Publications by authors named "Sebastien Goudreau"

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A General Synthesis Approach to Double-Guanidinium Stapled Peptides and Foldamers.
Maxime Neuville, Marta Martin Bornez, Mathieu Bourgeais, Hugues Samueli, Laura Mauran, Sébastien R Goudreau

Chemistry· November 2025

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Optimal Stapling of a Helical Peptide-Foldamer Hybrid Using a C-Terminal 4-Mercaptoproline Enhances Protein Surface Recognition and Cellular Activity.
Maxime Neuville, Mathieu Bourgeais, Jérémie Buratto, Claire Saragaglia, Bo Li, Sébastien R Goudreau

Chemistry· April 2025

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Cell-Permeable Peptide Inhibitors of the p53-hDM2 Interaction via Foldamer Helix Mimicry and Bis-Thioether Stapling.
Maxime Neuville, Mathieu Bourgeais, Bo Li, Laetitia Varajao, François Hallé, Sébastien R Goudreau

J Med Chem· January 2025

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Short Oligourea Foldamers as N- or C-Caps for Promoting α-Helix Formation in Water.
Laura Mauran, Coralie Assailly, Sébastien R Goudreau, Benoît Odaert, Gilles Guichard

Chembiochem· October 2024

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Structural Basis for α-Helix Mimicry and Inhibition of Protein-Protein Interactions with Oligourea Foldamers.
Léonie Cussol, Laura Mauran-Ambrosino, Jérémie Buratto, Anna Y Belorusova, Maxime Neuville, Sébastien R Goudreau

Angew Chem Int Ed Engl· February 2021

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Ureidopeptide GLP-1 analogues with prolonged activity signal bias and altered receptor trafficking.
Juliette Fremaux, Claire Venin, Laura Mauran, Robert Zimmer, Florian Koensgen, Sébastien R Goudreau

Chem Sci· November 2019

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Peptide-oligourea hybrids analogue of GLP-1 with improved action in vivo.
Juliette Fremaux, Claire Venin, Laura Mauran, Robert H Zimmer, Gilles Guichard, Sébastien R Goudreau

Nat Commun· February 2019

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Improved zinc-catalyzed Simmons-Smith reaction: access to various 1,2,3-trisubstituted cyclopropanes.
Éric Lévesque, Sébastien R Goudreau, André B Charette

Org Lett· March 2014

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Metal-free coupling of azoles with 2- and 3-haloindoles providing access to novel 2- or 3-(azol-1-yl)indole derivatives.
Martin Poirier, Sébastien Goudreau, Jason Poulin, Jolaine Savoie, Pierre L Beaulieu

Org Lett· May 2010

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Defying ring strain: new approaches to cyclopropanes.
Sébastien R Goudreau, André B Charette

Angew Chem Int Ed Engl· March 2010

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Synthesis of enantioenriched allenes from 1,1-cyclopropanediesters.
Pascal Cérat, Philipp J Gritsch, Sébastien R Goudreau, André B Charette

Org Lett· February 2010

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trans-Directing ability of the amide group: enabling the enantiocontrol in the synthesis of 1,1-dicarboxy cyclopropanes. Reaction development, scope, and synthetic applications.
David Marcoux, Sébastien R Goudreau, André B Charette

J Org Chem· December 2009

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In situ generation of zinc carbenoids from diazo compounds and zinc salts: asymmetric synthesis of 1,2,3-substituted cyclopropanes.
Sébastien R Goudreau, André B Charette

J Am Chem Soc· November 2009

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General method for the synthesis of phenyliodonium ylides from malonate esters: easy access to 1,1-cyclopropane diesters.
Sébastien R Goudreau, David Marcoux, André B Charette

J Org Chem· January 2009

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Cycloadditions of aromatic azomethine imines with 1,1-cyclopropane diesters.
Christian Perreault, Sébastien R Goudreau, Lucie E Zimmer, André B Charette

Org Lett· March 2008

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