Publications by authors named "Sebastiaan Meijsing"

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High-throughput screening of glucocorticoid-induced enhancer activity reveals mechanisms of stress-related psychiatric disorders.
Signe Penner-Goeke, Melissa Bothe, Nils Rek, Peter Kreitmaier, Dorothee Pöhlchen, Sebastiaan Meijsing

Proc Natl Acad Sci U S A· December 2023

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Assessing genome-wide dynamic changes in enhancer activity during early mESC differentiation by FAIRE-STARR-seq.
Laura V Glaser, Mara Steiger, Alisa Fuchs, Alena van Bömmel, Edda Einfeldt, Sebastiaan H Meijsing

Nucleic Acids Res· December 2021

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Glucocorticoid signaling induces transcriptional memory and universally reversible chromatin changes.
Melissa Bothe, René Buschow, Sebastiaan H Meijsing

Life Sci Alliance· October 2021

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Androgen and glucocorticoid receptor direct distinct transcriptional programs by receptor-specific and shared DNA binding sites.
Marina Kulik, Melissa Bothe, Gözde Kibar, Alisa Fuchs, Stefanie Schöne, Sebastiaan H Meijsing

Nucleic Acids Res· April 2021

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Glucocorticoid resistance of allogeneic T cells alters the gene expression profile in the inflamed small intestine of mice suffering from acute graft-versus-host disease.
Hu Li, Tina K Kaiser, Marina Borschiwer, Hanibal Bohnenberger, Sybille D Reichardt, Sebastiaan H Meijsing

J Steroid Biochem Mol Biol· December 2019

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CRUP: a comprehensive framework to predict condition-specific regulatory units.
Anna Ramisch, Verena Heinrich, Laura V Glaser, Alisa Fuchs, Xinyi Yang, Sebastiaan H Meijsing

Genome Biol· November 2019

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Pluripotency reprogramming by competent and incompetent POU factors uncovers temporal dependency for Oct4 and Sox2.
Vikas Malik, Laura V Glaser, Dennis Zimmer, Sergiy Velychko, Mingxi Weng, Sebastiaan H Meijsing

Nat Commun· August 2019

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Expanding the repertoire of glucocorticoid receptor target genes by engineering genomic response elements.
Verena Thormann, Laura V Glaser, Maika C Rothkegel, Marina Borschiwer, Melissa Bothe, Sebastiaan H Meijsing

Life Sci Alliance· April 2019

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Synthetic STARR-seq reveals how DNA shape and sequence modulate transcriptional output and noise.
Stefanie Schöne, Melissa Bothe, Edda Einfeldt, Marina Borschiwer, Philipp Benner, Sebastiaan H Meijsing

PLoS Genet· November 2018

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Loss of the Hematopoietic Stem Cell Factor GATA2 in the Osteogenic Lineage Impairs Trabecularization and Mechanical Strength of Bone.
Alexander Tolkachov, Cornelius Fischer, Thomas H Ambrosi, Melissa Bothe, Chung-Ting Han, Sebastiaan H Meijsing

Mol Cell Biol· June 2018

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Genomic dissection of enhancers uncovers principles of combinatorial regulation and cell type-specific wiring of enhancer-promoter contacts.
Verena Thormann, Maika C Rothkegel, Robert Schöpflin, Laura V Glaser, Petar Djuric, Sebastiaan H Meijsing

Nucleic Acids Res· April 2018

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Genomic dissection of enhancers uncovers principles of combinatorial regulation and cell type-specific wiring of enhancer-promoter contacts.
Verena Thormann, Maika C Rothkegel, Robert Schöpflin, Laura V Glaser, Petar Djuric, Sebastiaan H Meijsing

Nucleic Acids Res· April 2018

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Identification and characterization of BATF3 as a context-specific coactivator of the glucocorticoid receptor.
Petra Birth, Stefanie Schöne, Ulrich Stelzl, Sebastiaan H Meijsing

PLoS One· September 2017

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Airway Epithelial Cells Are Crucial Targets of Glucocorticoids in a Mouse Model of Allergic Asthma.
Carina Klaßen, Anna Karabinskaya, Lien Dejager, Sabine Vettorazzi, Justine Van Moorleghem, Sebastiaan H Meijsing

J Immunol· July 2017

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Role of the chromatin landscape and sequence in determining cell type-specific genomic glucocorticoid receptor binding and gene regulation.
Michael I Love, Matthew R Huska, Marcel Jurk, Robert Schöpflin, Stephan R Starick, Sebastiaan H Meijsing

Nucleic Acids Res· February 2017

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Corrigendum: Sequences flanking the core-binding site modulate glucocorticoid receptor structure and activity.
Stefanie Schöne, Marcel Jurk, Mahdi Bagherpoor Helabad, Iris Dror, Isabelle Lebars, Sebastiaan H Meijsing

Nat Commun· November 2016

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Sequences flanking the core-binding site modulate glucocorticoid receptor structure and activity.
Stefanie Schöne, Marcel Jurk, Mahdi Bagherpoor Helabad, Iris Dror, Isabelle Lebars, Sebastiaan H Meijsing

Nat Commun· September 2016

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The caffeine-binding adenosine A2A receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function.
Vânia L Batalha, Diana G Ferreira, Joana E Coelho, Jorge S Valadas, Rui Gomes, Sebastiaan H Meijsing

Sci Rep· August 2016

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Identification and characterization of DNA sequences that prevent glucocorticoid receptor binding to nearby response elements.
Jonas Telorac, Sergey V Prykhozhij, Stefanie Schöne, David Meierhofer, Sascha Sauer, Sebastiaan H Meijsing

Nucleic Acids Res· July 2016

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Mechanisms of Glucocorticoid-Regulated Gene Transcription.
Sebastiaan H Meijsing

Adv Exp Med Biol· October 2015

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ChIP-exo signal associated with DNA-binding motifs provides insight into the genomic binding of the glucocorticoid receptor and cooperating transcription factors.
Stephan R Starick, Jonas Ibn-Salem, Marcel Jurk, Céline Hernandez, Michael I Love, Sebastiaan H Meijsing

Genome Res· June 2015

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A naturally occurring insertion of a single amino acid rewires transcriptional regulation by glucocorticoid receptor isoforms.
Morgane Thomas-Chollier, Lisa C Watson, Samantha B Cooper, Miles A Pufall, Jennifer S Liu, Sebastiaan H Meijsing

Proc Natl Acad Sci U S A· October 2013

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Zebrafish Expression Ontology of Gene Sets (ZEOGS): a tool to analyze enrichment of zebrafish anatomical terms in large gene sets.
Sergey V Prykhozhij, Annalisa Marsico, Sebastiaan H Meijsing

Zebrafish· September 2013

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Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome.
Russell C DeKelver, Vivian M Choi, Erica A Moehle, David E Paschon, Dirk Hockemeyer, Sebastiaan H Meijsing

Genome Res· August 2010

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DNA binding site sequence directs glucocorticoid receptor structure and activity.
Sebastiaan H Meijsing, Miles A Pufall, Alex Y So, Darren L Bates, Lin Chen

Science· April 2009

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