Publications by authors named "Sean Grimmond"

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Effects of CVA21, an Oncolytic Virus, in Combination with Pembrolizumab on Immunogenicity and the Tumor Microenvironment in Advanced NSCLC: A Phase I/II Trial.
Adithya Balasubramanian, Claire Marceaux, Sehrish Kanwal, Ilariya Tarasova, Daniel Batey, Sean Grimmond

Clin Cancer Res· November 2025

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Perioperative IDH inhibition in treatment-naive IDH-mutant glioma: a pilot trial.
Katharine J Drummond, Montana Spiteri, Sarah A Cain, Jordan Jones, Sammy Shaya, Sean Grimmond

Nat Med· October 2025

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Pathologist-initiated whole genome and transcriptome sequencing demonstrates diagnostic utility in resolving difficult-to-diagnose tumors.
Joseph H A Vissers, Catherine Mitchell, Owen W J Prall, Wing-Yee Lo, Sehrish Kanwal, Sean M Grimmond

Genome Med· October 2025

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Reply to: The chemotherapeutic drug CX-5461 is a potent mutagen in cultured human cells.
Sehrish Kanwal, Natalie Brajanovski, Jiajun Zhan, Joanna Chan, Richard Rebello, Sean Grimmond

medRxiv· October 2025

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Hepatitis B surface antigen is upregulated by HIV Tat in an HIV-hepatitis B virus co-infection model system.
Wei Zhao, Kasha Singh, Vitini Sozzi, Paula Cevaal, Fernando J Rossello, Sean Grimmond

Microbiol Spectr· September 2025

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Automated integration of multi-slice spatial transcriptomics data in 2D and 3D using VR-Omics.
Denis Bienroth, Natalie Charitakis, Dillon Wong, Yunhan C Zhang, Sabrina Jaeger-Honz, Sean Grimmond

Genome Biol· July 2025

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Neoadjuvant triplet immune checkpoint blockade in newly diagnosed glioblastoma.
Georgina V Long, Elena Shklovskaya, Laveniya Satgunaseelan, Yizhe Mao, Inês Pires da Silva, Sean M Grimmond

Nat Med· May 2025

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Whole genome sequencing improves tissue-of-origin diagnosis and treatment options for cancer of unknown primary.
Richard J Rebello, Atara Posner, Ruining Dong, Owen W J Prall, Tharani Sivakumaran, Sean M Grimmond

Nat Commun· May 2025

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Genomic mechanisms associated with resistance to PDL1-blockade in a patient with mantle cell lymphoma.
Samuel Grigg, Stephen Lade, Georgina Ryland, Sean Grimmond, Michael Dickinson

Leuk Lymphoma· April 2025

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Multi-omic analysis of SDHB-deficient pheochromocytomas and paragangliomas identifies metastasis and treatment-related molecular profiles.
Aidan Flynn, Andrew D Pattison, Shiva Balachander, Emma Boehm, Blake Bowen, Sean Grimmond

Nat Commun· March 2025

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CAR+ T-Cell Lymphoma after Cilta-cel Therapy for Relapsed or Refractory Myeloma.
Simon J Harrison, Cyrille Touzeau, Nicolas Kint, Katherine Li, Tamia Nguyen, Sean Grimmond

N Engl J Med· February 2025

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Unravelling mutational signatures with plasma circulating tumour DNA.
Sebastian Hollizeck, Ning Wang, Stephen Q Wong, Cassandra Litchfield, Jerick Guinto, Sean Grimmond

Nat Commun· November 2024

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Temporally resolved proteomics identifies nidogen-2 as a cotarget in pancreatic cancer that modulates fibrosis and therapy response.
Brooke A Pereira, Shona Ritchie, Cecilia R Chambers, Katie A Gordon, Astrid Magenau, Sean M Grimmond

Sci Adv· July 2024

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Multi-omic analysis of SDHB-deficient pheochromocytomas and paragangliomas identifies metastasis and treatment-related molecular profiles.
Aidan Flynn, Andrew D Pattison, Shiva Balachander, Emma Boehm, Blake Bowen, Sean Grimmond

Res Sq· June 2024

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Postoperative radiotherapy omission in selected patients with early breast cancer following preoperative breast MRI (PROSPECT): primary results of a prospective two-arm study.
Gregory Bruce Mann, Anita Rohini Skandarajah, Nicholas Zdenkowski, Janemary Hughes, Allan Park, Sean M Grimmond

Lancet· January 2024

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Clinical Impact of Comprehensive Molecular Profiling in Adolescents and Young Adults with Sarcoma.
Eden C Andrew, Jeremy Lewin, Jayesh Desai, Lisa Orme, Anne Hamilton, Sean M Grimmond

J Pers Med· January 2024

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A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer.
Jessica L Chitty, Michelle Yam, Lara Perryman, Amelia L Parker, Joanna N Skhinas, Sean M Grimmond

Nat Cancer· September 2023

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A Matched Molecular and Clinical Analysis of the Epithelioid Haemangioendothelioma Cohort in the Stafford Fox Rare Cancer Program and Contextual Literature Review.
Arwa Abdelmogod, Lia Papadopoulos, Stephen Riordan, Melvin Wong, Martin Weltman, Sean Grimmond

Cancers (Basel)· September 2023

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S100 family proteins are linked to organoid morphology and EMT in pancreatic cancer.
Ronnie Ren Jie Low, Ka Yee Fung, Hugh Gao, Adele Preaudet, Laura F Dagley, Sean M Grimmond

Cell Death Differ· May 2023

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Correction to: S100 family proteins are linked to organoid morphology and EMT in pancreatic cancer.
Ronnie Ren Jie Low, Ka Yee Fung, Hugh Gao, Adele Preaudet, Laura F Dagley, Sean M Grimmond

Cell Death Differ· May 2023

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Targeting homologous recombination deficiency in uterine leiomyosarcoma.
Genevieve Dall, Cassandra J Vandenberg, Ksenija Nesic, Gayanie Ratnayake, Wenying Zhu, Sean Grimmond

J Exp Clin Cancer Res· May 2023

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Australian Genomics: Outcomes of a 5-year national program to accelerate the integration of genomics in healthcare.
Zornitza Stark, Tiffany Boughtwood, Matilda Haas, Jeffrey Braithwaite, Clara L Gaff, Sean M Grimmond

Am J Hum Genet· March 2023

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Author Correction: Single-nuclei and bulk-tissue gene-expression analysis of pheochromocytoma and paraganglioma links disease subtypes with tumor microenvironment.
Magnus Zethoven, Luciano Martelotto, Andrew Pattison, Blake Bowen, Shiva Balachander, Sean Grimmond

Nat Commun· January 2023

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Implementation of Whole-Genome and Transcriptome Sequencing Into Clinical Cancer Care.
Edwin Cuppen, Olivier Elemento, Richard Rosenquist, Svetlana Nikic, Maarten IJzerman, Sean Grimmond

JCO Precis Oncol· December 2022

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qmotif: determination of telomere content from whole-genome sequence data.
Oliver Holmes, Katia Nones, Yue Hang Tang, Kelly A Loffler, Michael Lee, Sean M Grimmond

Bioinform Adv· January 2022

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