Publications by authors named "Larry R Smith"

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A randomised, placebo-controlled phase 3 study to evaluate the efficacy and safety of ASP0113, a DNA-based CMV vaccine, in seropositive allogeneic haematopoietic cell transplant recipients.
Per Ljungman, Arancha Bermudez, Aaron C Logan, Mohamed A Kharfan-Dabaja, Patrice Chevallier, Larry R Smith

EClinicalMedicine· March 2021

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Pharmacokinetics and Immunogenicity of ASP0113 in CMV-Seronegative Dialysis Patients and CMV-Seronegative and -Seropositive Healthy Subjects.
Peter L Bonate, Charles Van Sant, Kathy Cho, Erin C Zook, Larry R Smith

Clin Pharmacol Drug Dev· May 2020

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First-in-Human Phase 1 Study To Assess Safety, Tolerability, and Pharmacokinetics of a Novel Antifungal Drug, VL-2397, in Healthy Adults.
Mammen P Mammen, Danielle Armas, Frank H Hughes, Andrew M Hopkins, Cindy L Fisher, Larry R Smith

Antimicrob Agents Chemother· November 2019

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The Siderophore Transporter Sit1 Determines Susceptibility to the Antifungal VL-2397.
Anna-Maria Dietl, Matthias Misslinger, Mario M Aguiar, Vasyl Ivashov, David Teis, Larry R Smith

Antimicrob Agents Chemother· October 2019

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Population Pharmacokinetic Modeling of VL-2397, a Novel Systemic Antifungal Agent: Analysis of a Single- and Multiple-Ascending-Dose Study in Healthy Subjects.
Laura L Kovanda, Sean M Sullivan, Larry R Smith, Amit V Desai, Pete L Bonate

Antimicrob Agents Chemother· June 2019

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A cytomegalovirus DNA vaccine induces antibodies that block viral entry into fibroblasts and epithelial cells.
Michael A McVoy, Ronzo Lee, Frances M Saccoccio, Jukka Hartikka, Larry R Smith

Vaccine· December 2015

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Questionnaire for biotechs: Vical incorporated.
Igor P Bilinsky, Larry R Smith

Hum Vaccin Immunother· September 2015

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Clinical Development of a Cytomegalovirus DNA Vaccine: From Product Concept to Pivotal Phase 3 Trial.
Larry R Smith, Mary K Wloch, Jennifer A Chaplin, Michele Gerber, Alain P Rolland

Vaccines (Basel)· September 2013

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Preclinical evaluation of Vaxfectin-adjuvanted Vero cell-derived seasonal split and pandemic whole virus influenza vaccines.
Larry R Smith, Walter Wodal, Brian A Crowe, Astrid Kerschbaum, Peter Bruehl

Hum Vaccin Immunother· June 2013

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Reanalysis of TransVax immunogenicity.
Mohamed A Kharfan-Dabaja, Michael Boeckh, Marissa B Wilck, Amelia A Langston, Alice H Chu, Larry R Smith

Lancet Infect Dis· January 2013

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Preclinical evaluation of the immunogenicity and safety of plasmid DNA-based prophylactic vaccines for human cytomegalovirus.
Jukka Hartikka, Vesselina Bozoukova, Jane Morrow, Denis Rusalov, Mark Shlapobersky, Larry R Smith

Hum Vaccin Immunother· November 2012

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A novel therapeutic cytomegalovirus DNA vaccine in allogeneic haemopoietic stem-cell transplantation: a randomised, double-blind, placebo-controlled, phase 2 trial.
Mohamed A Kharfan-Dabaja, Michael Boeckh, Marissa B Wilck, Amelia A Langston, Alice H Chu, Larry R Smith

Lancet Infect Dis· April 2012

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Phase 1 clinical trials of the safety and immunogenicity of adjuvanted plasmid DNA vaccines encoding influenza A virus H5 hemagglutinin.
Larry R Smith, Mary K Wloch, Ming Ye, Luane R Reyes, Souphaphone Boutsaboualoy

Vaccine· March 2010

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Vaxfectin, a cationic lipid-based adjuvant for protein-based influenza vaccines.
Jukka Hartikka, Vesselina Bozoukova, Catherine K Yang, Ming Ye, Denis Rusalov, Larry R Smith

Vaccine· October 2009

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Evaluation of a plasmid DNA-based anthrax vaccine in rabbits, nonhuman primates and healthy adults.
Wendy A Keitel, John J Treanor, Hana M El Sahly, Thomas G Evans, Scott Kopper, Larry R Smith

Hum Vaccin· August 2009

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Modifying the HIV-1 env gp160 gene to improve pDNA vaccine-elicited cell-mediated immune responses.
Shakuntala Megati, Dorys Garcia-Hand, Sarah Cappello, Vidia Roopchand, Amjed Masood, Larry R Smith

Vaccine· September 2008

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Safety and immunogenicity of a bivalent cytomegalovirus DNA vaccine in healthy adult subjects.
Mary K Wloch, Larry R Smith, Souphaphone Boutsaboualoy, Luane Reyes, Christina Han, Heather D Smith

J Infect Dis· June 2008

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Plasmid DNA-based vaccines protect mice and ferrets against lethal challenge with A/Vietnam/1203/04 (H5N1) influenza virus.
Peggy A Lalor, Richard J Webby, Jane Morrow, Denis Rusalov, David C Kaslow, Larry R Smith

J Infect Dis· June 2008

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Vaxfectin-formulated influenza DNA vaccines encoding NP and M2 viral proteins protect mice against lethal viral challenge.
Gretchen S Jimenez, Rodrick Planchon, Qun Wei, Denis Rusalov, Andrew Geall, Larry R Smith

Hum Vaccin· February 2008

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Qualification and performance characteristics of a quantitative enzyme-linked immunosorbent assay for human lgG antibodies to anthrax lethal factor antigen.
Cheryl L Selinsky, Vanessa D Whitlow, Larry R Smith, David C Kaslow, Holly M Horton

Biologicals· April 2007

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Novel microneutralization assay for HCMV using automated data collection and analysis.
Anna Maria Abai, Larry R Smith, Mary K Wloch

J Immunol Methods· April 2007

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Cross-reactive neuraminidase antibodies afford partial protection against H5N1 in mice and are present in unexposed humans.
Matthew R Sandbulte, Gretchen S Jimenez, Adrianus C M Boon, Larry R Smith, John J Treanor

PLoS Med· February 2007

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Antitumor efficacy of Venezuelan equine encephalitis virus replicon particles encoding mutated HPV16 E6 and E7 genes.
M Cristina Cassetti, Sue P McElhiney, Vafa Shahabi, Jeffrey K Pullen, I Caroline Le Poole, Larry R Smith

Vaccine· January 2004

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Establishment of an HLA-A*0201 human papillomavirus type 16 tumor model to determine the efficacy of vaccination strategies in HLA-A*0201 transgenic mice.
Gretchen L Eiben, Markwin P Velders, Hans Schreiber, Maria Cristina Cassetti, Jeffrey K Pullen, Larry R Smith

Cancer Res· October 2002

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