Publications by authors named "Sergio Visentin"

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Astrocytes differentiated from patient iPSCs model the rare leukodystrophy MLC and uncover disease-linked maturation defects and Kir4.1 channel dysfunction.
Angela Lanciotti, Maria Stefania Brignone, Chiara De Nuccio, Sara Sposito, Elena Sofia Caprini, Sergio Visentin

Neurobiol Dis· January 2026

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Glial Ion Channels in Myelin Pathophysiology: Insights from Leukodystrophies.
Marcello Belfiore, Sergio Visentin, Elena Ambrosini

Life (Basel)· December 2025

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Demyelinating Diseases: From Molecular Mechanisms to Therapeutic Strategies.
Antonietta Bernardo, Sergio Visentin

Int J Mol Sci· February 2023

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The CaMKII/MLC1 Axis Confers Ca-Dependence to Volume-Regulated Anion Channels (VRAC) in Astrocytes.
Maria Stefania Brignone, Angela Lanciotti, Antonio Michelucci, Cinzia Mallozzi, Serena Camerini, Sergio Visentin

Cells· August 2022

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Repurposing Dipyridamole in Niemann Pick Type C Disease: A Proof of Concept Study.
Rita Pepponi, Roberta De Simone, Chiara De Nuccio, Sergio Visentin, Andrea Matteucci

Int J Mol Sci· March 2022

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Human iPSC-Derived Astrocytes: A Powerful Tool to Study Primary Astrocyte Dysfunction in the Pathogenesis of Rare Leukodystrophies.
Angela Lanciotti, Maria Stefania Brignone, Pompeo Macioce, Sergio Visentin, Elena Ambrosini

Int J Mol Sci· December 2021

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Myelin Defects in Niemann-Pick Type C Disease: Mechanisms and Possible Therapeutic Perspectives.
Antonietta Bernardo, Chiara De Nuccio, Sergio Visentin, Alberto Martire, Luisa Minghetti

Int J Mol Sci· August 2021

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The Antihypertensive Drug Telmisartan Protects Oligodendrocytes from Cholesterol Accumulation and Promotes Differentiation by a PPAR-γ-Mediated Mechanism.
Antonietta Bernardo, Mariagiovanna Malara, Lucia Bertuccini, Chiara De Nuccio, Sergio Visentin

Int J Mol Sci· August 2021

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DRP1 Inhibition Rescues Mitochondrial Integrity and Excessive Apoptosis in CS-A Disease Cell Models.
Barbara Pascucci, Francesca Spadaro, Donatella Pietraforte, Chiara De Nuccio, Sergio Visentin

Int J Mol Sci· July 2021

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Curcumin promotes oligodendrocyte differentiation and their protection against TNF-α through the activation of the nuclear receptor PPAR-γ.
Antonietta Bernardo, Cristina Plumitallo, Chiara De Nuccio, Sergio Visentin, Luisa Minghetti

Sci Rep· March 2021

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NRF2 and PPAR-γ Pathways in Oligodendrocyte Progenitors: Focus on ROS Protection, Mitochondrial Biogenesis and Promotion of Cell Differentiation.
Chiara De Nuccio, Antonietta Bernardo, Carmen Troiano, Maria Stefania Brignone, Mario Falchi, Sergio Visentin

Int J Mol Sci· September 2020

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Megalencephalic Leukoencephalopathy with Subcortical Cysts Disease-Linked MLC1 Protein Favors Gap-Junction Intercellular Communication by Regulating Connexin 43 Trafficking in Astrocytes.
Angela Lanciotti, Maria Stefania Brignone, Marcello Belfiore, Sandra Columba-Cabezas, Cinzia Mallozzi, Sergio Visentin

Cells· June 2020

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The activity of the Striatal-enriched protein tyrosine phosphatase in neuronal cells is modulated by adenosine A receptor.
Cinzia Mallozzi, Rita Pepponi, Sergio Visentin, Valentina Chiodi, Paul J Lombroso

J Neurochem· February 2020

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Adenosine A receptor stimulation restores cell functions and differentiation in Niemann-Pick type C-like oligodendrocytes.
Chiara De Nuccio, Antonietta Bernardo, Antonella Ferrante, Rita Pepponi, Alberto Martire, Sergio Visentin

Sci Rep· July 2019

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Overexpression of parkin rescues the defective mitochondrial phenotype and the increased apoptosis of Cockayne Syndrome A cells.
Barbara Pascucci, Mariarosaria D'Errico, Alessandra Romagnoli, Chiara De Nuccio, Miriam Savino, Sergio Visentin

Oncotarget· November 2017

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A Calsequestrin-1 Mutation Associated with a Skeletal Muscle Disease Alters Sarcoplasmic Ca2+ Release.
Maria Cristina D'Adamo, Luigi Sforna, Sergio Visentin, Alessandro Grottesi, Llenio Servettini

PLoS One· July 2017

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Megalencephalic leukoencephalopathy with subcortical cysts protein-1 regulates epidermal growth factor receptor signaling in astrocytes.
Angela Lanciotti, Maria Stefania Brignone, Sergio Visentin, Chiara De Nuccio, Luigi Catacuzzeno

Hum Mol Genet· April 2016

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An altered redox balance and increased genetic instability characterize primary fibroblasts derived from xeroderma pigmentosum group A patients.
Eleonora Parlanti, Donatella Pietraforte, Egidio Iorio, Sergio Visentin, Chiara De Nuccio

Mutat Res· December 2015

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The mitochondrial uncoupling protein-2 is a master regulator of both M1 and M2 microglial responses.
Roberta De Simone, Maria Antonietta Ajmone-Cat, Manuela Pandolfi, Antonietta Bernardo, Chiara De Nuccio, Sergio Visentin

J Neurochem· October 2015

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MLC1 protein: a likely link between leukodystrophies and brain channelopathies.
Maria S Brignone, Angela Lanciotti, Serena Camerini, Chiara De Nuccio, Tamara C Petrucci, Sergio Visentin

Front Cell Neurosci· April 2015

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Nonenzymatic oxygenated metabolites of α-linolenic acid B1- and L1-phytoprostanes protect immature neurons from oxidant injury and promote differentiation of oligodendrocyte progenitors through PPAR-γ activation.
Luisa Minghetti, Rachele Salvi, Maria Lavinia Salvatori, Maria Antonietta Ajmone-Cat, Chiara De Nuccio, Sergio Visentin

Free Radic Biol Med· August 2014

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Megalencephalic leukoencephalopathy with subcortical cysts protein-1 modulates endosomal pH and protein trafficking in astrocytes: relevance to MLC disease pathogenesis.
Maria S Brignone, Angela Lanciotti, Sergio Visentin, Chiara De Nuccio, Paola Molinari

Neurobiol Dis· June 2014

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Thapsigargin affects presenilin-2 but not presenilin-1 regulation in SK-N-BE cells.
Roberto Rivabene, Sergio Visentin, Paola Piscopo, Chiara De Nuccio, Alessio Crestini

Exp Biol Med (Maywood)· February 2014

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The nuclear receptor peroxisome proliferator-activated receptor-γ promotes oligodendrocyte differentiation through mechanisms involving mitochondria and oscillatory Ca2+ waves.
Antonietta Bernardo, Roberta De Simone, Chiara De Nuccio, Sergio Visentin, Luisa Minghetti

Biol Chem· December 2013

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The stimulation of adenosine A2A receptors ameliorates the pathological phenotype of fibroblasts from Niemann-Pick type C patients.
Sergio Visentin, Chiara De Nuccio, Antonietta Bernardo, Rita Pepponi, Antonella Ferrante

J Neurosci· September 2013

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