Publications by authors named "Sharan R Srinivasan"

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Practice Recommendations for Genetic Testing of Ataxias.
Sharan R Srinivasan, Amy D Mook, Michelle Rochman, Jin Yun Helen Chen, Weiyi Mu

Ann Clin Transl Neurol· December 2025

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Spinocerebellar Ataxia Progression Measured with the Patient-Reported Outcome Measure of Ataxia.
Anna L Burt, Gilbert L'Italien, Susan L Perlman, Liana S Rosenthal, Sheng-Han Kuo, Sharan R Srinivasan

Mov Disord· May 2025

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Fatigue Impacts Quality of Life in People with Spinocerebellar Ataxias.
Ruo-Yah Lai, Christian Rummey, Christian J Amlang, Chi-Ying R Lin, Tiffany X Chen, Sharan R Srinivasan

Mov Disord Clin Pract· May 2024

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Gerstmann-Sträussler-Scheinker Disease Presenting as Late-Onset Slowly Progressive Spinocerebellar Ataxia, and Comparative Case Series with Neuropathology.
Christopher D Stephen, Claudio Melo de Gusmao, Sharan R Srinivasan, Abby Olsen, Fernando Freua

Mov Disord Clin Pract· April 2024

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Clinical Trial-Ready Patient Cohorts for Multiple System Atrophy: Coupling Biospecimen and iPSC Banking to Longitudinal Deep-Phenotyping.
Alain Ndayisaba, Ariana T Pitaro, Andrew S Willett, Kristie A Jones, Claudio Melo de Gusmao, Sharan R Srinivasan

Cerebellum· February 2024

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Correction to: Clinical trial-ready patient cohorts for multiple system atrophy: coupling biospecimen and iPSC banking to longitudinal deep-phenotyping.
Alain Ndayisaba, Ariana T Pitaro, Ashlan S Willett, Kristie A Jones, Claudio Melo de Gusmao, Sharan R Srinivasan

Cerebellum· February 2024

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Targeting Circuit Abnormalities in Neurodegenerative Disease.
Sharan Ram Srinivasan

Mol Pharmacol· January 2023

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Discovery of Novel Activators of Large-Conductance Calcium-Activated Potassium Channels for the Treatment of Cerebellar Ataxia.
Sharan R Srinivasan, Haoran Huang, Wei-Chih Chang, Joshua A Nasburg, Hai M Nguyen

Mol Pharmacol· July 2022

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Moving Towards Therapy in SCA1: Insights from Molecular Mechanisms, Identification of Novel Targets, and Planning for Human Trials.
Sharan R Srinivasan, Vikram G Shakkottai

Neurotherapeutics· October 2019

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X-linked inhibitor of apoptosis protein (XIAP) is a client of heat shock protein 70 (Hsp70) and a biomarker of its inhibition.
Laura C Cesa, Hao Shao, Sharan R Srinivasan, Eric Tse, Chetali Jain

J Biol Chem· February 2018

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Heat Shock Protein 70 (Hsp70) Suppresses RIP1-Dependent Apoptotic and Necroptotic Cascades.
Sharan R Srinivasan, Laura C Cesa, Xiaokai Li, Olivier Julien, Min Zhuang

Mol Cancer Res· January 2018

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Stabilizing the Hsp70-Tau Complex Promotes Turnover in Models of Tauopathy.
Zapporah T Young, Jennifer N Rauch, Victoria A Assimon, Umesh K Jinwal, Misol Ahn, Sharan R Srinivasan

Cell Chem Biol· August 2016

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Analogs of the Allosteric Heat Shock Protein 70 (Hsp70) Inhibitor, MKT-077, as Anti-Cancer Agents.
Xiaokai Li, Sharan R Srinivasan, Jamie Connarn, Atta Ahmad, Zapporah T Young

ACS Med Chem Lett· November 2013

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Synthesis and initial evaluation of YM-08, a blood-brain barrier permeable derivative of the heat shock protein 70 (Hsp70) inhibitor MKT-077, which reduces tau levels.
Yoshinari Miyata, Xiaokai Li, Hsiu-Fang Lee, Umesh K Jinwal, Sharan R Srinivasan

ACS Chem Neurosci· June 2013

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Molecular chaperones DnaK and DnaJ share predicted binding sites on most proteins in the E. coli proteome.
Sharan R Srinivasan, Anne T Gillies, Lyra Chang, Andrea D Thompson, Jason E Gestwicki

Mol Biosyst· September 2012

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