Publications by authors named "Shayne D Wierbowski"

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A multiscale functional map of somatic mutations in cancer integrating protein structure and network topology.
Yingying Zhang, Alden K Leung, Jin Joo Kang, Yu Sun, Guanxi Wu, Shayne D Wierbowski

Nat Commun· January 2025

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A full-proteome, interaction-specific characterization of mutational hotspots across human cancers.
Siwei Chen, Yuan Liu, Yingying Zhang, Shayne D Wierbowski, Steven M Lipkin

Genome Res· January 2022

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A 3D structural SARS-CoV-2-human interactome to explore genetic and drug perturbations.
Shayne D Wierbowski, Siqi Liang, Yuan Liu, You Chen, Shagun Gupta

Nat Methods· December 2021

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Transcription imparts architecture, function and logic to enhancer units.
Nathaniel D Tippens, Jin Liang, Alden King-Yung Leung, Shayne D Wierbowski, Abdullah Ozer

Nat Genet· October 2020

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Structure-based validation can drastically underestimate error rate in proteome-wide cross-linking mass spectrometry studies.
Kumar Yugandhar, Ting-Yi Wang, Shayne D Wierbowski, Elnur Elyar Shayhidin, Haiyuan Yu

Nat Methods· October 2020

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BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Reza Pourhaghighi, Peter E A Ash, Sadhna Phanse, Florian Goebels, Lucas Z M Hu, Shayne D Wierbowski

Cell Syst· August 2020

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A massively parallel barcoded sequencing pipeline enables generation of the first ORFeome and interactome map for rice.
Shayne D Wierbowski, Tommy V Vo, Pascal Falter-Braun, Timothy O Jobe, Lars H Kruse

Proc Natl Acad Sci U S A· May 2020

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BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Reza Pourhaghighi, Peter E A Ash, Sadhna Phanse, Florian Goebels, Lucas Z M Hu, Shayne D Wierbowski

Cell Syst· April 2020

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Cross-docking benchmark for automated pose and ranking prediction of ligand binding.
Shayne D Wierbowski, Bentley M Wingert, Jim Zheng, Carlos J Camacho

Protein Sci· January 2020

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Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
Robert Fragoza, Jishnu Das, Shayne D Wierbowski, Jin Liang, Tina N Tran

Nat Commun· September 2019

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Extracting Complementary Insights from Molecular Phenotypes for Prioritization of Disease-Associated Mutations.
Shayne D Wierbowski, Robert Fragoza, Siqi Liang, Haiyuan Yu

Curr Opin Syst Biol· October 2018

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