Publications by authors named "Sean MacKay"

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Evidence for phospholipid self-organisation in concentrated ammonia-water environments.
Sean M Mackay, Ben Sutherland, Richard A Easingwood, Andrew Hopkins, Mihnea Bostina

Biochim Biophys Acta Biomembr· December 2024

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Single-Cell CD4 and CD8 T-Cell Secretome Profiling Reveals Temporal and Niche Differences in Acute Myeloid Leukemia Following Immune Checkpoint Blockade Therapy.
Jessica L Root, Poonam N Desai, Christopher Ly, Bofei Wang, Fatima Zahra Jelloul, Sean Mackay

Cancer Res Commun· March 2024

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A Phase I/II Trial of HER2 Vaccine-Primed Autologous T-Cell Infusions in Patients with Treatment Refractory HER2-Overexpressing Breast Cancer.
Mary L Disis, Yushe Dang, Andrew L Coveler, Jennifer S Childs, Doreen M Higgins, Sean Mackay

Clin Cancer Res· September 2023

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Camel nanobody-based B7-H3 CAR-T cells show high efficacy against large solid tumours.
Dan Li, Ruixue Wang, Tianyuzhou Liang, Hua Ren, Chaelee Park, Sean Mackay

Nat Commun· September 2023

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Applying single-cell highly multiplexed secretome proteomics to characterize immunotherapeutic products and predict clinical responses.
Weiming Ni, Edward X Han, Matthew Cyr, Sean Mackay, Jing Zhou

Proteomics· July 2023

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Laparoscopic Repair of Bochdalek Hernia: A Rare Presentation of Abdominal Pain in the Elderly.
Christopher Steen, Jia Hui Lee, Enoch Wong, Sean Mackay

Case Rep Surg· June 2023

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The IgG4 hinge with CD28 transmembrane domain improves VH-based CAR T cells targeting a membrane-distal epitope of GPC1 in pancreatic cancer.
Nan Li, Alex Quan, Dan Li, Jiajia Pan, Hua Ren, Sean Mackay

Nat Commun· April 2023

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Multiomics and spatial mapping characterizes human CD8 T cell states in cancer.
Stefan Naulaerts, Angeliki Datsi, Daniel M Borras, Asier Antoranz Martinez, Julie Messiaen, Sean Mackay

Sci Transl Med· April 2023

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Experiences of mothers and significant others in accessing comprehensive healthcare in the first 1000 days of life post-conception during COVID-19 in rural Uganda.
Mary-Grace Nakate, Sean Mackay, Eunice Ndirangu-Mugo, Valerie Fleming

BMC Pregnancy Childbirth· December 2022

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The Potential Role of Cytotoxic Immune Effectors in Induction, Progression and Pathogenesis of Amyotrophic Lateral Sclerosis (ALS).
Kawaljit Kaur, Po-Chun Chen, Meng-Wei Ko, Ao Mei, Nishant Chovatiya, Sean Mackay

Cells· October 2022

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An On-Demand Drug Delivery System for Control of Epileptiform Seizures.
Takashi Nakano, Shakila B Rizwan, David M A Myint, Jason Gray, Sean M Mackay

Pharmaceutics· February 2022

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Single-cell polyfunctional proteomics of CD4 cells from patients with AML predicts responses to anti-PD-1-based therapy.
Hussein A Abbas, Zoe Alaniz, Sean Mackay, Matthew Cyr, Jing Zhou

Blood Adv· November 2021

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CAR T cells with dual targeting of CD19 and CD22 in adult patients with recurrent or refractory B cell malignancies: a phase 1 trial.
Jay Y Spiegel, Shabnum Patel, Lori Muffly, Nasheed M Hossain, Jean Oak, Sean Mackay

Nat Med· August 2021

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Tumor-derived NKG2D ligand sMIC reprograms NK cells to an inflammatory phenotype through CBM signalosome activation.
Payal Dhar, Fahmin Basher, Zhe Ji, Lei Huang, Si Qin, Sean MacKay

Commun Biol· July 2021

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Complement-activated human endothelial cells stimulate increased polyfunctionality in alloreactive T cells.
Catherine B Xie, Jing Zhou, Sean Mackay, Jordan S Pober

Am J Transplant· May 2021

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Targeted Co-delivery of Tumor Antigen and α-Galactosylceramide to CD141 Dendritic Cells Induces a Potent Tumor Antigen-Specific Human CD8 T Cell Response in Human Immune System Mice.
Jing Huang, Jing Zhou, Reem Ghinnagow, Toshiyuki Seki, Sho Iketani, Sean MacKay

Front Immunol· April 2021

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Longitudinal profiling of respiratory and systemic immune responses reveals myeloid cell-driven lung inflammation in severe COVID-19.
Peter A Szabo, Pranay Dogra, Joshua I Gray, Steven B Wells, Thomas J Connors, Sean Mackay

Immunity· April 2021

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Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19.
Yapeng Su, Daniel Chen, Dan Yuan, Christopher Lausted, Jongchan Choi, Sean Mackay

Cell· December 2020

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Changes in Peripheral and Local Tumor Immunity after Neoadjuvant Chemotherapy Reshape Clinical Outcomes in Patients with Breast Cancer.
Margaret L Axelrod, Mellissa J Nixon, Paula I Gonzalez-Ericsson, Riley E Bergman, Mark A Pilkinton, Sean Mackay

Clin Cancer Res· November 2020

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Analysis of respiratory and systemic immune responses in COVID-19 reveals mechanisms of disease pathogenesis.
Peter A Szabo, Pranay Dogra, Joshua I Gray, Steven B Wells, Thomas J Connors, Sean Mackay

medRxiv· October 2020

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Multiomic Immunophenotyping of COVID-19 Patients Reveals Early Infection Trajectories.
Yapeng Su, Daniel Chen, Christopher Lausted, Dan Yuan, Jongchan Choi, Sean Mackay

bioRxiv· July 2020

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Developing a new generation of scientist communicators through effective public outreach.
Sean M Mackay, Eng Wui Tan, David S Warren

Commun Chem· June 2020

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Acute encephalopathy with elevated CSF inflammatory markers as the initial presentation of COVID-19.
Shelli Farhadian, Laura R Glick, Chantal B F Vogels, Jared Thomas, Jennifer Chiarella, Sean MacKay

BMC Neurol· June 2020

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Acute encephalopathy with elevated CSF inflammatory markers as the initial presentation of COVID-19.
Shelli Farhadian, Laura R Glick, Chantal B F Vogels, Jared Thomas, Jennifer Chiarella, Sean MacKay

Res Sq· May 2020

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