Publications by authors named "Shawn Chen"

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Microbiological evidence for the trisubstituted benzimidazoles targeting MmpL3 in .
Mengyun Zhang, Renee Allen, Lauren Ames, Curtis A Engelhart, Diana Quach, Shawn Chen

Antimicrob Agents Chemother· October 2025

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Identification of a phenyl ester covalent inhibitor of caseinolytic protease and analysis of the ClpP1P2 inhibition in mycobacteria.
Genhui Xiao, Yumeng Cui, Liangliang Zhou, Chuya Niu, Bing Wang, Shawn Chen

mLife· April 2025

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Increasing adherence and collecting symptom-specific biometric signals in remote monitoring of heart failure patients: a randomized controlled trial.
Sukanya Mohapatra, Mirna Issa, Vedrana Ivezic, Rose Doherty, Stephanie Marks, Shawn Chen

J Am Med Inform Assoc· January 2025

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TamGen: drug design with target-aware molecule generation through a chemical language model.
Kehan Wu, Yingce Xia, Pan Deng, Renhe Liu, Yuan Zhang, Si Chen, Shawn Chen, Enhong Chen

Nat Commun· October 2024

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The Projectile Perforation Resistance of Materials: Scaling the Impact Resistance of Thin Films to Macroscale Materials.
Katherine M Evans, Shawn H Chen, Amanda J Souna, Stephan J Stranick, Christopher L Soles

ACS Appl Mater Interfaces· July 2023

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Assessing Boron-Pleuromutilin AN11251 for the Development of Antibacterial Agents.
Ming-Jie Han, Miaomiao Pan, Genhui Xiao, Ying Yuan, Shawn Chen

Molecules· June 2023

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A streamlined process for discovery and characterization of inhibitors against phenylalanyl-tRNA synthetase of Mycobacterium tuberculosis.
Heng Wang, Shawn Chen

Methods Enzymol· January 2023

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Human Kinase IGF1R/IR Inhibitor Linsitinib Controls the In Vitro and Intracellular Growth of .
Heng Wang, Jing Bi, Yuan Zhang, Miaomiao Pan, Qinglong Guo, Shawn Chen

ACS Infect Dis· October 2022

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A Computationally Efficient Approach to Simulate Heart Rate Effects Using a Whole Human Heart Model.
Jiang Yao, Shawn Chen, Julius M Guccione

Bioengineering (Basel)· July 2022

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Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Yuhong Yang, Yuanyuan Xu, Yuan Yue, Heng Wang, Yumeng Cui, Shawn Chen

ACS Chem Biol· January 2022

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Controlling toughness of polymer-grafted nanoparticle composites for impact mitigation.
Shawn H Chen, Amanda J Souna, Stephan J Stranick, Mayank Jhalaria, Sanat K Kumar

Soft Matter· January 2022

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Rediscovery of PF-3845 as a new chemical scaffold inhibiting phenylalanyl-tRNA synthetase in Mycobacterium tuberculosis.
Heng Wang, Min Xu, Curtis A Engelhart, Xi Zhang, Baohua Yan, Shawn Chen

J Biol Chem· August 2021

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Using microprojectiles to study the ballistic limit of polymer thin films.
Shawn H Chen, Amanda J Souna, Christopher L Soles, Stephan J Stranick, Edwin P Chan

Soft Matter· April 2020

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Estimating the Health-Related Quality of Life of Twitter Users Using Semantic Processing.
Karthik V Sarma, Brennan M R Spiegel, Mark W Reid, Shawn Chen, Raina M Merchant

Stud Health Technol Inform· August 2019

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Total synthesis and antimicrobial evaluation of natural albomycins against clinical pathogens.
Zihua Lin, Xiaobo Xu, Sheng Zhao, Xiaohong Yang, Jian Guo, Shawn Chen

Nat Commun· September 2018

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Comparative analysis of FKBP family protein: evaluation, structure, and function in mammals and Drosophila melanogaster.
George Ghartey-Kwansah, Zhongguang Li, Rui Feng, Liyang Wang, Xin Zhou, Frederic Z Chen, Shawn Chen

BMC Dev Biol· March 2018

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Syncytium calcium signaling and macrophage function in the heart.
Xin Zhou, Zhongguang Li, Zefan Wang, Eda Chen, Juan Wang, Frederic Chen, Shawn Chen

Cell Biosci· March 2018

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Nature's combinatorial biosynthesis and recently engineered production of nucleoside antibiotics in Streptomyces.
Shawn Chen, William A Kinney, Steven Van Lanen

World J Microbiol Biotechnol· April 2017

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pH-Controlled Electrochemical Deposition of Polyelectrolyte Complex Films.
Kazi Sadman, Qifeng Wang, Shawn H Chen, David E Delgado, Kenneth R Shull

Langmuir· February 2017

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Direct Formation of Oxocarbenium Ions under Weakly Acidic Conditions: Catalytic Enantioselective Oxa-Pictet-Spengler Reactions.
Chenfei Zhao, Shawn B Chen, Daniel Seidel

J Am Chem Soc· July 2016

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Evaluating topic model interpretability from a primary care physician perspective.
Corey W Arnold, Andrea Oh, Shawn Chen, William Speier

Comput Methods Programs Biomed· February 2016

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A Branch Point of Streptomyces Sulfur Amino Acid Metabolism Controls the Production of Albomycin.
Aditya Kulkarni, Yu Zeng, Wei Zhou, Steven Van Lanen, Weiwen Zhang, Shawn Chen

Appl Environ Microbiol· January 2016

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RadPath: A Web-based System for Integrating and Correlating Radiology and Pathology Findings During Cancer Diagnosis.
Corey W Arnold, W Dean Wallace, Shawn Chen, Andrea Oh, Fereidoun Abtin

Acad Radiol· January 2016

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Analysis of the biosynthesis of antibacterial cyclic dipeptides in Nocardiopsis alba.
Yongli Li, Ying-Mi Lai, Yi Lu, Yu-Liang Yang, Shawn Chen

Arch Microbiol· November 2014

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A replication study for association of ITPKC and CASP3 two-locus analysis in IVIG unresponsiveness and coronary artery lesion in Kawasaki disease.
Ho-Chang Kuo, Yu-Wen Hsu, Chung-Min Wu, Shawn Hsiang-Yin Chen, Kuo-Sheng Hung, Wei-Chiao Chen

PLoS One· February 2014

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