Publications by authors named "Shaun O'Brien"

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Nonredundant Immune Checkpoints Direct Therapeutic Resistance to Chemoimmunotherapy in Pancreatic Ductal Adenocarcinoma.
Meredith L Stone, Veronica M Herrera, Yan Li, Heather Coho, Yuqing Xue, Shaun O'Brien

Cancer Immunol Res· November 2025

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Identification and characterization of tissue resident memory T cells in malignant pleural effusions associated with non-small cell lung cancer.
Caitlin M Tilsed, Joshua Brotman, Shaun O'Brien, Brennan Lee, Edmund Moon

Immunohorizons· April 2025

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Phase I study of BMS-986299, an NLRP3 agonist, as monotherapy and in combination with nivolumab and ipilimumab in patients with advanced solid tumors.
Blessie E Nelson, Shaun O'Brien, Rahul A Sheth, David S Hong, Aung Naing

J Immunother Cancer· January 2025

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Nivolumab monotherapy or combination with ipilimumab with or without cobimetinib in previously treated patients with pancreatic adenocarcinoma (CheckMate 032).
Margaret Callahan, Asim Amin, Frederic J Kaye, Michael A Morse, Matthew H Taylor, Shaun O'Brien

J Immunother Cancer· February 2024

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A Randomized Trial of Autologous Chondrocyte Implantation Versus Alternative Forms of Surgical Cartilage Management in Patients With a Failed Primary Treatment for Chondral or Osteochondral Defects in the Knee.
Martyn Snow, Lee Middleton, Samir Mehta, Andrew Roberts, Richard Gray, Shaun O'Brien

Am J Sports Med· February 2023

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Broken guidewire retrieval from the hip joint: A case report.
Mohanrao Garabadi, Shaun O'Brien

Trauma Case Rep· October 2021

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A human CD137×PD-L1 bispecific antibody promotes anti-tumor immunity via context-dependent T cell costimulation and checkpoint blockade.
Cecile Geuijen, Paul Tacken, Liang-Chuan Wang, Rinse Klooster, Pieter Fokko van Loo, Shaun O'Brien

Nat Commun· July 2021

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Phenotypic and functional analysis of malignant mesothelioma tumor-infiltrating lymphocytes.
Astero Klampatsa, Shaun M O'Brien, Jeffrey C Thompson, Abhishek S Rao, Jason E Stadanlick

Oncoimmunology· February 2021

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Neoadjuvant Gene-Mediated Cytotoxic Immunotherapy for Non-Small-Cell Lung Cancer: Safety and Immunologic Activity.
Jarrod D Predina, Andrew R Haas, Marina Martinez, Shaun O'Brien, Edmund K Moon

Mol Ther· February 2021

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Addition of anti-TIM3 or anti-TIGIT Antibodies to anti-PD1 Blockade Augments Human T cell Adoptive Cell Transfer.
Marina Martinez, Soyeon Kim, Naomi St Jean, Shaun O'Brien, Lurong Lian

Oncoimmunology· January 2021

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Function of Human Tumor-Infiltrating Lymphocytes in Early-Stage Non-Small Cell Lung Cancer.
Shaun M O'Brien, Astero Klampatsa, Jeffrey C Thompson, Marina C Martinez, Wei-Ting Hwang

Cancer Immunol Res· June 2019

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Human tumor-associated monocytes/macrophages and their regulation of T cell responses in early-stage lung cancer.
Sunil Singhal, Jason Stadanlick, Michael J Annunziata, Abhishek S Rao, Pratik S Bhojnagarwala, Shaun O'Brien

Sci Transl Med· February 2019

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Epigenomic-Guided Mass Cytometry Profiling Reveals Disease-Specific Features of Exhausted CD8 T Cells.
Bertram Bengsch, Takuya Ohtani, Omar Khan, Manu Setty, Sasikanth Manne, Shaun O'Brien

Immunity· May 2018

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Provision of total hip replacement for displaced intracapsular hip fracture and the outcomes: audit of local practice based on NICE guidelines.
Lucy C Walker, Ling H Lee, Mark Webb, Julie Walmsley, Shaun O'Brien

Hip Int· January 2017

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CAR T Cell Therapy for Solid Tumors.
Kheng Newick, Shaun O'Brien, Edmund Moon, Steven M Albelda

Annu Rev Med· January 2017

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Origin and Role of a Subset of Tumor-Associated Neutrophils with Antigen-Presenting Cell Features in Early-Stage Human Lung Cancer.
Sunil Singhal, Pratik S Bhojnagarwala, Shaun O'Brien, Edmund K Moon, Alfred L Garfall

Cancer Cell· July 2016

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Augmentation of CAR T-cell Trafficking and Antitumor Efficacy by Blocking Protein Kinase A Localization.
Kheng Newick, Shaun O'Brien, Jing Sun, Veena Kapoor, Steven Maceyko

Cancer Immunol Res· June 2016

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HDAC5 controls the functions of Foxp3(+) T-regulatory and CD8(+) T cells.
Haiyan Xiao, Jing Jiao, Liqing Wang, Shaun O'Brien, Kheng Newick

Int J Cancer· May 2016

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Blockade of Programmed Death 1 Augments the Ability of Human T Cells Engineered to Target NY-ESO-1 to Control Tumor Growth after Adoptive Transfer.
Edmund K Moon, Raghuveer Ranganathan, Evgeniy Eruslanov, Soyeon Kim, Kheng Newick, Shaun O'Brien

Clin Cancer Res· January 2016

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CD38-Expressing Myeloid-Derived Suppressor Cells Promote Tumor Growth in a Murine Model of Esophageal Cancer.
Tatiana A Karakasheva, Todd J Waldron, Evgeniy Eruslanov, Sang-Bae Kim, Ju-Seog Lee, Shaun O'Brien

Cancer Res· October 2015

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Tumor-Promoting Desmoplasia Is Disrupted by Depleting FAP-Expressing Stromal Cells.
Albert Lo, Liang-Chuan S Wang, John Scholler, James Monslow, Diana Avery, Shaun O'Brien

Cancer Res· July 2015

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Increased systolic blood pressure reactivity to acute stress is related with better self-reported health.
Bradley J Wright, Shaun O'Brien, Agnes Hazi, Stephen Kent

Sci Rep· November 2014

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Ikaros imposes a barrier to CD8+ T cell differentiation by restricting autocrine IL-2 production.
Shaun O'Brien, Rajan M Thomas, Gerald B Wertheim, Fuqin Zhang, Hao Shen

J Immunol· June 2014

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Management of significant and widespread, acute subcutaneous emphysema: should we manage surgically or conservatively?
Richard P Jeavons, Daniel Dowen, Paul R P Rushton, Simon Chambers, Shaun O'Brien

J Emerg Med· January 2014

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Antibiotic prophylaxis for hip fracture surgery: three-dose cefuroxime versus single-dose gentamicin and amoxicillin.
Prithee Jettoo, Richard Jeavons, Bobby Siddiqui, Shaun O'Brien

J Orthop Surg (Hong Kong)· December 2013

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