Publications by authors named "Sean Landrette"

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Preclinical Evaluation of Bavdegalutamide (ARV-110), a Novel PROteolysis TArgeting Chimera Androgen Receptor Degrader.
Lawrence B Snyder, Taavi K Neklesa, Ryan R Willard, Deborah A Gordon, Jennifer Pizzano, Sean Landrette

Mol Cancer Ther· April 2025

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Apilimod dimesylate in C9orf72 amyotrophic lateral sclerosis: a randomized phase 2a clinical trial.
Suma Babu, Katharine A Nicholson, Jeffrey D Rothstein, Andrea Swenson, Paul J Sampognaro, Sean Landrette

Brain· September 2024

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LAM-003, a new drug for treatment of tyrosine kinase inhibitor-resistant FLT3-ITD-positive AML.
Neil Beeharry, Sean Landrette, Sophia Gayle, Marylens Hernandez, Jeff E Grotzke

Blood Adv· November 2019

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Efficient genome-wide first-generation phenotypic screening system in mice using the transposon.
Hao Chang, Yukun Pan, Sean Landrette, Sheng Ding, Dong Yang

Proc Natl Acad Sci U S A· September 2019

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B-cell non-Hodgkin lymphoma: Selective vulnerability to PIKFYVE inhibition.
Sophia Gayle, Sean Landrette, Neil Beeharry, Chris Conrad, Marylens Hernandez

Autophagy· June 2017

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Identification of apilimod as a first-in-class PIKfyve kinase inhibitor for treatment of B-cell non-Hodgkin lymphoma.
Sophia Gayle, Sean Landrette, Neil Beeharry, Chris Conrad, Marylens Hernandez

Blood· March 2017

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piggyBac insertional mutagenesis screen identifies a role for nuclear RHOA in human ES cell differentiation.
Sophia Gayle, Yukun Pan, Sean Landrette, Tian Xu

Stem Cell Reports· May 2015

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Identification of PLX4032-resistance mechanisms and implications for novel RAF inhibitors.
Jaehyuk Choi, Sean F Landrette, Tiffany Wang, Perry Evans, Antonella Bacchiocchi

Pigment Cell Melanoma Res· March 2014

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Low-copy piggyBac transposon mutagenesis in mice identifies genes driving melanoma.
Thomas K Ni, Sean F Landrette, Robert D Bjornson, Marcus W Bosenberg, Tian Xu

Proc Natl Acad Sci U S A· September 2013

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Thrombopoietin/MPL participates in initiating and maintaining RUNX1-ETO acute myeloid leukemia via PI3K/AKT signaling.
John Anto Pulikkan, Dmitri Madera, Liting Xue, Paul Bradley, Sean Francis Landrette

Blood· July 2012

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Characterization of fluorescent eye markers for mammalian transgenic studies.
Jonathan C Cornett, Sean F Landrette, Tian Xu

PLoS One· May 2012

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piggyBac transposon somatic mutagenesis with an activated reporter and tracker (PB-SMART) for genetic screens in mice.
Sean F Landrette, Jonathan C Cornett, Thomas K Ni, Marcus W Bosenberg, Tian Xu

PLoS One· February 2012

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Somatic genetics empowers the mouse for modeling and interrogating developmental and disease processes.
Sean F Landrette, Tian Xu

PLoS Genet· July 2011

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Cbf beta-SMMHC induces distinct abnormal myeloid progenitors able to develop acute myeloid leukemia.
Ya-Huei Kuo, Sean F Landrette, Susan A Heilman, Paola N Perrat, Lisa Garrett

Cancer Cell· January 2006

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Plag1 and Plagl2 are oncogenes that induce acute myeloid leukemia in cooperation with Cbfb-MYH11.
Sean F Landrette, Ya-Huei Kuo, Karen Hensen, Sahar Barjesteh van Waalwijk van Doorn-Khosrovani, Paola N Perrat

Blood· April 2005

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