Publications by authors named "Shaomeng Wang"

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Terahertz Amplification Induced by Electron-Phonon Interactions in Gated Graphene Plasmonic System.
Zijian Qiu, Shengpeng Yang, Sunchao Huang, Shaomeng Wang, Ping Zhang

Research (Wash D C)· December 2025

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Albumin nanocomplex of BCL-2/xL inhibitor reduced platelet toxicity and improved anticancer efficacy in myeloproliferative neoplasm and lymphoma.
Hongxiang Hu, Chengyi Li, Yudong Song, Jizhao Xie, Qiuxia Li, Shaomeng Wang

Biomaterials· November 2025

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PROTACs therapeutically target the polyglutamine androgen receptor in spinal and bulbar muscular atrophy models.
Agamjot Sangotra, Satya L Reddy, Curtis J Kuo, Weiguo Xiang, Diane E Merry, Shaomeng Wang

Neurotherapeutics· October 2025

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Targeting histone H2B acetylated enhanceosomes via p300/CBP degradation in prostate cancer.
Jie Luo, Zhixiang Chen, Yuanyuan Qiao, Jean Ching-Yi Tien, Eleanor Young, Rui Wang, Mi Wang, Shaomeng Wang

Nat Genet· October 2025

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RAS mutation-specific responses to paralog- and state-selective RAS inhibitors.
Beau Baars, Ana Orive-Ramos, Matthew J Emmett, Bijaya Gaire, Mathieu Desaunay, Shaomeng Wang

Mol Cancer Res· October 2025

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Thermionics in Topological Materials.
Sunchao Huang, Zihao Zhang, Youfeng Yang, Yuan Zheng, Abdullah Al-Mamun, Shaomeng Wang

Adv Mater· September 2025

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Discovery of a Novel Series of -Indolinone-Based Glutarimides as Highly Efficacious and Selective IKZF2 Molecular Glue Degraders.
Xuqing Zhang, Harshil Dhruv, Qiaolin Deng, Matthew Tudor, Nelisa Bechtel, Shaomeng Wang

J Med Chem· September 2025

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Terahertz waves promote Ca transport in the Ca2.1 channel.
Yuankun Sun, Yangmei Li, Yaxiong Yang, Shaomeng Wang, Yubin Gong

Spectrochim Acta A Mol Biomol Spectrosc· August 2025

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Streptococcus pneumoniae synchronizes the states of cell wall peptidoglycan acetylation and genome methylation by programmed DNA inversions.
Xiu-Yuan Li, Ping He, Shaomeng Wang, Yusong Wang, Dingfei Yan, Juanjuan Wang

PLoS Pathog· August 2025

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Novel, potent, and orally bioavailable LSD1 inhibitors induce fetal hemoglobin synthesis in a sickle cell disease mouse model.
Yu Wang, Lei Yu, Kaiwen Deng, Mathivanan Packiarajan, Angelo Aguilar, Shaomeng Wang

Blood· July 2025

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STAT5 and STAT3 balance shapes dendritic cell function and tumour immunity.
Jiajia Zhou, Kole Tison, Haibin Zhou, Longchuan Bai, Ranjan Kumar Acharyya, Yu Wang, Shaomeng Wang

Nature· July 2025

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MD-4251: A First-in-Class Oral MDM2 Degrader Inducing Complete Tumor Regression with Single-Dose Administration.
Ranjan Kumar Acharyya, Liyue Huang, Angelo Aguilar, Biao Hu, Longchuan Bai, Yu Wang, Shaomeng Wang

J Med Chem· July 2025

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Discovery and Characterization of PVTX-321 as a Potent and Orally Bioavailable Estrogen Receptor Degrader for ER+/HER2- Breast Cancer.
Guozhang Xu, Courtney G Havens, Qiaolin Deng, Cassandra Lowenstein, Debangshu Samanta, Shaomeng Wang

J Med Chem· June 2025

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Development of PVTX-405 as a potent and highly selective molecular glue degrader of IKZF2 for cancer immunotherapy.
Zhixiang Chen, Harshil Dhruv, Xuqing Zhang, Rohan Kalyan Rej, Longchuan Bai, Meilin Wang, Shaomeng Wang

Nat Commun· May 2025

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Correction to "Discovery of ERD-1233 as a Potent and Orally Efficacious Estrogen Receptor PROTAC Degrader for the Treatment of ER+ Human Breast Cancer".
Ranjan Kumar Acharyya, Rohan Kalyan Rej, Biao Hu, Zhixiang Chen, Dimin Wu, Yu Wang, Shaomeng Wang

J Med Chem· April 2025

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RAS mutation-specific signaling dynamics in response to paralog- and state- selective RAS inhibitors.
Beau Baars, Ana Orive-Ramos, Ziyue Kou, Bijaya Gaire, Mathieu Desaunay, Shaomeng Wang

bioRxiv· March 2025

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Discovery of Potent, Highly Selective, and Efficacious SMARCA2 Degraders.
Zhenwu Li, Lalgudi S Harikrishnan, Guozhang Xu, Debangshu Samanta, Jose C Clemente, Mi Wang, Shaomeng Wang

J Med Chem· January 2025

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Discovery of High-Affinity SMARCA2/4 Bromodomain Ligands and Development of Potent and Exceptionally Selective SMARCA2 PROTAC Degraders.
Lingying Leng, Wenbin Tu, Lin Yang, Liyue Huang, Mi Wang, Shaomeng Wang

J Med Chem· January 2025

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Discovery of SMD-3236: A Potent, Highly Selective and Efficacious SMARCA2 Degrader for the Treatment of SMARC4-Deficient Human Cancers.
Lin Yang, Wenbin Tu, Lingying Leng, Liyue Huang, Wei Jiang, Mi Wang, Yu Wang, Meilin Wang, Shaomeng Wang

J Med Chem· January 2025

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Multidimensional analyses identify genes of high priority for pancreatic cancer research.
Zeribe C Nwosu, Heather M Giza, Maya Nassif, Verodia Charlestin, Rosa E Menjivar, Shaomeng Wang

JCI Insight· January 2025

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Itaconate transporter SLC13A3 impairs tumor immunity via endowing ferroptosis resistance.
Heng Lin, Kole Tison, Yuheng Du, Paul Kirchhoff, Chan Kim, Weichao Wang, Shaomeng Wang

Cancer Cell· December 2024

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Discovery of ERD-12310A as an Exceptionally Potent and Orally Efficacious PROTAC Degrader of Estrogen Receptor α (ERα).
Rohan Kalyan Rej, Biao Hu, Zhixiang Chen, Ranjan Kumar Acharyya, Dimin Wu, Yu Wang, Meilin Wang, Shaomeng Wang

J Med Chem· December 2024

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Terahertz Wave Alleviates Comorbidity Anxiety in Pain by Reducing the Binding Capacity of Nanostructured Glutamate Molecules to GluA2.
Zihua Song, Yuankun Sun, Pan Liu, Hao Ruan, Yuanyuan He, Shaomeng Wang

Research (Wash D C)· December 2024

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The SpxA1-TenA toxin-antitoxin system regulates epigenetic variations of Streptococcus pneumoniae by targeting protein synthesis.
Shaomeng Wang, Xiu-Yuan Li, Mengran Zhu, Haiteng Deng, Juanjuan Wang

PLoS Pathog· December 2024

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Proteolysis-targeting vaccines (PROTAVs) for robust combination immunotherapy of melanoma.
Qiyan Wang, Ting Su, Furong Cheng, Shurong Zhou, Xiang Liu, Mi Wang, Shaomeng Wang

bioRxiv· November 2024

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