Publications by authors named "Shriram D Ranade"

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Modulating glucose homeostasis via expression of PPAR-γ TF: Pharmacological insights into quinolone-based hydrazones.
Naik Jui Pravin, Rohini S Kavalapure, Shankar Gharge, Shankar G Alegaon, Shriram D Ranade

Eur J Med Chem· December 2025

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Structure-guided development of Quinoline derivatives targeting kinesin spindle protein.
Rohini S Kavalapure, Shankar G Alegaon, Shankar Gharge, Shriram D Ranade, Sachin Gudasi

Bioorg Med Chem Lett· September 2025

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Exploring the anti-obesity potential of Ailanthus excelsa Roxb in vitro enzymatic inhibition and computational pharmacology insights.
Sachin Gudasi, M B Patil, Shankar Gharge, Shriram D Ranade, Hannah Lalengzuali Fanai

Sci Rep· September 2025

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Synthesis and Biological Evaluation of Quinolone-Based Hydrazones as Potential Antidiabetic Agents Targeting Key Metabolic Enzymes.
Naik Jui Pravin, Rohini S Kavalapure, Shankar Gharge, Shankar G Alegaon, Shriram D Ranade

ACS Omega· August 2025

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Computational and experimental repositioning of quinoline analogues as KSP inhibitors: insights from free energy landscape and PCA analysis.
Shankar G Alegaon, Shriram D Ranade, Shankar Gharge, Rohini S Kavalapure, Venkatasubramanian Ulaganathan

J Comput Aided Mol Des· August 2025

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Design, synthesis and molecular dynamics simulations of thiazole-based hydrazones targeting MDA-MB-231 breast cancer cells.
Shankar G Alegaon, Shankar Gharge, Sunidhi Patil, Sachin Gudasi, Shriram D Ranade

Bioorg Chem· April 2025

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Targeting cardiotoxicity: the potential of L. in doxorubicin therapy.
Kshitij A Lele, Priyanka P Patil, Sneha V Kakade, Naveen R Maledavar, Shriram D Ranade

In Silico Pharmacol· March 2025

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Novel rhodanine-thiazole hybrids as potential antidiabetic agents: a structure-based drug design approach.
Shankar Gharge, Shankar G Alegaon, Shriram D Ranade, Rohini S Kavalapure, B R Prashantha Kumar

RSC Med Chem· February 2025

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Indoles as promising Therapeutics: A review of recent drug discovery efforts.
Naik Jui Pravin, Rohini S Kavalapure, Shankar G Alegaon, Shankar Gharge, Shriram D Ranade

Bioorg Chem· January 2025

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Molecular hybridization, synthesis, in vitro α-glucosidase inhibition, in vivo antidiabetic activity and computational studies of isatin based compounds.
Sunidhi Patil, Shankar G Alegaon, Shankar Gharge, Shriram D Ranade, Nayeem A Khatib

Bioorg Chem· December 2024

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Reversal of insulin resistance to combat type 2 diabetes mellitus by newer thiazolidinedione's in fructose induced insulin resistant rats.
Shriram D Ranade, Shankar G Alegaon, Nayeem A Khatib, Shankar Gharge, Rohini S Kavalapure

Eur J Med Chem· December 2024

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Expression of PPAR-γ TF by newly synthesized thiazolidine-2,4-diones to manage glycemic control: Insights from in silico, in vitro and experimental pharmacology in wistar rats.
Shankar Gharge, Shankar G Alegaon, Shriram D Ranade, Rohini S Kavalapure, B R Prashantha Kumar

Bioorg Chem· December 2024

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Quinoline-based Schiff bases as possible antidiabetic agents: ligand-based pharmacophore modeling, 3D QSAR, docking, and molecular dynamics simulations study.
Shriram D Ranade, Shankar G Alegaon, Nayeem A Khatib, Shankar Gharge, Rohini S Kavalapure

RSC Med Chem· July 2024

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Design, synthesis, molecular dynamics simulation, MM/GBSA studies and kinesin spindle protein inhibitory evaluation of some 4-aminoquinoline hybrids.
Shriram D Ranade, Shankar G Alegaon, U Venkatasubramanian, A Soundarya Priya, Rohini S Kavalapure

Comput Biol Chem· August 2023

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Synthesis, molecular docking and ADME studies of thiazole-thiazolidinedione hybrids as antimicrobial agents.
Shankar G Alegaon, Venkatasubramanian U, K R Alagawadi, Dushyant Kumar, Rohini S Kavalapure, Shriram D Ranade

J Biomol Struct Dyn· September 2022

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Design, synthesis, and molecular docking study of some 2-((7-chloroquinolin-4-yl) amino) benzohydrazide Schiff bases as potential Eg5 inhibitory agents.
Rohini S Kavalapure, Shankar G Alegaon, U Venkatasubramanian, A Soundarya Priya, Shriram D Ranade

Bioorg Chem· November 2021

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