Publications by authors named "Sean Lyne"

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Shared metabolomic signatures for prognostic precision across brain injuries.
Santtu Hellström, Antti Sajanti, Aditya Jhaveri, Ying Cao, Fredrika Koskimäki, Seán B Lyne

Brain Spine· December 2025

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Soluble Urokinase-Type Plasminogen Activator Receptor and Inflammatory Biomarker Response with Prognostic Significance after Acute Neuronal Injury - a Prospective Cohort Study.
Antti Sajanti, Santtu Hellström, Carolyn Bennett, Abhinav Srinath, Aditya Jhaveri, Seán B Lyne

Inflammation· August 2025

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Common lipidomic signatures across distinct acute brain injuries in patient outcome prediction.
Santtu Hellström, Antti Sajanti, Abhinav Srinath, Carolyn Bennett, Romuald Girard, Seán B Lyne

Neurobiol Dis· January 2025

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Diagnostic and prognostic performance of urine ubiquitin carboxy-terminal hydrolase L1 across multiple acute brain injury types - A longitudinal prospective cohort study.
Santtu Hellström, Antti Sajanti, Aditya Jhaveri, Abhinav Srinath, Carolyn Bennett, Seán B Lyne

Brain Spine· December 2024

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Brain plasticity and neuroinflammatory protein biomarkers with circulating MicroRNAs as predictors of acute brain injury outcome - A prospective cohort study.
Antti Sajanti, Yan Li, Santtu Hellström, Ying Cao, Romuald Girard, Seán B Lyne

J Neurol Sci· September 2024

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A multi-institutional phase I study of acetazolamide with temozolomide in adults with newly diagnosed -methylated malignant glioma.
Riley K Driscoll, Sean B Lyne, David J Voce, Stefania Maraka, Vinai Gondi

Neurooncol Adv· February 2024

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Brain Plasticity Modulator p75 Neurotrophin Receptor in Human Urine after Different Acute Brain Injuries-A Prospective Cohort Study.
Santtu Hellström, Antti Sajanti, Abhinav Srinath, Carolyn Bennett, Romuald Girard, Seán B Lyne

Biomedicines· January 2024

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Outcome and survival of surgically treated acute subdural hematomas and postcraniotomy hematomas - A retrospective cohort study.
Iiro Heino, Antti Sajanti, Seán B Lyne, Janek Frantzén, Romuald Girard

Brain Spine· November 2023

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Towards a comprehensive understanding of p75 neurotrophin receptor functions and interactions in the brain.
Joel F Ritala, Seán B Lyne, Antti Sajanti, Romuald Girard, Janne Koskimäki

Neural Regen Res· April 2022

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Perfusion and permeability as diagnostic biomarkers of cavernous angioma with symptomatic hemorrhage.
Je Yeong Sone, Yan Li, Nicholas Hobson, Sharbel G Romanos, Abhinav Srinath, Seán B Lyne

J Cereb Blood Flow Metab· November 2021

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Intracerebral Hemorrhage Volume Reduction and Timing of Intervention Versus Functional Benefit and Survival in the MISTIE III and STICH Trials.
Sean P Polster, Julián Carrión-Penagos, Seán B Lyne, Barbara A Gregson, Ying Cao

Neurosurgery· April 2021

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An Alternative Pipeline for Glioblastoma Therapeutics: A Systematic Review of Drug Repurposing in Glioblastoma.
Seán B Lyne, Bakhtiar Yamini

Cancers (Basel)· April 2021

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Subclinical imaging changes in cerebral cavernous angiomas during prospective surveillance.
Julián Carrión-Penagos, Hussein A Zeineddine, Sean P Polster, Romuald Girard, Seán B Lyne

J Neurosurg· March 2021

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Thrombolysis for Evacuation of Intracerebral and Intraventricular Hemorrhage: A Guide to Surgical Protocols With Practical Lessons Learned From the MISTIE and CLEAR Trials.
Sean P Polster, Julián Carrión-Penagos, Seán B Lyne, Fernando D Goldenberg, Ali Mansour

Oper Neurosurg· December 2020

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Common transcriptome, plasma molecules, and imaging signatures in the aging brain and a Mendelian neurovascular disease, cerebral cavernous malformation.
Janne Koskimäki, Sean P Polster, Yan Li, Sharbel Romanos, Abhinav Srinath, Seán B Lyne

Geroscience· October 2020

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A comprehensive p75 neurotrophin receptor gene network and pathway analyses identifying new target genes.
Antti Sajanti, Seán B Lyne, Romuald Girard, Janek Frantzén, Tomi Rantamäki

Sci Rep· September 2020

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Editorial for "Ensemble Learning for Early-Response Prediction of Antidepressant Treatment in Major Depressive Disorder".
Abhinav Srinath, Sharbel Romanos, Seán B Lyne, Benjamin Leporq, Janne Koskimäki

J Magn Reson Imaging· July 2020

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Case Demonstrating the Nuances of Acute Cortical Venous Thrombosis Anticoagulation Guidelines.
Sean P Polster, Seán B Lyne, Ali Mansour

World Neurosurg· July 2020

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Dural Ectasia in Neurofibromatosis 1: Case Series, Management, and Review.
Sean P Polster, Mark C Dougherty, Hussein A Zeineddine, Seán B Lyne, Heather L Smith

Neurosurgery· May 2020

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Permissive microbiome characterizes human subjects with a neurovascular disease cavernous angioma.
Sean P Polster, Anukriti Sharma, Ceylan Tanes, Alan T Tang, Patricia Mericko, Seán B Lyne

Nat Commun· May 2020

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Symptomatic Brain Hemorrhages from Cavernous Angioma After Botulinum Toxin Injections, a Role of TLR/MEKK3 Mechanism? Case Report and Review of the Literature.
Janne Koskimäki, Dongdong Zhang, Julián Carrión-Penagos, Romuald Girard, Kristina Piedad, Seán Lyne

World Neurosurg· April 2020

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Transcriptome clarifies mechanisms of lesion genesis versus progression in models of Ccm3 cerebral cavernous malformations.
Janne Koskimäki, Dongdong Zhang, Yan Li, Laleh Saadat, Thomas Moore, Seán B Lyne

Acta Neuropathol Commun· August 2019

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Biomarkers of cavernous angioma with symptomatic hemorrhage.
Seán B Lyne, Romuald Girard, Janne Koskimäki, Hussein A Zeineddine, Dongdong Zhang

JCI Insight· June 2019

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Rho Kinase Inhibition Blunts Lesion Development and Hemorrhage in Murine Models of Aggressive Pdcd10/Ccm3 Disease.
Robert Shenkar, Amy Peiper, Heidy Pardo, Thomas Moore, Rhonda Lightle, Seán B Lyne

Stroke· March 2019

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Comprehensive transcriptome analysis of cerebral cavernous malformation across multiple species and genotypes.
Janne Koskimäki, Romuald Girard, Yan Li, Laleh Saadat, Hussein A Zeineddine, Seán Lyne

JCI Insight· February 2019

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