Publications by authors named "Severine Chaumont-Dubel"

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5-HT receptor neutral antagonists protect astrocytes: A lesson from 2-phenylpyrrole derivatives.
Marcin Drop, Paulina Koczurkiewicz-Adamczyk, Ophélie Bento, Wojciech Pietruś, Grzegorz Satała, Severine Chaumont-Dubel

Eur J Med Chem· September 2024

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Superiority of the Triple-Acting 5-HTR/5-HTR Antagonist and MAO-B Reversible Inhibitor over 5-HTR Antagonist Intepirdine in Alleviation of Cognitive Deficits in Rats.
Katarzyna Grychowska, Uriel López-Sánchez, Mathieu Vitalis, Geoffrey Canet, Grzegorz Satała, Séverine Chaumont-Dubel

J Med Chem· November 2023

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Spatiotemporal dynamics of 5-HT receptor ciliary localization during mouse brain development.
Vincent Dupuy, Matthieu Prieur, Anne Pizzoccaro, Clara Margarido, Emmanuel Valjent, Séverine Chaumont-Dubel

Neurobiol Dis· January 2023

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Impact of 5-HT Receptor Subcellular Localization on Its Signaling and Its Pathophysiological Roles.
Séverine Chaumont-Dubel, Sonya Galant, Matthieu Prieur, Tristan Bouschet, Joël Bockaert

Cells· January 2023

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Impact of the Substitution Pattern at the Basic Center and Geometry of the Amine Fragment on 5-HT and DR Affinity in the 1-Pyrrolo[3,2-]quinoline Series.
Katarzyna Grychowska, Wojciech Pietruś, Ludmiła Kulawik, Ophélie Bento, Grzegorz Satała, Séverine Chaumont-Dubel

Molecules· January 2023

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1-(Arylsulfonyl-isoindol-2-yl)piperazines as 5-HTR Antagonists: Mechanochemical Synthesis, In Vitro Pharmacological Properties and Glioprotective Activity.
Vittorio Canale, Wojciech Trybała, Séverine Chaumont-Dubel, Paulina Koczurkiewicz-Adamczyk, Grzegorz Satała

Biomolecules· December 2022

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A serotonergic axon-cilium synapse drives nuclear signaling to alter chromatin accessibility.
Shu-Hsien Sheu, Srigokul Upadhyayula, Vincent Dupuy, Song Pang, Fei Deng, Séverine Chaumont-Dubel

Cell· September 2022

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Early 5-HT receptor blockade prevents symptom onset in a model of adolescent cannabis abuse.
Coralie Berthoux, Al Mahdy Hamieh, Angelina Rogliardo, Emilie L Doucet, Camille Coudert, Séverine Chaumont-Dubel

EMBO Mol Med· September 2022

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Neuropathic pain-alleviating activity of novel 5-HT receptor inverse agonists derived from 2-aryl-1H-pyrrole-3-carboxamide.
Marcin Drop, Florian Jacquot, Vittorio Canale, Severine Chaumont-Dubel, Maria Walczak

Bioorg Chem· October 2021

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Structure-Based Design and Optimization of FPPQ, a Dual-Acting 5-HT and 5-HT Receptor Antagonist with Antipsychotic and Procognitive Properties.
Paweł Zajdel, Katarzyna Grychowska, Szczepan Mogilski, Rafał Kurczab, Grzegorz Satała, Séverine Chaumont-Dubel

J Med Chem· September 2021

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Novel and atypical pathways for serotonin signaling.
Joël Bockaert, Carine Bécamel, Séverine Chaumont-Dubel, Sylvie Claeysen, Franck Vandermoere

Fac Rev· June 2021

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2-Phenyl-1-pyrrole-3-carboxamide as a New Scaffold for Developing 5-HT Receptor Inverse Agonists with Cognition-Enhancing Activity.
Marcin Drop, Vittorio Canale, Séverine Chaumont-Dubel, Rafał Kurczab, Grzegorz Satała

ACS Chem Neurosci· April 2021

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Amelioration of Tau pathology and memory deficits by targeting 5-HT7 receptor.
Josephine Labus, Kian-Fritz Röhrs, Jana Ackmann, Hristo Varbanov, Franziska E Müller, Séverine Chaumont-Dubel

Prog Neurobiol· February 2021

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International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function.
Nicholas M Barnes, Gerard P Ahern, Carine Becamel, Joël Bockaert, Michael Camilleri, Severine Chaumont-Dubel

Pharmacol Rev· January 2021

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Imidazopyridine-Based 5-HT Receptor Neutral Antagonists: Impact of -Benzyl and -Phenylsulfonyl Fragments on Different Receptor Conformational States.
David Vanda, Vittorio Canale, Severine Chaumont-Dubel, Rafał Kurczab, Grzegorz Satała

J Med Chem· January 2021

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A dual-acting 5-HT receptor inverse agonist/MAO-B inhibitor displays glioprotective and pro-cognitive properties.
Vittorio Canale, Katarzyna Grychowska, Rafał Kurczab, Mateusz Ryng, Abdul Raheem Keeri, Severine Chaumont-Dubel

Eur J Med Chem· December 2020

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mTOR activation by constitutively active serotonin6 receptors as new paradigm in neuropathic pain and its treatment.
Pierre-Yves Martin, Stéphane Doly, Al Mahdy Hamieh, Eric Chapuy, Vittorio Canale, Séverine Chaumont-Dubel

Prog Neurobiol· October 2020

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The atypical chemokine receptor 3 interacts with Connexin 43 inhibiting astrocytic gap junctional intercellular communication.
Amos Fumagalli, Joyce Heuninck, Anne Pizzoccaro, Enora Moutin, Joyce Koenen, Séverine Chaumont-Dubel

Nat Commun· September 2020

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The 5-HT receptor interactome: New insight in receptor signaling and its impact on brain physiology and pathologies.
Séverine Chaumont-Dubel, Vincent Dupuy, Joël Bockaert, Carine Bécamel, Philippe Marin

Neuropharmacology· August 2020

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Early 5-HT receptor blockade prevents symptom onset in a model of adolescent cannabis abuse.
Coralie Berthoux, Al Mahdy Hamieh, Angelina Rogliardo, Emilie L Doucet, Camille Coudert, Séverine Chaumont-Dubel

EMBO Mol Med· May 2020

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Dynamic interactions of the 5-HT receptor with protein partners control dendritic tree morphogenesis.
Camille N Pujol, Vincent Dupuy, Martial Séveno, Leonie Runtz, Joël Bockaert, Séverine Chaumont-Dubel

Sci Signal· February 2020

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Dual 5-HT and D Receptor Antagonists in a Group of 1-Pyrrolo[3,2-]quinolines with Neuroprotective and Procognitive Activity.
Katarzyna Grychowska, Severine Chaumont-Dubel, Rafał Kurczab, Paulina Koczurkiewicz, Caroline Deville

ACS Chem Neurosci· July 2019

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Novel non-sulfonamide 5-HT receptor partial inverse agonist in a group of imidazo[4,5-b]pyridines with cognition enhancing properties.
David Vanda, Miroslav Soural, Vittorio Canale, Séverine Chaumont-Dubel, Grzegorz Satała

Eur J Med Chem· January 2018

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Physical interaction between neurofibromin and serotonin 5-HT6 receptor promotes receptor constitutive activity.
Wissem Deraredj Nadim, Séverine Chaumont-Dubel, Fahima Madouri, Laetitia Cobret, Marie-Ludivine De Tauzia

Proc Natl Acad Sci U S A· October 2016

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Novel 1H-Pyrrolo[3,2-c]quinoline Based 5-HT6 Receptor Antagonists with Potential Application for the Treatment of Cognitive Disorders Associated with Alzheimer's Disease.
Katarzyna Grychowska, Grzegorz Satała, Tomasz Kos, Anna Partyka, Evelina Colacino, Severine Chaumont-Dubel

ACS Chem Neurosci· July 2016

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