Publications by authors named "She-Hung Chan"

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Cardenolide glycosides sensitize gefitinib-induced apoptosis in non-small cell lung cancer: inhibition of Na/K-ATPase serving as a switch-on mechanism.
Chi-Min Du, Wohn-Jenn Leu, Yi-Huei Jiang, She-Hung Chan, Ih-Sheng Chen, Hsun-Shuo Chang

Naunyn Schmiedebergs Arch Pharmacol· September 2024

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A novel HDAC6 inhibitor interferes microtubule dynamics and spindle assembly checkpoint and sensitizes cisplatin-induced apoptosis in castration-resistant prostate cancer.
Pei-Chen Ye, Wohn-Jenn Leu, Tsung-Yu Yeh, Yu-Tung Hsu, Yi-Chin Lin, Yi-Chang Chiang, She-Hung Chan

Prostate· May 2024

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Mechanistic study of dual-function inhibitors targeting topoisomerase II and Rad51-mediated DNA repair pathway against castration-resistant prostate cancer.
Yi-Chang Chiang, Wohn-Jenn Leu, Yi-Chin Chen, Pei-Chen Ye, Yu-Tung Hsu, She-Hung Chan

Prostate· December 2023

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Altered Expression of Interleukin-18 System mRNA at the Level of Endometrial Myometrial Interface in Women with Adenomyosis.
Liang-Hsuan Chen, She-Hung Chan, Chin-Jung Li, Hsien-Ming Wu, Hong-Yuan Huang

Curr Issues Mol Biol· November 2022

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Antileukemic Natural Product Induced Both Apoptotic and Pyroptotic Programmed Cell Death and Differentiation Effect.
Wohn-Jenn Leu, Hsun-Shuo Chang, Ih-Sheng Chen, Jih-Hwa Guh, She-Hung Chan

Int J Mol Sci· October 2021

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Synthesis, distribution analysis and mechanism studies of N-acyl glucosamine-bearing oleanolic saponins.
Yu-Pu Juang, You-Yu Lin, She-Hung Chan, Chun-Kai Chang, Jiun-Jie Shie

Bioorg Chem· June 2020

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Determination of synthetic cathinone α-pyrrolidinovalero-phenone and its metabolite in urine using solid-phase extraction and gas chromatography-mass spectrometry.
Kai-Wen Cheng, Chien-Ming Hsieh, Huei-Wen Chen, Pin-Chieh Chi, Da-Peng Yang, She-Hung Chan

Rapid Commun Mass Spectrom· April 2020

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Mechanistic Study of Triazole Based Aminodiol Derivatives in Leukemic Cells-Crosstalk between Mitochondrial Stress-Involved Apoptosis and Autophagy.
She-Hung Chan, Wohn-Jenn Leu, Sharada Prasanna Swain, Jui-Ling Hsu, Duen-Ren Hou

Int J Mol Sci· April 2020

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Phosphodiesterase Type 5 (PDE5) Inhibitors Sensitize Topoisomerase II Inhibitors in Killing Prostate Cancer Through PDE5-Independent Impairment of HR and NHEJ DNA Repair Systems.
Jo-Fan Chang, Jui-Ling Hsu, Yi-Hua Sheng, Wohn-Jenn Leu, Chia-Chun Yu, She-Hung Chan, Mei-Ling Chan

Front Oncol· January 2019

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An integrated approach to elucidate signaling pathways of dioscin-induced apoptosis, energy metabolism and differentiation in acute myeloid leukemia.
She-Hung Chan, Pi-Hui Liang, Jih-Hwa Guh

Naunyn Schmiedebergs Arch Pharmacol· June 2018

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Design, synthesis and cytotoxic activity of N-Modified oleanolic saponins bearing A glucosamine.
You-Yu Lin, She-Hung Chan, Yu-Pu Juang, Hsin-Min Hsiao, Jih-Hwa Guh

Eur J Med Chem· January 2018

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Enantiomerically pure β-dipeptide derivative induces anticancer activity against human hormone-refractory prostate cancer through both PI3K/Akt-dependent and -independent pathways.
Mei-Ling Chan, Chia-Chun Yu, Jui-Ling Hsu, Wohn-Jenn Leu, She-Hung Chan

Oncotarget· November 2017

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Medical record review for faculty promotion: A cohort analysis.
Chien-Da Huang, Chang-Chyi Jenq, Liang-Shiou Ou, Alvin C Chen, She-Hung Chan

Biomed J· December 2016

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Non-immunosuppressive triazole-based small molecule induces anticancer activity against human hormone-refractory prostate cancers: the role in inhibition of PI3K/AKT/mTOR and c-Myc signaling pathways.
Wohn-Jenn Leu, Sharada Prasanna Swain, She-Hung Chan, Jui-Ling Hsu, Shih-Ping Liu, Mei-Ling Chan, Wei-Ling Chang

Oncotarget· November 2016

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The effects of antiepileptic drugs on the growth of glioblastoma cell lines.
Ching-Yi Lee, Hung-Yi Lai, Angela Chiu, She-Hung Chan, Ling-Ping Hsiao

J Neurooncol· May 2016

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Raised Proinflammatory Cytokine Production Within Cerebrospinal Fluid Precedes Fever Onset in Patients With Neurosurgery-Associated Bacterial Meningitis.
Zhuo-Hao Liu, Po-Hsun Tu, Nan-Yu Chen, Ping K Yip, Amy L Bowes, She-Hung Chan

Crit Care Med· November 2015

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Asymmetric synthesis of (-)-brevipolide H through cyclopropanation of the α,β-unsaturated ketone.
Jing-Wen Lin, Yudhi Dwi Kurniawan, Wen-Jung Chang, Wohn-Jenn Leu, She-Hung Chan

Org Lett· October 2014

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Reevesioside A, a cardenolide glycoside, induces anticancer activity against human hormone-refractory prostate cancers through suppression of c-myc expression and induction of G1 arrest of the cell cycle.
Wohn-Jenn Leu, Hsun-Shuo Chang, She-Hung Chan, Jui-Ling Hsu, Chia-Chun Yu

PLoS One· September 2014

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Synthesis and anti-cancer activity of a glycosyl library of N-acetylglucosamine-bearing oleanolic acid.
Yi-Bing Zeng, Hsin-Min Hsiao, She-Hung Chan, Ying-Hsin Wang, You-Yu Lin

Mol Divers· February 2014

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Terfenadine induces anti-proliferative and apoptotic activities in human hormone-refractory prostate cancer through histamine receptor-independent Mcl-1 cleavage and Bak up-regulation.
Wei-Ting Wang, Yen-Hui Chen, Jui-Ling Hsu, Wohn-Jenn Leu, Chia-Chun Yu, She-Hung Chan

Naunyn Schmiedebergs Arch Pharmacol· January 2014

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Reevesioside F induces potent and efficient anti-proliferative and apoptotic activities through Na⁺/K⁺-ATPase α3 subunit-involved mitochondrial stress and amplification of caspase cascades.
She-Hung Chan, Wohn-Jenn Leu, Lih-Ching Hsu, Hsun-Shuo Chang, Tsong-Long Hwang

Biochem Pharmacol· December 2013

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A method to develop an in vitro osteoporosis model of porcine vertebrae: histological and biomechanical study.
Ching-yi Lee, She-Hung Chan, Hung-Yi Lai, Shih-Tseng Lee

J Neurosurg Spine· June 2011

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Eutopic endometrial interleukin-18 system mRNA and protein expression at the level of endometrial-myometrial interface in adenomyosis patients.
Hong-Yuan Huang, Hsing-Tse Yu, She-Hung Chan, Chyi-Long Lee, Hsin-Shih Wang

Fertil Steril· June 2010

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Granulosa-lutein cell growth differentiation factor-9 (GDF-9) messenger RNA and protein expression in in vitro fertilization (IVF) cycles: relation to characteristics of ovulation induction and IVF.
Hong-Yuan Huang, Hsin-Shih Wang, She-Hung Chan, Chyi-Long Lee, Chia-Woei Wang

Fertil Steril· April 2009

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Interleukin-18 system messenger RNA and protein expression in human endometrium during the menstrual cycle.
Hong-Yuan Huang, She-Hung Chan, Hsing-Tse Yu, Hsin-Shih Wang, Chyong-Huey Lai

Fertil Steril· October 2006

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