Publications by authors named "Shafagh A Waters"

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In silico, in vitro and ex vivo characterization of cystic fibrosis transmembrane conductance regulator pathogenic variants localized in the fourth intracellular loop and their rescue by modulators.
Emanuela Pesce, Valeria Tomati, Valeria Capurro, Mariateresa Lena, Cristina Pastorino, Shafagh A Waters

Br J Pharmacol· December 2025

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Gene-Corrected Basal Cells Restore CFTR In Vitro; Transplants Regenerate Epithelium in a Preclinical Sinus Model.
Katelin M Allan, Shaoyan Zhang, Sharon L Wong, Alexander Capraro, Alexandra McCarron, Shafagh A Waters

bioRxiv· July 2025

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The equitable challenges to quality use of modulators for cystic fibrosis in Australia.
Laura K Fawcett, Shafagh A Waters, Adam Jaffe

Med J Aust· January 2025

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Beyond insulin: Unraveling the complex interplay of ER stress, oxidative damage, and CFTR modulation in CFRD.
Bala Umashankar, Lena Eliasson, Chee Y Ooi, Ki Wook Kim, James A M Shaw, Shafagh A Waters

J Cyst Fibros· September 2024

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Incomplete transcriptional dosage compensation of chicken and platypus sex chromosomes is balanced by post-transcriptional compensation.
Nicholas C Lister, Ashley M Milton, Hardip R Patel, Shafagh A Waters, Benjamin J Hanrahan, Paul D Waters

Proc Natl Acad Sci U S A· August 2024

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Uncovering strain- and age-dependent innate immune responses to SARS-CoV-2 infection in air-liquid-interface cultured nasal epithelia.
Jessie J-Y Chang, Samantha L Grimley, Bang M Tran, Georgia Deliyannis, Carolin Tumpach, Shafagh A Waters

iScience· June 2024

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Identification of the RSX interactome in a marsupial shows functional coherence with the Xist interactome during X inactivation.
Kim L McIntyre, Shafagh A Waters, Ling Zhong, Gene Hart-Smith, Mark Raftery, Paul D Waters

Genome Biol· May 2024

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Hierarchical assembly of tryptophan zipper peptides into stress-relaxing bioactive hydrogels.
Ashley K Nguyen, Thomas G Molley, Egi Kardia, Sylvia Ganda, Sudip Chakraborty, Shafagh A Waters

Nat Commun· October 2023

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Q1291H-CFTR molecular dynamics simulations and theratyping in nasal epithelial models and clinical response to elexacaftor/tezacaftor/ivacaftor in a Q1291H/F508del patient.
Katelin M Allan, Miro A Astore, Egi Kardia, Sharon L Wong, Laura K Fawcett, Shafagh A Waters

Front Mol Biosci· June 2023

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Comparing Cytology Brushes for Optimal Human Nasal Epithelial Cell Collection: Implications for Airway Disease Diagnosis and Research.
Laura K Fawcett, Nihan Turgutoglu, Katelin M Allan, Yvonne Belessis, John Widger, Shafagh A Waters

J Pers Med· May 2023

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Assessment of Pre-Clinical Liver Models Based on Their Ability to Predict the Liver-Tropism of Adeno-Associated Virus Vectors.
Adrian Westhaus, Marti Cabanes-Creus, Kimberley L Dilworth, Erhua Zhu, David Salas Gómez, Shafagh A Waters

Hum Gene Ther· April 2023

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Gas-modulating microcapsules for spatiotemporal control of hypoxia.
Thomas G Molley, Shouyuan Jiang, Louis Ong, Chantal Kopecky, Chavinya D Ranaweera, Shafagh A Waters

Proc Natl Acad Sci U S A· April 2023

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Molecular and Functional Characteristics of Airway Epithelium under Chronic Hypoxia.
Sharon L Wong, Egi Kardia, Abhishek Vijayan, Bala Umashankar, Elvis Pandzic, Shafagh A Waters

Int J Mol Sci· March 2023

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S945L-CFTR molecular dynamics, functional characterization and tezacaftor/ivacaftor efficacy and in matched pediatric patient-derived cell models.
Katelin M Allan, Miro A Astore, Laura K Fawcett, Sharon L Wong, Po-Chia Chen, Shafagh A Waters

Front Pediatr· November 2022

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Quantifying Intracellular Viral Pathogen: Specimen Preparation, Visualization and Quantification of Multiple Immunofluorescent Signals in Fixed Human Airway Epithelium Cultured at Air-Liquid Interface.
Sharon L Wong, Elvis Pandzic, Egi Kardia, Katelin M Allan, Renee M Whan, Shafagh A Waters

J Pers Med· October 2022

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Molecular Dynamics and Theratyping in Airway and Gut Organoids Reveal R352Q-CFTR Conductance Defect.
Sharon L Wong, Nikhil T Awatade, Miro A Astore, Katelin M Allan, Michael J Carnell, Shafagh A Waters

Am J Respir Cell Mol Biol· July 2022

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Air-Liquid-Interface Differentiated Human Nose Epithelium: A Robust Primary Tissue Culture Model of SARS-CoV-2 Infection.
Bang M Tran, Samantha L Grimley, Julie L McAuley, Abderrahman Hachani, Linda Earnest, Shafagh A Waters

Int J Mol Sci· January 2022

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Molecular dynamics and functional characterization of I37R-CFTR lasso mutation provide insights into channel gating activity.
Sharon L Wong, Nikhil T Awatade, Miro A Astore, Katelin M Allan, Michael J Carnell, Shafagh A Waters

iScience· January 2022

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Collection, Expansion, and Differentiation of Primary Human Nasal Epithelial Cell Models for Quantification of Cilia Beat Frequency.
Katelin M Allan, Sharon L Wong, Laura K Fawcett, Alexander Capraro, Adam Jaffe, Shafagh A Waters

J Vis Exp· November 2021

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Integrative resource for network-based investigation of COVID-19 combinatorial drug repositioning and mechanism of action.
A K M Azad, Shadma Fatima, Alexander Capraro, Shafagh A Waters, Fatemeh Vafaee

Patterns (N Y)· September 2021

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Multi-omics of the esophageal microenvironment identifies signatures associated with progression of Barrett's esophagus.
Nandan P Deshpande, Stephen M Riordan, Claire J Gorman, Shaun Nielsen, Tonia L Russell, Shafagh A Waters

Genome Med· August 2021

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Significant functional differences in differentiated Conditionally Reprogrammed (CRC)- and Feeder-free Dual SMAD inhibited-expanded human nasal epithelial cells.
Nikhil T Awatade, Sharon L Wong, Alexander Capraro, Elvis Pandzic, Iveta Slapetova, Shafagh A Waters

J Cyst Fibros· March 2021

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Treatment of Cystic Fibrosis: From Gene- to Cell-Based Therapies.
Katelin M Allan, Nigel Farrow, Martin Donnelley, Adam Jaffe, Shafagh A Waters

Front Pharmacol· March 2021

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Mesenchymal Stem Cell exosome delivered Zinc Finger Protein activation of cystic fibrosis transmembrane conductance regulator.
Olga Villamizar, Shafagh A Waters, Tristan Scott, Nicole Grepo, Adam Jaffe

J Extracell Vesicles· January 2021

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Avatar acceptability: views from the Australian Cystic Fibrosis community on the use of personalised organoid technology to guide treatment decisions.
Laura K Fawcett, Claire E Wakefield, Sheila Sivam, Peter G Middleton, Peter Wark, Shafagh A Waters

ERJ Open Res· January 2021

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