Publications by authors named "Shailly Mehrotra"

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Pharmacological Characterization of Zasocitinib (TAK-279): An Oral, Highly Selective, and Potent Allosteric TYK2 Inhibitor.
Shailly Mehrotra, Yasuyo Sano, Petro Halkowycz, Elizabeth Wilson, Chandra Durairaj

J Invest Dermatol· January 2026

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Population pharmacokinetic modeling of vedolizumab for graft-versus-host disease prophylaxis in adults with allogeneic hematopoietic stem cell transplant.
Timothy Waterhouse, Kyle Baron, Westley Eure, Chunlin Chen, Nathanael L Dirks, Shailly Mehrotra

Pharmacol Res Perspect· October 2024

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ENTERPRET: A Randomized Controlled Trial of Vedolizumab Dose Optimization in Patients With Ulcerative Colitis Who Have Early Nonresponse.
Vipul Jairath, Andres Yarur, Mark T Osterman, Alexandra James, Diane Balma, Shailly Mehrotra

Clin Gastroenterol Hepatol· May 2024

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Randomized clinical trial: A phase 2b controlled study of the efficacy and safety of trazpiroben (TAK-906) for idiopathic or diabetic gastroparesis.
Jan Tack, Richard McCallum, Braden Kuo, Susanna Y Huh, Yanwei Zhang, Shailly Mehrotra

Neurogastroenterol Motil· October 2023

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Neurotransmitter transporter occupancy following administration of centanafadine sustained-release tablets: A phase 1 study in healthy male adults.
David Matuskey, Jean-Dominique Gallezot, Nabeel Nabulsi, Shannan Henry, Kristen Torres, Shailly Mehrotra

J Psychopharmacol· February 2023

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Extrapolation of Efficacy from Adults to Pediatric Patients of Drugs for Treatment of Partial Onset Seizures: A Regulatory Perspective.
Shailly Mehrotra, Atul Bhattaram, Kevin Krudys, Michael Bewernitz, Ramana Uppoor

Clin Pharmacol Ther· October 2022

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Pediatric formulation development - Challenges of today and strategies for tomorrow: Summary report from M-CERSI workshop 2019.
David Cheng Thiam Tan, Yuet Mei Khong, Steven Mount, Elizabeth Galella, Biplob Mitra, Shailly Mehrotra

Eur J Pharm Biopharm· July 2021

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Harnessing formulation and clinical pharmacology knowledge for efficient pediatric drug development: Overview and discussions from M-CERSI pediatric formulation workshop 2019.
Yuet Mei Khong, Jing Liu, Jack Cook, Vivek Purohit, Karen Thompson, Shailly Mehrotra

Eur J Pharm Biopharm· July 2021

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Personalized Management of Chemotherapy-Induced Peripheral Neuropathy Based on a Patient Reported Outcome: CALGB 40502 (Alliance).
Manish R Sharma, Shailly Mehrotra, Elizabeth Gray, Kehua Wu, William T Barry

J Clin Pharmacol· April 2020

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Population pharmacokinetics and exposure-response assessment of veliparib co-administered with temozolomide in patients with myeloid leukemias.
Renu Singh, Shailly Mehrotra, Mathangi Gopalakrishnan, Ivana Gojo, Judith E Karp

Cancer Chemother Pharmacol· February 2019

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Single-Dose Pharmacokinetics of HLD200, a Delayed-Release and Extended-Release Methylphenidate Formulation, in Healthy Adults and in Adolescents and Children with Attention-Deficit/Hyperactivity Disorder.
Ann Childress, Shailly Mehrotra, Jogarao Gobburu, Angus McLean, Norberto J DeSousa

J Child Adolesc Psychopharmacol· February 2018

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Exposure-Response of Veliparib to Inform Phase II Trial Design in Refractory or Relapsed Patients with Hematological Malignancies.
Shailly Mehrotra, Mathangi Gopalakrishnan, Jogarao Gobburu, Jiuping Ji, Jacqueline M Greer

Clin Cancer Res· November 2017

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Kinetic-Pharmacodynamic Model of Chemotherapy-Induced Peripheral Neuropathy in Patients with Metastatic Breast Cancer Treated with Paclitaxel, Nab-Paclitaxel, or Ixabepilone: CALGB 40502 (Alliance).
Shailly Mehrotra, Manish R Sharma, Elizabeth Gray, Kehua Wu, William T Barry

AAPS J· September 2017

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Population pharmacokinetics and site of action exposures of veliparib with topotecan plus carboplatin in patients with haematological malignancies.
Shailly Mehrotra, Mathangi Gopalakrishnan, Jogarao Gobburu, Jacqueline M Greer, Richard Piekarz

Br J Clin Pharmacol· August 2017

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Parent-Metabolite Pharmacokinetic Modeling and Pharmacodynamics of Veliparib (ABT-888), a PARP Inhibitor, in Patients With BRCA 1/2-Mutated Cancer or PARP-Sensitive Tumor Types.
Jing Niu, Christie Scheuerell, Shailly Mehrotra, Sharon Karan, Shannon Puhalla

J Clin Pharmacol· August 2017

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Ceftolozane-Tazobactam Pharmacokinetics in a Critically Ill Patient on Continuous Venovenous Hemofiltration.
Wesley D Oliver, Emily L Heil, Jeffrey P Gonzales, Shailly Mehrotra, Kathryn Robinett

Antimicrob Agents Chemother· December 2015

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Pharmacometrics-guided drug development of antihyperhidrosis agents.
Shailly Mehrotra, Virginia D Schmith, Teodora Pene Dumitrescu, Jogarao Gobburu

J Clin Pharmacol· November 2015

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Don't get boxed in: commentary on the visual inspection practices to assess exposure-response relationships from binary clinical variables.
Shailly Mehrotra, Jeffry Florian, Jogarao Gobburu

J Clin Pharmacol· December 2012

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