Publications by authors named "Shengcai Lin"

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Glucose starvation mimetic aldometanib removes immune barriers permitting mice with hepatocellular carcinoma to live to normal ages.
Hui-Hui Hu, Xuefeng Wang, Bin Lan, Haili Cheng, Hong Wen, Shiyu Lin, Jieyu Lin, Sheng-Cai Lin

Cell Res· December 2025

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Oligodendrocyte precursor cell-specific blocking of low-glucose-induced activation of AMPK ensures myelination and remyelination.
Yuxia Sun, Wei-Wei Zhang, Lu Men, Jianfeng Wu, Luming Yao, David Carling, Sheng-Cai Lin

Nat Metab· November 2025

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Lithocholic acid phenocopies anti-ageing effects of calorie restriction.
Qi Qu, Yan Chen, Yu Wang, Shating Long, Weiche Wang, Sheng-Cai Lin

Nature· July 2025

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Lithocholic acid binds TULP3 to activate sirtuins and AMPK to slow down ageing.
Qi Qu, Yan Chen, Yu Wang, Weiche Wang, Shating Long, Liyun Lin, Sheng-Cai Lin

Nature· July 2025

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Methods to Determine Lysosomal AMPK Activation.
Chen-Song Zhang, Sheng-Cai Lin

Methods Mol Biol· May 2025

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Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK.
Mengqi Li, Chen-Song Zhang, Yue Zong, Jin-Wei Feng, Teng Ma, Zhizhong Lin, Shu-Yong Lin, Sheng-Cai Lin

Cell Metab· February 2025

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Author Correction: Lithocholic acid phenocopies anti-ageing effects of calorie restriction.
Qi Qu, Yan Chen, Yu Wang, Shating Long, Weiche Wang, Sheng-Cai Lin

Nature· February 2025

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Metabolic stress induces a double-positive feedback loop between AMPK and SQSTM1/p62 conferring dual activation of AMPK and NFE2L2/NRF2 to synergize antioxidant defense.
Eun-Ji Choi, Hyun-Taek Oh, Seon-Hyeong Lee, Chen-Song Zhang, Mengqi Li, Sheng-Cai Lin

Autophagy· November 2024

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AMPK-PDZD8-GLS1 axis mediates calorie restriction-induced lifespan extension.
Mengqi Li, Yu Wang, Xiaoyan Wei, Wei-Feng Cai, Yan-Hui Liu, Liyun Lin, Sheng-Cai Lin

Cell Res· November 2024

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AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine.
Mengqi Li, Yu Wang, Xiaoyan Wei, Wei-Feng Cai, Jianfeng Wu, Shu-Yong Lin, Sheng-Cai Lin

Cell Res· October 2024

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Formation of Multiple Intracranial Aneurysms Caused by Takayasu Arteritis.
Fuling Huang, Shengcai Lin

Radiology· October 2024

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Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate.
Yu-Qing Wu, Chen-Song Zhang, Jinye Xiong, Dong-Qi Cai, Chen-Zhe Wang, Huiling Guo, Shu-Yong Lin, Sheng-Cai Lin

Cell Res· November 2023

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Visualization of the Lenticulostriate artery with 3-dimensional time-of-flight magnetic resonance angiography combined with the compressed sensing technique using a 3-T magnetic resonance imaging system.
Fuling Huang, Yurong Guo, Ruchang Chen, Shengcai Lin

Magn Reson Imaging· October 2023

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Cinematic Rendering of Lower Extremity Varicose Veins.
Fuling Huang, Shengcai Lin

Radiology· July 2023

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Hierarchical inhibition of mTORC1 by glucose starvation-triggered AXIN lysosomal translocation and by AMPK.
Mengqi Li, Xiaoyan Wei, Jinye Xiong, Jin-Wei Feng, Chen-Song Zhang, Sheng-Cai Lin

Life Metab· June 2023

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AMPK directly phosphorylates TBK1 to integrate glucose sensing into innate immunity.
Qian Zhang, Shengduo Liu, Chen-Song Zhang, Qirou Wu, Xinyuan Yu, Sheng-Cai Lin

Mol Cell· December 2022

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Identification of serum metabolites enhancing inflammatory responses in COVID-19.
Chen-Song Zhang, Bingchang Zhang, Mengqi Li, Xiaoyan Wei, Kai Gong, Sheng-Cai Lin

Sci China Life Sci· October 2022

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The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK.
Chen-Song Zhang, Mengqi Li, Yu Wang, Xiaoyang Li, Yue Zong, Shu-Yong Lin, Sheng-Cai Lin

Nat Metab· October 2022

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Midkine noncanonically suppresses AMPK activation through disrupting the LKB1-STRAD-Mo25 complex.
Tian Xia, Di Chen, Xiaolong Liu, Huan Qi, Wen Wang, Ting Ling, Sheng-Cai Lin

Cell Death Dis· April 2022

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Low-dose metformin targets the lysosomal AMPK pathway through PEN2.
Teng Ma, Xiao Tian, Baoding Zhang, Mengqi Li, Yu Wang, Shu-Yong Lin, Sheng-Cai Lin

Nature· March 2022

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Nuclear UHRF1 is a gate-keeper of cellular AMPK activity and function.
Xiang Xu, Guangjin Ding, Caizhi Liu, Yuhan Ding, Xiaoxin Chen, Shu-Hai Lin, Sheng-Cai Lin

Cell Res· January 2022

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Aldolase is a sensor for both low and high glucose, linking to AMPK and mTORC1.
Mengqi Li, Chen-Song Zhang, Jin-Wei Feng, Xiaoyan Wei, Cixiong Zhang, Sheng-Cai Lin

Cell Res· April 2021

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AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1.
Meng Shi, Xiao-Yu Huang, Xin-Yi Ren, Xiao-Yan Wei, Yue Ma, Zhi-Zhong Lin, Lintao Song, Shu-Yong Lin, Sheng-Cai Lin

Nat Cell Biol· March 2021

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SRC promotes lipogenesis: implications for obesity and breast cancer.
Shu-Yong Lin, Sheng-Cai Lin

Mol Cell Oncol· January 2021

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Proto-oncogene Src links lipogenesis via lipin-1 to breast cancer malignancy.
Lintao Song, Zhihua Liu, Hui-Hui Hu, Ying Yang, Terytty Yang Li, Zhi-Zhong Lin, Shu-Yong Lin, Sheng-Cai Lin

Nat Commun· November 2020

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