dependent on the EWSR1-WT1 oncoprotein.
Justin W Magrath, Hong-Jun Kang, Alifiani Hartono, Madelyn Espinosa-Cotton, Romel Somwar, Sean B Lee

Front Cell Dev Biol· November 2022

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Expression of Novel Kinase MAP3K19 in Various Cancers and Survival Correlations.
Khoa Nguyen, Hassan Yousefi, Thomas Cheng, Justin Magrath, Alifiani B Hartono, Sean B Lee

Front Biosci (Landmark Ed)· June 2022

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MAP3K Family Review and Correlations with Patient Survival Outcomes in Various Cancer Types.
Khoa Nguyen, Minh N Tran, Andrew Rivera, Thomas Cheng, Gabrielle O Windsor, Sean B Lee

Front Biosci (Landmark Ed)· May 2022

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Salt-Inducible Kinase 1 is a potential therapeutic target in Desmoplastic Small Round Cell Tumor.
Alifiani Bonita Hartono, Hong-Jun Kang, Lawrence Shi, Whitney Phipps, Nathan Ungerleider, Lee Spraggon, Sean Bong Lee

Oncogenesis· April 2022

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Correction: Elevated ATGL in colon cancer cells and cancer stem cells promotes metabolic and tumorigenic reprogramming reinforced by obesity.
Rida Iftikhar, Harrison M Penrose, Angelle N King, Joshua S Samudre, Morgan E Collins, Sean B Lee

Oncogenesis· March 2022

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Novel patient-derived models of desmoplastic small round cell tumor confirm a targetable dependency on ERBB signaling.
Roger S Smith, Igor Odintsov, Zebing Liu, Allan Jo-Weng Lui, Takuo Hayashi, Sean B Lee, Lee Spraggon

Dis Model Mech· January 2022

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Elevated ATGL in colon cancer cells and cancer stem cells promotes metabolic and tumorigenic reprogramming reinforced by obesity.
Rida Iftikhar, Harrison M Penrose, Angelle N King, Joshua S Samudre, Morgan E Collins, Sean B Lee

Oncogenesis· November 2021

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Therapeutic Potential of NTRK3 Inhibition in Desmoplastic Small Round Cell Tumor.
Koichi Ogura, Romel Somwar, Julija Hmeljak, Heather Magnan, Ryma Benayed, Sean Bong Lee, Lee Spraggon

Clin Cancer Res· February 2021

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EWSR1, a multifunctional protein, regulates cellular function and aging via genetic and epigenetic pathways.
Junghee Lee, Phuong T Nguyen, Hyun Soo Shim, Seung Jae Hyeon, Hyeonjoo Im, Sean Bong Lee

Biochim Biophys Acta Mol Basis Dis· July 2019

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Loss of Forkhead Box O3 Facilitates Inflammatory Colon Cancer: Transcriptome Profiling of the Immune Landscape and Novel Targets.
Harrison M Penrose, Chloe Cable, Sandra Heller, Nathan Ungerleider, Hani Nakhoul, Sean B Lee

Cell Mol Gastroenterol Hepatol· May 2019

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