Publications by authors named "Sean M Sullivan"

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A phase I/II randomized, double-blinded, placebo-controlled trial of a self-amplifying Covid-19 mRNA vaccine.
Jenny G Low, Ruklanthi de Alwis, Shiwei Chen, Shirin Kalimuddin, Yan Shan Leong, Brian B Sullivan, Sean M Sullivan

NPJ Vaccines· December 2022

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A single dose of self-transcribing and replicating RNA-based SARS-CoV-2 vaccine produces protective adaptive immunity in mice.
Ruklanthi de Alwis, Esther S Gan, Shiwei Chen, Yan Shan Leong, Hwee Cheng Tan, Brian M Sullivan, Sean M Sullivan

Mol Ther· June 2021

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First-in-Human Phase 1 Study To Assess Safety, Tolerability, and Pharmacokinetics of a Novel Antifungal Drug, VL-2397, in Healthy Adults.
Mammen P Mammen, Danielle Armas, Frank H Hughes, Andrew M Hopkins, Cindy L Fisher, Sean M Sullivan

Antimicrob Agents Chemother· November 2019

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The Siderophore Transporter Sit1 Determines Susceptibility to the Antifungal VL-2397.
Anna-Maria Dietl, Matthias Misslinger, Mario M Aguiar, Vasyl Ivashov, David Teis, Sean M Sullivan

Antimicrob Agents Chemother· October 2019

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Population Pharmacokinetic Modeling of VL-2397, a Novel Systemic Antifungal Agent: Analysis of a Single- and Multiple-Ascending-Dose Study in Healthy Subjects.
Laura L Kovanda, Sean M Sullivan, Larry R Smith, Amit V Desai, Pete L Bonate

Antimicrob Agents Chemother· June 2019

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Vaccination with Vaxfectin(®) adjuvanted SIV DNA induces long-lasting humoral immune responses able to reduce SIVmac251 Viremia.
Viraj Kulkarni, Margherita Rosati, Antonio Valentin, Rashmi Jalah, Candido Alicea, Sean M Sullivan

Hum Vaccin Immunother· October 2013

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Vaxfectin adjuvant improves antibody responses of juvenile rhesus macaques to a DNA vaccine encoding the measles virus hemagglutinin and fusion proteins.
Wen-Hsuan W Lin, Adrian Vilalta, Robert J Adams, Alain Rolland, Sean M Sullivan

J Virol· June 2013

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Preclinical evaluation of Vaxfectin-adjuvanted Vero cell-derived seasonal split and pandemic whole virus influenza vaccines.
Larry R Smith, Walter Wodal, Brian A Crowe, Astrid Kerschbaum, Peter Bruehl, Sean M Sullivan

Hum Vaccin Immunother· June 2013

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A Vaxfectin(®)-adjuvanted HSV-2 plasmid DNA vaccine is effective for prophylactic and therapeutic use in the guinea pig model of genital herpes.
Ronald L Veselenak, Mark Shlapobersky, Richard B Pyles, Qun Wei, Sean M Sullivan

Vaccine· November 2012

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In vivo anti-tumor effect of expressing p14ARF-TAT using a FGF2-targeted cationic lipid vector.
Guoqin Niu, Wouter H P Driessen, Sean M Sullivan, Jeffrey A Hughes

Pharm Res· April 2011

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Vaxfectin: a versatile adjuvant for plasmid DNA- and protein-based vaccines.
Sean M Sullivan, John Doukas, Jukka Hartikka, Larry Smith, Alain Rolland

Expert Opin Drug Deliv· December 2010

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In vitro cytotoxic activity of cationic paclitaxel nanoparticles on MDR-3T3 cells.
Guoqin Niu, Carlos H Castro, Nam Nguyen, Sean M Sullivan, Jeffrey A Hughes

J Drug Target· July 2010

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Regulation of adult hematopoietic stem cells fate for enhanced tissue-specific repair.
Nilanjana Sengupta, Sergio Caballero, Sean M Sullivan, Lung-Ji Chang, Aqeela Afzal

Mol Ther· September 2009

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Development of peptide-targeted lipoplexes to CXCR4-expressing rat glioma cells and rat proliferating endothelial cells.
Wouter H P Driessen, Nobutaka Fujii, Hirokazu Tamamura, Sean M Sullivan

Mol Ther· March 2008

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IGF binding protein-3 regulates hematopoietic stem cell and endothelial precursor cell function during vascular development.
Kyung-Hee Chang, Tailoi Chan-Ling, Evan L McFarland, Aqeela Afzal, Hao Pan, Sean M Sullivan

Proc Natl Acad Sci U S A· June 2007

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Feasibility of weekly HIV drug delivery to enhance drug localization in lymphoid tissues based on pharmacokinetic models of lipid-associated indinavir.
Sonya J Snedecor, Sean M Sullivan, Rodney J Y Ho

Pharm Res· August 2006

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Formation of plasmid-based transfection complexes with an acid-labile cationic lipid: characterization of in vitro and in vivo gene transfer.
Jeremy A Boomer, David H Thompson, Sean M Sullivan

Pharm Res· September 2002

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