Publications by authors named "Shankar Gharge"

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Modulating glucose homeostasis via expression of PPAR-γ TF: Pharmacological insights into quinolone-based hydrazones.
Naik Jui Pravin, Rohini S Kavalapure, Shankar Gharge, Shankar G Alegaon, Shriram D Ranade

Eur J Med Chem· December 2025

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Structure-guided development of Quinoline derivatives targeting kinesin spindle protein.
Rohini S Kavalapure, Shankar G Alegaon, Shankar Gharge, Shriram D Ranade, Sachin Gudasi

Bioorg Med Chem Lett· September 2025

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Exploring the anti-obesity potential of Ailanthus excelsa Roxb in vitro enzymatic inhibition and computational pharmacology insights.
Sachin Gudasi, M B Patil, Shankar Gharge, Shriram D Ranade, Hannah Lalengzuali Fanai

Sci Rep· September 2025

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Synthesis and Biological Evaluation of Quinolone-Based Hydrazones as Potential Antidiabetic Agents Targeting Key Metabolic Enzymes.
Naik Jui Pravin, Rohini S Kavalapure, Shankar Gharge, Shankar G Alegaon, Shriram D Ranade

ACS Omega· August 2025

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Computational and experimental repositioning of quinoline analogues as KSP inhibitors: insights from free energy landscape and PCA analysis.
Shankar G Alegaon, Shriram D Ranade, Shankar Gharge, Rohini S Kavalapure, Venkatasubramanian Ulaganathan

J Comput Aided Mol Des· August 2025

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Design, synthesis and molecular dynamics simulations of thiazole-based hydrazones targeting MDA-MB-231 breast cancer cells.
Shankar G Alegaon, Shankar Gharge, Sunidhi Patil, Sachin Gudasi, Shriram D Ranade

Bioorg Chem· April 2025

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Novel rhodanine-thiazole hybrids as potential antidiabetic agents: a structure-based drug design approach.
Shankar Gharge, Shankar G Alegaon, Shriram D Ranade, Rohini S Kavalapure, B R Prashantha Kumar

RSC Med Chem· February 2025

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Indoles as promising Therapeutics: A review of recent drug discovery efforts.
Naik Jui Pravin, Rohini S Kavalapure, Shankar G Alegaon, Shankar Gharge, Shriram D Ranade

Bioorg Chem· January 2025

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Molecular hybridization, synthesis, in vitro α-glucosidase inhibition, in vivo antidiabetic activity and computational studies of isatin based compounds.
Sunidhi Patil, Shankar G Alegaon, Shankar Gharge, Shriram D Ranade, Nayeem A Khatib

Bioorg Chem· December 2024

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Reversal of insulin resistance to combat type 2 diabetes mellitus by newer thiazolidinedione's in fructose induced insulin resistant rats.
Shriram D Ranade, Shankar G Alegaon, Nayeem A Khatib, Shankar Gharge, Rohini S Kavalapure

Eur J Med Chem· December 2024

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Expression of PPAR-γ TF by newly synthesized thiazolidine-2,4-diones to manage glycemic control: Insights from in silico, in vitro and experimental pharmacology in wistar rats.
Shankar Gharge, Shankar G Alegaon, Shriram D Ranade, Rohini S Kavalapure, B R Prashantha Kumar

Bioorg Chem· December 2024

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Quinoline-based Schiff bases as possible antidiabetic agents: ligand-based pharmacophore modeling, 3D QSAR, docking, and molecular dynamics simulations study.
Shriram D Ranade, Shankar G Alegaon, Nayeem A Khatib, Shankar Gharge, Rohini S Kavalapure

RSC Med Chem· July 2024

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Exploring In-Silico, In-Vitro Antioxidant, and Cytotoxic Potential of Valerian wallichii by On Cervical Epithelial Carcinoma (HeLa) Cell Lines.
Sachin Gudasi, Shankar Gharge, Rahul Koli, Pooja Kagawad

Chem Biodivers· March 2024

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