Publications by authors named "Seth Ettenberg"

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BOXR1030, an anti-GPC3 CAR with exogenous GOT2 expression, shows enhanced T cell metabolism and improved anti-cell line derived tumor xenograft activity.
Taylor L Hickman, Eugene Choi, Kathleen R Whiteman, Sujatha Muralidharan, Tapasya Pai, Seth A Ettenberg

PLoS One· May 2022

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Preclinical Antitumor Activity of a Novel Anti-c-KIT Antibody-Drug Conjugate against Mutant and Wild-type c-KIT-Positive Solid Tumors.
Tinya Abrams, Anu Connor, Christie Fanton, Steven B Cohen, Thomas Huber, Seth A Ettenberg

Clin Cancer Res· September 2018

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Discovery and Optimization of HKT288, a Cadherin-6-Targeting ADC for the Treatment of Ovarian and Renal Cancers.
Carl U Bialucha, Scott D Collins, Xiao Li, Parmita Saxena, Xiamei Zhang, Seth A Ettenberg

Cancer Discov· September 2017

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Microscale screening of antibody libraries as maytansinoid antibody-drug conjugates.
Kalli C Catcott, Molly A McShea, Carl Uli Bialucha, Kathy L Miller, Stuart W Hicks, Seth A Ettenberg

MAbs· December 2016

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Gene Expression Ratios Lead to Accurate and Translatable Predictors of DR5 Agonism across Multiple Tumor Lineages.
Anupama Reddy, Joseph D Growney, Nick S Wilson, Caroline M Emery, Jennifer A Johnson, Seth A Ettenberg

PLoS One· May 2016

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Correction: Gene Expression Ratios Lead to Accurate and Translatable Predictors of DR5 Agonism across Multiple Tumor Lineages.
Anupama Reddy, Joseph D Growney, Nick S Wilson, Caroline M Emery, Jennifer A Johnson, Seth A Ettenberg

PLoS One· April 2016

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Multivalent nanobodies targeting death receptor 5 elicit superior tumor cell killing through efficient caspase induction.
Heather A Huet, Joseph D Growney, Jennifer A Johnson, Jing Li, Sanela Bilic, Seth A Ettenberg

MAbs· September 2015

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Reversing LRP5-dependent osteoporosis and SOST deficiency-induced sclerosing bone disorders by altering WNT signaling activity.
Ming-Kang Chang, Ina Kramer, Hansjoerg Keller, Jonathan H Gooi, Corinne Collett, Seth A Ettenberg

J Bone Miner Res· January 2014

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Combination of antibody that inhibits ligand-independent HER3 dimerization and a p110α inhibitor potently blocks PI3K signaling and growth of HER2+ breast cancers.
Joan T Garrett, Cammie R Sutton, Richard Kurupi, Carl Uli Bialucha, Seth A Ettenberg

Cancer Res· October 2013

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An antibody that locks HER3 in the inactive conformation inhibits tumor growth driven by HER2 or neuregulin.
Andrew P Garner, Carl U Bialucha, Elizabeth R Sprague, Joan T Garrett, Qing Sheng, Seth A Ettenberg

Cancer Res· October 2013

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Activating Fc γ receptors contribute to the antitumor activities of immunoregulatory receptor-targeting antibodies.
Yannick Bulliard, Rose Jolicoeur, Maurice Windman, Sarah M Rue, Seth Ettenberg

J Exp Med· August 2013

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Inhibition of tumorigenesis driven by different Wnt proteins requires blockade of distinct ligand-binding regions by LRP6 antibodies.
Seth A Ettenberg, Olga Charlat, Michael P Daley, Shanming Liu, Karen J Vincent

Proc Natl Acad Sci U S A· August 2010

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An activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cells.
Qing Sheng, Xinggang Liu, Eleanor Fleming, Karen Yuan, Huiying Piao, Seth Ettenberg

Cancer Cell· March 2010

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Anti-DKK1 mAb (BHQ880) as a potential therapeutic agent for multiple myeloma.
Mariateresa Fulciniti, Pierfrancesco Tassone, Teru Hideshima, Sonia Vallet, Puru Nanjappa, Seth A Ettenberg

Blood· July 2009

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LC-MS/MS approach for quantification of therapeutic proteins in plasma using a protein internal standard and 2D-solid-phase extraction cleanup.
Ziping Yang, Michael Hayes, Xinping Fang, Michael P Daley, Seth Ettenberg

Anal Chem· December 2007

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Cbl-b interacts with ubiquitinated proteins; differential functions of the UBA domains of c-Cbl and Cbl-b.
Gareth C Davies, Seth A Ettenberg, Ashley O Coats, Mark Mussante, Sarangan Ravichandran

Oncogene· September 2004

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Evaluation of biologic end points and pharmacokinetics in patients with metastatic breast cancer after treatment with erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor.
Antoinette R Tan, Xiaowei Yang, Stephen M Hewitt, Arlene Berman, Erin R Lepper, Seth A Ettenberg

J Clin Oncol· August 2004

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WW domain HECT E3s target Cbl RING finger E3s for proteasomal degradation.
Alessandra Magnifico, Seth Ettenberg, Cuihong Yang, Jennifer Mariano, Swati Tiwari

J Biol Chem· October 2003

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