Publications by authors named "Sean Zhu"

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Development of rat and mouse models of heme-iron absorption.
Jennifer K Lee, Yue He, Shireen Rl Flores, Regina R Woloshun, Xiaoyu Wang, Sean Zhu

JCI Insight· June 2025

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Human absorption, distribution, metabolism, and excretion studies: Conventional or microtracer?
Sean Xiaochun Zhu

Drug Metab Dispos· May 2025

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In vivo silencing of intestinal DMT1 mitigates iron loading in β-thalassemia intermedia (Hbbth3/+) mice.
Yang Yu, Regina R Woloshun, Jennifer K Lee, Pearl O Ebea-Ugwuanyi, Jacob S Shine, Sean Zhu

Blood Adv· November 2024

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The Current State of Biotransformation Science - Industry Survey of In Vitro and In Vivo Practices, Clinical Translation, and Future Trends.
John P Savaryn, Kevin Coe, Matthew A Cerny, Kevin Colizza, Patricia Moliner, Sean Xiaochun Zhu

Pharm Res· November 2024

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Metabolism and Excretion of [C]Mobocertinib, a Selective Covalent Inhibitor of Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion Mutations, in Healthy Male Subjects.
Hao Chen, Abhi Shah, Suguru Kato, Robert Griffin, Steven Zhang, Sean Xiaochun Zhu

Drug Metab Dispos· September 2024

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A phase 1 study to assess the absolute bioavailability, mass balance, pharmacokinetics, metabolism, and excretion of [C]-mobocertinib, an oral inhibitor of EGFR exon 20 insertion mutations, in healthy participants.
Michael J Hanley, Steven Zhang, Robert Griffin, Sean Xiaochun Zhu, Robert J Fram

Invest New Drugs· August 2024

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Investigation of the absolute bioavailability, mass balance, metabolism, and excretion of the cholesterol 24-hydroxylase inhibitor soticlestat in healthy volunteers.
Wei Yin, T Eric Ballard, Sean Xiaochun Zhu, Samuel Hsiao, Hao Chen

Br J Clin Pharmacol· February 2024

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Metabolism and Excretion of Therapeutic Peptides: Current Industry Practices, Perspectives, and Recommendations.
Minxia Michelle He, Sean Xiaochun Zhu, Joe R Cannon, Jesper Kammersgaard Christensen, Ruchia Duggal

Drug Metab Dispos· November 2023

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Fetal factors disrupt placental and maternal iron homeostasis in murine β-thalassemia.
Yang Yu, Regina R Woloshun, Jennifer K Lee, Pearl Onuwa Ebea, Sean Zhu

Blood· July 2023

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Four AAs increase DMT1 abundance in duodenal brush-border membrane vesicles and enhance iron absorption in iron-deprived mice.
Regina R Woloshun, Yang Yu, Xiaodong Xu, Jennifer K Lee, Sean Zhu

Blood Adv· May 2022

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Prospective Cohort of Deep Dyspareunia in an Interdisciplinary Setting.
Paul J Yong, Christina Williams, Sonja Bodmer-Roy, Chukwuemeka Ezeigwe, Sean Zhu

J Sex Med· December 2018

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Chronic pelvic pain in an interdisciplinary setting: 1-year prospective cohort.
Catherine Allaire, Christina Williams, Sonja Bodmer-Roy, Sean Zhu, Kristina Arion

Am J Obstet Gynecol· January 2018

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